Patents by Inventor Shivaputra A. Patil

Shivaputra A. Patil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromenopyridine-based compounds and methods of making and use thereof
    Patent number: 11814392
    Abstract: Chromenopyridine-based compounds are provided. In one aspect, the present disclosure provides a method for treating cancer in a subject in need thereof, the method comprising administering a therapeutically effective amount of a chromenopyridine-based compound to the subject. A representative compound is 2,4-diamino-7,8-dimethoxy-5-((4-methoxyphenyl)thio)-5H-chromeno[2,3-b]pyridine-3-carbonitrile (Compound 1).
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: November 14, 2023
    Assignee: Rosalind Franklin University of Medicine and Science
    Inventors: June A Mayor, Shivaputra A. Patil, Ronald S. Kaplan
  • CHROMENOPYRIDINE-BASED COMPOUNDS AND METHODS OF MAKING AND USE THEREOF
    Publication number: 20220135581
    Abstract: Chromenopyridine-based compounds are provided. In one aspect, the present disclosure provides a method for treating cancer in a subject in need thereof, the method comprising administering a therapeutically effective amount of a chromenopyridine-based compound to the subject. A representative compound is 2,4-diamino-7,8-dimethoxy-5-((4-methoxyphenyl)thio)-5H-chromeno[2,3-b]pyridine-3-carbonitrile (Compound 1).
    Type: Application
    Filed: October 29, 2021
    Publication date: May 5, 2022
    Inventors: June A. Mayor, Shivaputra A. Patil, Ronald S. Kaplan
  • Inhibitors of paxillin function and related compositions and methods
    Patent number: 9834525
    Abstract: This disclosure relates to small molecule inhibitors of paxillin and paxillin binding, and related compositions and methods of treatment.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: December 5, 2017
    Assignee: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Charles Ryan Yates, Duane D. Miller, Frank Park, Jordan J. Toutounchian, Vanessa Morales-Tirado, Shivaputra Patil, Jayaprakash Pagadala, Bilal Abou Aleiwi
  • INHIBITORS OF PAXILLIN FUNCTION AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20160347725
    Abstract: This disclosure relates to small molecule inhibitors of paxillin and paxillin binding, and related compositions and methods of treatment.
    Type: Application
    Filed: February 4, 2015
    Publication date: December 1, 2016
    Inventors: Charles Ryan Yates, Duane D. Miller, Frank Park, Jordan J. Toutounchian, Vanessa Moraies-Tirado, Shivaputra Patil, Jayaprakash Pagadala, Bial Abou Aleiwi
  • 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES EFFECTIVE AS ANTIGLIOMA AGENTS, METHODS OF MAKING, AND THEIR USE
    Publication number: 20120059032
    Abstract: Disclosed are tetrahydroisoquinoline-derivative compounds effective for killing cancer cells, shrinking tumor size, and treating cancer.
    Type: Application
    Filed: March 7, 2011
    Publication date: March 8, 2012
    Applicant: University of Tennessee Research Foundation
    Inventors: Renukadevi Patil, Shivaputra A. Patil, Duane D. Miller, Charles Ryan Yates, Eldon E. Geisert
  • 1-aryl-or 1-heteroaryl-pyrido[B]indoles and uses thereof
    Publication number: 20100317667
    Abstract: Provided herein are 1-aryl or 1-heteroarylsubstituted phenanthrene diketo acid compounds. These compounds comprise a ?-carboline ring structure substituted at C1 with an aryl or heteroaryl moiety and individually substituted at C3-C8 and N9 with a C1-C4 alkyl, a C1-C4 alkoxy, a C1-C4 alkoxyphenyl, halogen, thiol, alkylthiol, sulfonyl, sulfomainde, amide, substituted amide, ester, nitrile, OH, amino, substituted amine, haloalkyl, haloalkoxy, acyl, or a hydrogen. Also provided are methods for inhibiting proliferation of a cancer cell or for treating a cell proliferative disease by contacting the cancer cell or tumor comprising the same with the compounds provided herein or by administering the compounds to a subject with a cell proliferative disease.
    Type: Application
    Filed: April 26, 2010
    Publication date: December 16, 2010
    Inventors: John K. Buolamwini, Shivaputra Patil, James K. Addo, D. Parker Suttle, Ruiwen Zhang, Zhengxiang Zhu, Sharma Horrick