Abstract: Described are contact lenses that contain high energy visible (HEV) light absorbing compounds and their use for improving one or more vision attributes.

Abstract: Provided is a method for forming an ophthalmic lens as well as a lens formed by such method. The method includes the curing of a reactive monomer mixture within a mold assembly under conditions to permit incorporation of functional features into selective portions of the ophthalmic lens.

Abstract: Described are polymerizable high energy light absorbing compounds. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

Abstract: This invention is directed to compounds and compositions which are designed for use in light adjustable ophthalmic devices, such as intraocular implants, intraocular lenses, phakic intraocular lenses, contact lenses, orthokeratology lenses, rigid gas permeable lenses, corneal inlays, corneal outlays, or corneal inserts. The inventive compositions are produced from reactive monomer mixtures which when polymerized form polymers or polymeric networks having editable refractive indices. Such inventive compositions when exposed to light of certain wavelengths undergo intramolecular cycloaddition reactions thereby changing the refractive index in the irradiated regions. When used in ophthalmic devices, the inventive compositions enable post-manufacturing and/or post-operative adjustments to the optics of the devices by spatially modifying the refractive index.

Abstract: This invention is directed to compounds and compositions which are designed for use in light adjustable ophthalmic devices, such as intraocular implants, intraocular lenses, phakic intraocular lenses, contact lenses, orthokeratology lenses, rigid gas permeable lenses, corneal inlays, corneal outlays, or corneal inserts. The inventive compositions are produced from reactive monomer mixtures which when polymerized form polymers or polymeric networks having editable refractive indices. Such inventive compositions when exposed to light of certain wavelengths undergo intramolecular cycloaddition reactions thereby changing the refractive index in the irradiated regions. When used in ophthalmic devices, the inventive compositions enable post-manufacturing and/or post-operative adjustments to the optics of the devices by spatially modifying the refractive index.

Abstract: Described are polymerizable high energy light absorbing compounds. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

Abstract: Described are polymerizable high energy light absorbing compounds. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices. Such devices exhibit a number of desirable properties, including favorable vision break-up times.

Abstract: Described are visible light absorbing compounds. The compounds have a visible light absorption maximum between 430 and 480 nm and a full width half maximum (FWHM) at the visible light absorption maximum of at least 35 nm and up to 100 nanometers, wherein the compounds are photostable. The compounds substantially mimic the visible light absorbance properties of macular pigment while remaining photostable. The compounds may be used in a variety of articles, including ophthalmic devices.

Abstract: Described are polymerizable fused tricyclic compounds of formula I: wherein R1, R2, R3, m, n, t, and rings B, C, and D are as defined herein. The compounds absorb various wavelengths of ultraviolet and/or visible light (such as high energy visible light) and are suitable for incorporation in a variety of products, such as biomedical devices and ophthalmic devices.

Abstract: Described are multifocal contact lenses that contain high energy visible (HEV) light absorbing compounds and their use for improving one or more vision attributes.

Abstract: Described are polymerizable high energy light absorbing compounds. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices. Such devices exhibit a number of desirable properties, including providing wearers with favorable optical quality.

Abstract: Described are contact lenses containing light absorbing chromophores, wherein the light absorbing chromophore is concentrated in one or more select regions of the lens. Also described are methods for making such contact lenses.

Abstract: Described are toric contact lenses that contain high energy visible (HEV) light absorbing compounds and their use for improving various vision attributes in astigmatic contact lens wearers, such as brightness perception and visual range.

Abstract: Described are polymerizable fused tricyclic compounds of formula I: wherein R1, R2, R3, m, n, t, and rings B, C, and D are as defined herein. The compounds absorb various wavelengths of ultraviolet and/or visible light (such as high energy visible light) and are suitable for incorporation in a variety of products, such as biomedical devices and ophthalmic devices.

Abstract: Described are visible light absorbing compounds. The compounds have a visible light absorption maximum between 430 and 480 nm and a full width half maximum (FWHM) at the visible light absorption maximum of at least 35 nm and up to 100 nanometers, wherein the compounds are photostable. The compounds substantially mimic the visible light absorbance properties of macular pigment while remaining photostable. The compounds may be used in a variety of articles, including ophthalmic devices.

Abstract: Described are contact lenses that contain high energy visible (HEV) light absorbing compounds and their use for improving one or more vision attributes.

Abstract: Described are polymerizable high energy light absorbing compounds. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices. Such devices exhibit a number of desirable properties, including favorable rates of pervaporation.

Abstract: Described is an ophthalmic device that contains visible light filters. The ophthalmic device is a free radical reaction product of a reactive mixture comprising: one or more monomers suitable for making the ophthalmic device; a first visible light filtering compound, the first visible light filtering compound having a visible light absorption maximum between 430 and 480 nm and a full width half maximum (FWHM) at the visible light absorption maximum of at least 35 nm and up to 150 nanometers, wherein the compound is photostable, and wherein the compound has a molar extinction coefficient of at least 7740 L·mol?1·cm?1; and a second visible light filtering compound. The devices may provide one or more benefits to wearers, including enhanced macular pigment optical density (MPOD), as well as improved color perception and color enhancement.

Abstract: Described are multifocal contact lenses that contain high energy visible (HEV) light absorbing compounds and their use for improving one or more vision attributes.

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator, (c) combining the crosslinked substrate network with a second reactive composition containing one or more ethylenically unsaturated compounds; and (d) activating the covalently bound activatable free radical initiator of the crosslinked substrate network such that the second reactive composition polymerizes therein with the crosslinked substrate network to form a grafted polymeric network and a