Patents by Inventor Shivali Ashwin Gulab

Shivali Ashwin Gulab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of DNMT1 as anticancer therapeutic agents
    Patent number: 11518779
    Abstract: Provided herein are inhibitors of DNA methyltransferase 1 (an enzyme responsible for the maintenance of DNA CpG methylation marks in human cells) and their use for inhibiting DNA methyltransferase 1. The invention relates to compounds, pharmaceutical compositions, and methods for inhibiting DNA methyltransferase 1.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: December 6, 2022
    Assignees: Victoria Link Limited, Albert Einstein College of Medicine
    Inventors: Peter Charles Tyler, Farah Lamiable-Oulaidi, Anthony David Woolhouse, Shivali Ashwin Gulab, Karl Jürgen Shaffer, Ashna Ashneen Khan, Douglas Ronald Crump, Vern L. Schramm, Quan Du
  • GLYCOPEPTIDE VACCINE
    Publication number: 20220233668
    Abstract: The present invention generally relates to a glycopeptide conjugate compound of Formula (I):, as described herein, compositions comprising the conjugate compound and to the use of such a compound to as a vaccine.
    Type: Application
    Filed: May 8, 2020
    Publication date: July 28, 2022
    Inventors: Dale Ian GODFREY, William Ross HEATH, Lauren Eelise HOLZ, Ian Francis HERMANS, Gavin Frank PAINTER, Regan James ANDERSON, Benjamin Jason COPTON, Shivali Ashwin GULAB
  • Treatment of helicobacter pylori infections
    Patent number: 11186575
    Abstract: Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering to the subject an inhibitor of H.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: November 30, 2021
    Assignees: Alber Einslein College of Medicine, Victoria Link Limited
    Inventors: Vern L. Schramm, Shanzhi Wang, Antti Marko Haapalainen, Gary Brian Evans, Richard Hubert Furneaux, Keith Clinch, Peter Charles Tyler, Shivali Ashwin Gulab
  • INHIBITORS OF DNMT1 AS ANTICANCER THERAPEUTIC AGENTS
    Publication number: 20210206795
    Abstract: Inhibitors of DNA methyltransferase 1 (an enzyme responsible for the maintenance of DNA CpG methylation marks in human cells) and their use as therapeutic agents against various cancers. The invention relates to compounds, pharmaceutical compositions, methods for inhibiting DNA methyltransferase 1, and methods for treating cancer. The inhibitors are compounds of the general formula.
    Type: Application
    Filed: July 9, 2019
    Publication date: July 8, 2021
    Inventors: Peter Charles Tyler, Farah Lamiable-Oulaidi, Anthony David Woolhouse, Shivali Ashwin Gulab, Karl Jürgen Shaffer, Ashna Ashneen Khan, Douglas Ronald Crump, Vern L. Schramm, Quan Du
  • Treatment of infections using MTAN inhibitors
    Patent number: 10294233
    Abstract: Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H. pylori MTAN (5?-methylthioadenosine nucleosidase) to the subject.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: May 21, 2019
    Assignees: Albert Einstein College of Medicine, Victoria Link Limited
    Inventors: Vern L. Schramm, Keith Clinch, Shivali Ashwin Gulab
  • TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS
    Publication number: 20190016730
    Abstract: Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H. pylori MTAN (5?-methylthioadenosine nucleosidase) to the subject.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 17, 2019
    Applicants: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC., VICTORIA LINK LIMITED
    Inventors: Vern L. Schramm, Keith Clinch, Shivali Ashwin Gulab
  • Treatment of H. pylori infections using MTAN inhibitors
    Patent number: 10118928
    Abstract: Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: November 6, 2018
    Assignees: Albert Einstein College of Medicine, Inc., Victoria Link Limited
    Inventors: Vern L. Schramm, Keith Clinch, Shivali Ashwin Gulab
  • TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS
    Publication number: 20170166571
    Abstract: Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H. pylori MTAN (5?-methylthioadenosine nucleosidase) to the subject.
    Type: Application
    Filed: February 6, 2015
    Publication date: June 15, 2017
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
    Inventors: Vern L. Schramm, Keith Clinch, Shivali Ashwin Gulab
  • TREATMENT OF HELICOBACTER PYLORI INFECTIONS
    Publication number: 20150210701
    Abstract: Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H. pylori MTAN (5?-methylthioadenosine nucleosidase) to the subject.
    Type: Application
    Filed: August 7, 2013
    Publication date: July 30, 2015
    Applicants: ALBERTEINSTIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, CALLAGHAN INNOVATION RESEARCH LIMITED
    Inventors: Vern L. Schramm, Shanzhi Wang, Antti Marko Haapalainen, Gary Brian Evans, Richard Hubert Furneaux, Keith Clinch, Peter Charles Tyler, Shivali Ashwin Gulab
  • Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases
    Patent number: 8853224
    Abstract: The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: October 7, 2014
    Assignees: Industrial Research Limited, Albert Einstein College of Medicine of Yeshiva University
    Inventors: Keith Clinch, Gary Brian Evans, Richard Hubert Furneaux, Shivali Ashwin Gulab, Peter Michael Kelly, Vern L. Schramm, Peter Charles Tyler, Anthony David Woolhouse
  • Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases
    Publication number: 20110130412
    Abstract: The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
    Type: Application
    Filed: September 7, 2007
    Publication date: June 2, 2011
    Inventors: Keith Clinch, Gary Brian Evans, Richard Hubert Furneaux, Shivali Ashwin Gulab, Peter Michael Kelly, Vern L. Schramm, Peter Charles Tyler, Anthony David Woolhouse