Patents by Inventor Shiwei Song

Shiwei Song has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130017580
    Abstract: The present disclosure relates to non-naturally occurring monooxygenase polypeptides useful for preparing prazole compounds, polynucleotides encoding the polypeptides, and methods of using the polypeptides.
    Type: Application
    Filed: December 8, 2010
    Publication date: January 17, 2013
    Applicant: CODEXIS, INC.
    Inventors: Yong Koy Bong, Michael D. Clay, Steven J. Collier, Benjamin Mijts, Michael Vogel, Xiyun Zhang, Jun Zhu, Jovana Nazor, Derek Smith, Shiwei Song
  • Publication number: 20120220002
    Abstract: The present disclosure provides engineered halohydrin dehalogenase (HHDH) polypeptides having improved enzyme properties as compared to the wild-type HHDH enzyme HheC and other reference engineered HHDH polypeptides. Also provided are polynucleotides encoding the engineered HHDH enzymes, host cells capable of expressing the engineered HHDH enzymes, and methods of using the engineered HHDH enzymes to synthesize a variety of chiral compounds including chiral epoxides and chiral alcohols.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 30, 2012
    Applicant: CODEXIS, INC.
    Inventors: Erik De Vries, Louis Clark, Scott McVicar, Erika Segraves, Shiwei Song, Kheng Lin Tan
  • Patent number: 8187856
    Abstract: The present disclosure provides engineered halohydrin dehalogenase (HHDH) polypeptides having improved enzyme properties as compared to the wild-type HHDH enzyme HheC and other reference engineered HHDH polypeptides. Also provided are polynucleotides encoding the engineered HHDH enzymes, host cells capable of expressing the engineered HHDH enzymes, and methods of using the engineered HHDH enzymes to synthesize a variety of chiral compounds including chiral epoxides and chiral alcohols.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: May 29, 2012
    Assignee: Codexis, Inc.
    Inventors: Erik De Vries, Louis Clark, Scott McVicar, Erika Segraves, Shiwei Song, Kheng Lin Tan
  • Publication number: 20100173372
    Abstract: The present disclosure provides engineered halohydrin dehalogenase (HHDH) polypeptides having improved enzyme properties as compared to the wild-type HHDH enzyme HheC and other reference engineered HHDH polypeptides. Also provided are polynucleotides encoding the engineered HHDH enzymes, host cells capable of expressing the engineered HHDH enzymes, and methods of using the engineered HHDH enzymes to synthesize a variety of chiral compounds including chiral epoxides and chiral alcohols.
    Type: Application
    Filed: December 18, 2009
    Publication date: July 8, 2010
    Applicant: CODEXIS, INC.
    Inventors: Erik De Vries, Louis Clark, Scott McVicar, Erika Segraves, Shiwei Song, Kheng Lin Tan