Patents by Inventor Shishan Yu

Shishan Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12098176
    Abstract: Provided are keratin BD-4, an encoding nucleic acid molecule thereof, an expression vector, a host cell, and a pharmaceutical composition containing the keratin. The keratin BD-4 can be used for preparing drugs having antipyretic and analgesic, antitussive and expectorant, and antiepileptic effects.
    Type: Grant
    Filed: October 28, 2020
    Date of Patent: September 24, 2024
    Assignee: Institute of Materia Medica, Chinese Academy of Medical Sciences
    Inventors: Shishan Yu, Xiaoliang Wang, Jing Qu, Mi Li, Guozhu Su, Ling Wang, Jie Cai, Shaofeng Xu, Jiang Fu
  • Publication number: 20240124556
    Abstract: The present invention provides a keratin BD-3, a nucleic acid molecule encoding same, an expression vector, a host cell, a preparation method therefor, and a pharmaceutical composition contained the keratin BD-3. The keratin BD-3 can be used in the preparation of medicament for antipyretic, analgesic, antitussive, expectorant, anticonvulsant, antiepileptic, anti-hypertension, anti-inflammatory, and antiviral.
    Type: Application
    Filed: October 28, 2020
    Publication date: April 18, 2024
    Inventors: Shishan YU, Xiaoliang WANG, Jing QU, Jiang FU, Ling WANG, Jie CAI, Mi LI, Nan FENG, Guoru SHI
  • Publication number: 20230287068
    Abstract: The present invention provides a keratin BD-6, a nucleic acid molecule encoding keratin BD-6, an expression vector containing the nucleic acid molecule, and a host cell containing the expression vector or the nucleic acid molecule integrated into genome, and preparation method of the keratin BD-6, and a pharmaceutical composition containing the keratin BD-6, and use of the above keratin BD-6, nucleic acid molecule, expression vector, host cell or pharmaceutical composition in the preparation of medicament for antipyretic, analgesic, antitussive, expectorant, anticonvulsant, antiepileptic, anti-hypertension, anti-inflammatory, and antiviral.
    Type: Application
    Filed: October 28, 2020
    Publication date: September 14, 2023
    Inventors: Shishan YU, Xiaoliang WANG, Guoru SHI, Yunbao LIU, Yong LI, Ling WANG, Jiang LI, Nan FENG, Mi LI
  • Publication number: 20230183305
    Abstract: The present invention provides a keratin BD-11, an encoding nucleic acid molecule, an expression vector, a host cell, a preparation method thereof, and a pharmaceutical composition containing the keratin. The keratin BD-11 can be used in the preparation of medicamnet for antipyretic, analgesic, antitussive, expectorant, anticonvulsant, antiepileptic, anti-hypertension, anti-inflammatory, and antiviral.
    Type: Application
    Filed: October 28, 2020
    Publication date: June 15, 2023
    Inventors: Shishan YU, Xiaoliang WANG, Jiang FU, Yong LI, Mi ZHANG, Nan FENG, Guozhu SU, Jiang LI, Yunbao LIU
  • Publication number: 20230146533
    Abstract: The present invention provides a keratin BD-10, an encoding nucleic acid molecule, an expression vector, a host cell thereof, a preparation method for BD-10, and a pharmaceutical composition containing the keratin BD-10. Also provides the use of the keratin BD-10, nucleic acid molecule, expression vector, host cell or pharmaceutical composition in the preparation of medicament for antipyretic, analgesic, antitussive, expectorant, anticonvulsant, antiepileptic, anti-hypertension, anti-inflammatory, and antiviral.
    Type: Application
    Filed: October 28, 2020
    Publication date: May 11, 2023
    Inventors: Shishan YU, Xiaoliang WANG, Jiang FU, Yunbao LIU, Nan FENG, Mi ZHANG, Guoru SHI, Jie CAI
  • Publication number: 20220372091
    Abstract: Provided are keratin BD-4, an encoding nucleic acid molecule thereof, an expression vector, a host cell, and a pharmaceutical composition containing the keratin. The keratin BD-4 can be used for preparing drugs having antipyretic and analgesic, antitussive and expectorant, and antiepileptic effects.
    Type: Application
    Filed: October 28, 2020
    Publication date: November 24, 2022
    Inventors: Shishan YU, Xiaoliang WANG, Jing QU, Mi LI, Guozhu SU, Ling WANG, Jie CAI, Shaofeng XU, Jiang FU
  • Patent number: 9393277
    Abstract: The present invention discloses an Albizzia chinensis extract used in the preparation of a drug for the treatment of gastric ulcers. Specifically, it discloses an Albizzia chinensis (Osbeck) Merr extract and its preparation method including the stems bark of Albizzia chinensis was successively grounded, extracted, concentrated and purificated, as well as a pharmaceutical composition comprising the Albizzia chinensis extract. Through pharmacological test, it has been demonstrated that, the Albizzia chinensis extract showed strong inhibition activity against proton pumps, and it can be used for the treatment of gastric ulcers, chronic gastritis and other acid-related diseases, and its anti-ulcer effect is significant, quick, safe and reliable.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: July 19, 2016
    Assignee: Institute of Materia Medica, Chinese Academy of Medical Sciences
    Inventors: Shishan Yu, Jianjun Zhang, Shuanggang Ma, Ruiming Xu, Chengxue Ji
  • Publication number: 20150010664
    Abstract: The present invention discloses an Albizzia chinensis extract used in the preparation of a drug for the treatment of gastric ulcers. Specifically, it discloses an Albizzia chinensis (Osbeck) Merr extract and its preparation method including the stems bark of Albizzia chinensis was successively grounded, extracted, concentrated and purificated, as well as a pharmaceutical composition comprising the Albizzia chinensis extract. Through pharmacological test, it has been demonstrated that, the Albizzia chinensis extract showed strong inhibition activity against proton pumps, and it can be used for the treatment of gastric ulcers, chronic gastritis and other acid-related diseases, and its anti-ulcer effect is significant, quick, safe and reliable.
    Type: Application
    Filed: October 24, 2012
    Publication date: January 8, 2015
    Inventors: Shishan Yu, Jianjun Zhang, Shuanggang Ma, Ruiming Xu, Chengxue Ji
  • Publication number: 20120190703
    Abstract: The present invention relates to the salts of (+)-13a-(S)-deoxytylophorinine represented by the general formula (I), the preparation method thereof, the pharmaceutical compositions containing them, and their use as medicaments for prevention and/or treatment of cancer and/or inflammation disease.
    Type: Application
    Filed: July 9, 2010
    Publication date: July 26, 2012
    Applicant: INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Shishan Yu, Xiaoguang Chen, Haining Lv, Yan Li, Song Xu, Shuanggang Ma, Zhenjia Liu, Yi Zhang, Jinping Hu