Patents by Inventor Shivnath Patil

Shivnath Patil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of hydroxocobalamin hydrochloride
    Patent number: 11324771
    Abstract: A process for the preparation of hydroxocobalamin hydrochloride. More particularly the present application relates to improved process for the preparation of Hydroxocobalamin hydrochloride. In addition the present application also relates to process for the preparation of novel amorphous form. This application particularly relates to a process for the industrial manufacture of hydroxocobalamin hydrochloride from cyanocobalamin. The present application also relates to the improvement in yield with better purity of Hydroxocobalamin hydrochloride.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: May 10, 2022
    Assignee: RK Pharma Solutions LLC
    Inventors: Ravishanker Kovi, Jayaraman Kannappan, Shivnath Patil, Chowdari Bhushaiah Talluri, Aditya Khanvilkar, Govind Ahirrao
  • PROCESS FOR THE PREPARATION OF FERRIC CITRATE
    Publication number: 20210332073
    Abstract: Method are provided for obtaining ferric citrate that includes the step(s) of reacting ferric chloride with a suitable base to obtain ferric hydroxide; reacting the ferric hydroxide with citric acid to obtain ferric citrate; and processing the ferric citrate to obtain ferric citrate. The resulting ferric citrate has a specific surface area greater than 16 sq. m/g, but less than 20 sq. m/g.
    Type: Application
    Filed: September 28, 2020
    Publication date: October 28, 2021
    Inventors: Ravishanker Kovi, Jayaraman Kannappan, Shivnath Patil, Srikrishna Apar, Govind Ahirrao, Shrikant Wadajkar
  • PROCESS FOR THE PREPARATION OF HYDROXOCOBALAMIN HYDROCHLORIDE
    Publication number: 20210252037
    Abstract: A process for the preparation of hydroxocobalamin hydrochloride. More particularly the present application relates to improved process for the preparation of Hydroxocobalamin hydrochloride. In addition the present application also relates to process for the preparation of novel amorphous form. This application particularly relates to a process for the industrial manufacture of hydroxocobalamin hydrochloride from cyanocobalamin. The present application also relates to the improvement in yield with better purity of Hydroxocobalamin hydrochloride.
    Type: Application
    Filed: June 24, 2020
    Publication date: August 19, 2021
    Inventors: Ravishanker Kovi, Jayaraman Kannappan, Shivnath Patil, Chowdari Bhushaiah Talluri, Aditya Khanvilkar, Govind Ahirrao
  • PROCESS FOR THE PREPARATION OF ERIBULIN MESYLATE INTERMEDIATE
    Publication number: 20210040107
    Abstract: The present application provides improved processes for the synthesis of eribulin intermediate, which generally comprise the steps of: a) De-protecting the eribulin-enone (compound 1) in tetrahydrofuran by using TBAF solution, buffered with imidazole HCl in the presence of molecular sieve and sodium sulphate to get an insitu mixture of eribulin-dione diastereomer at C12 carbon (compound 2). Then ketalization may be performed of eribulin-dione insitu intermediate containing mixture of diastereomer at C12 carbon (compound 2) with PPTS in dichloromethane to yield eribulin-diol (compound 3).
    Type: Application
    Filed: June 11, 2020
    Publication date: February 11, 2021
    Inventors: Ravishanker Kovi, Jayaraman Kannnappan, Shivnath Shivnath Patil