Patents by Inventor Shiyi Zhang
Shiyi Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11976607Abstract: An engine includes a cylinder head and a cylinder block. The cylinder head has a first water jacket passage, an exhaust passage and a second water jacket passage. The exhaust passage is located between the first water jacket passage and the second water jacket passage. The first water jacket passage and the second water jacket passage are disposed close to the exhaust passage. The first water jacket passage is in communication with the second water jacket passage. The second water jacket passage is in communication with the cylinder block. The second water jacket passage has a water inlet passage.Type: GrantFiled: June 26, 2023Date of Patent: May 7, 2024Assignee: BYD COMPANY LIMITEDInventors: Mingliang Liu, Nan Zhang, Shiyi Pan, Shengjie Hao, Bingbing Yuan
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Patent number: 11975602Abstract: An engine includes an engine water jacket, a water pump and a thermostat assembly. The engine water jacket, the thermostat assembly and the water pump are connected to form a circulation passage. The thermostat assembly is connected between the engine water jacket and the water pump. The engine water jacket includes a cylinder head water jacket and a cylinder block water jacket. The thermostat assembly is configured to enable the coolant to enter the cylinder head water jacket of the cylinder head water jacket and the cylinder block water jacket upon cold start.Type: GrantFiled: June 27, 2023Date of Patent: May 7, 2024Assignee: BYD COMPANY LIMITEDInventors: Jing Liu, Nan Zhang, Shiyi Pan, Fanchao Meng, Mingliang Liu
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Publication number: 20240136836Abstract: A charger including a vertical section including a first surface, the first surface facing a front direction and including an attachment portion configured to a receive a battery pack, and a horizontal section configured to protrude, in the front direction, from a bottom portion of the vertical section. The charger further including a second surface disposed on the horizontal section, the second surface facing an upward direction, and a fan disposed proximate the horizontal surface, the fan configured to cool the battery pack.Type: ApplicationFiled: October 20, 2022Publication date: April 25, 2024Inventors: Ece Polat, Adam Zwilling, Nicolas James Hanks, Shiyi Zhang, Krishna Sai Teja Kalavala
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Patent number: 11952957Abstract: An engine includes a cylinder block, a cylinder head, and a piston. The cylinder head is connected to the cylinder block. The piston is movably connected to the cylinder block. The cylinder block, the cylinder head, and the piston form a combustion chamber. The cylinder head includes an intake valve hole and an exhaust valve hole. An intake valve is disposed at the intake valve hole and an exhaust valve is disposed at the exhaust valve hole. A barrier protrusion is protruded at the edge of the intake valve hole away from the exhaust valve hole. The included angle between a first connecting line connecting a first end of the barrier protrusion and a center of the intake valve hole and a second connecting line connecting a second end of the barrier protrusion and the center of the intake valve hole is greater than 120 degrees and less than or equal to 180 degrees.Type: GrantFiled: June 26, 2023Date of Patent: April 9, 2024Assignee: BYD COMPANY LIMITEDInventors: Qiang Wang, Nan Zhang, Shiyi Pan, Shuguang Zhang, Peng Guo
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Publication number: 20240108633Abstract: A JAK inhibitor may be used in preparation of a medicament. The medicament may be used for preventing and/or treating a disease or condition associated with an antitumor agent in a subject. A pharmaceutical composition may include the JAK inhibitor as may a kit. The JAK inhibitor may include a compound of formula (I) or a pharmaceutically acceptable salt thereof: Q, X, Y, and Z being independently N or C, and R1, R2 and R3 being independently a 5-6-membered aromatic ring, 5-6-membered heteroaromatic ring, 5-6-membered cycloalkyl, 5-6-membered heterocycloalkyl, amino, or amido, the aromatic ring, heteroaromatic ring, cycloalkyl, and/or heterocycloalkyl being optionally substituted by a substituent.Type: ApplicationFiled: December 28, 2021Publication date: April 4, 2024Applicant: ONQUALITY PHARMACEUTICALS CHINA LTD.Inventors: Wenxi LI, Shiyi ZHANG, Qing YOU, Linan YANG, Zhaoyu WU
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Publication number: 20240052964Abstract: A flexible adaptive large length to thin ratio pipeline intelligent repair device is provided. The walking mechanism includes a walking bracket and a radius adjustment assembly. The radius adjustment assembly is located in the middle of the walking bracket. The first motor for driving the radius adjustment assembly is set in the middle of the walking mechanism, and the second motor for driving the movement of the walking bracket is set on the walking bracket. The ends of several groups of connecting rods are removably connected to the working part, which includes the pre-welding sandblasting mechanism, the heating mechanism and the welding repair mechanism. A positioning sensor is set on the walking bracket. The variable-diameter all-position intelligent pipe internal repair device can integrate pre-welding cleaning, preheating, welding repair and post-welding heat treatment.Type: ApplicationFiled: April 12, 2023Publication date: February 15, 2024Applicant: Nanchang Hangkong UniversityInventors: Timing ZHANG, Yuhua CHEN, Jiaxing GUO, Shiyi ZHANG, Shanlin WANG, Jilin XIE, Limeng YIN, Yanlin JIA, Zhikang YE
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Publication number: 20230405003Abstract: The present application relates to a thymidine derivative, or use of a uridine derivative in combination with a thymidine derivative in preparation of a drug for preventing or treating a disease or disorder associated with administration of a chemotherapeutical drug in a subject. The present application further provides a method of preventing or treating a disease or disorder associated with administration of a chemotherapeutical drug in a subject comprising administering a prophylactically or therapeutically effective amount of a thymidine derivative or uridine and thymidine derivatives to a subject in need thereof.Type: ApplicationFiled: October 29, 2021Publication date: December 21, 2023Applicant: ONQUALITY PHARMACEUTICALS CHINA LTD.Inventors: Shiyi ZHANG, Zhaoyu WU, Shilan LIU
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Patent number: 11742665Abstract: A power margin tracking control method and system for a multi-terminal high-voltage direct current converter station are provided. A power adjustment factor is introduced on the basis of a droop coefficient, to realize a self-adaptive regulation of a converter station operation mode to a real-time fluctuation of a wind and solar power. In this way, the system operation stability and the power fluctuation allocation capability in a grid-connected system are improved. Furthermore, a DC voltage deviation in the multi-terminal high-voltage direct current grid is reduced.Type: GrantFiled: July 29, 2021Date of Patent: August 29, 2023Assignee: NORTH CHINA ELECTRIC POWER UNIVERSITYInventors: Ming Zhou, Shiyi Zhang, Gengyin Li
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Publication number: 20230039421Abstract: Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.Type: ApplicationFiled: June 9, 2022Publication date: February 9, 2023Applicants: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.Inventors: Andrew Bellinger, Shiyi Zhang, Carlo Giovanni Traverso, Robert S. Langer, Stacy Mo, Tyler Grant, Mousa Jafari, Dean Liang Glettig, Angela DiCiccio, Lowell L. Wood, JR., Philip A. Eckhoff
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Publication number: 20220411424Abstract: The present disclosure relates to complexes comprising caffeine and tannic acid as well as emulsions and beverages comprising these complexes which slow the release of the caffeine. Also described are methods of preparing the complexes and emulsions and beverages comprising caffeine-tannic acid complexes.Type: ApplicationFiled: June 17, 2022Publication date: December 29, 2022Inventors: Yu WANG, DaSom NO, Yuan FANG, Nelson TRUSLER, Damian BROWNE, George MEYER, Xin ZHAO, Meng TIAN, Shiyi ZHANG
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Publication number: 20220401449Abstract: The present disclosure relates to colloids comprising caffeine-tannic acid complexes which slow the release of the caffeine. Also described are methods of preparing the colloids and beverages comprising colloids comprising caffeine-tannic acid complexes.Type: ApplicationFiled: June 17, 2022Publication date: December 22, 2022Inventors: Yu WANG, DaSom NO, Yuan FANG, Nelson TRUSLER, Damian BROWNE, Xin ZHAO, Meng TIAN, Shiyi ZHANG, George MEYER, Rohil BHATNAGAR
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Publication number: 20220233583Abstract: A method for treating or preventing saccharide-related diseases or disorders, comprising administering a therapeutically or prophylactically effective amount of a polymer comprising at least one boronic acid group to a subject having or at risk of having a saccharide-related disease or disorder.Type: ApplicationFiled: June 3, 2020Publication date: July 28, 2022Inventors: Shiyi ZHANG, Xin ZHAO, Meng TIAN, Bingxue YANG, Songxuan SUN, Huijun ZHANG
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Patent number: 11389399Abstract: Certain embodiments comprise administering a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance, and, optionally, a linker. In some such embodiments, the linker may be configured to degrade.Type: GrantFiled: December 18, 2020Date of Patent: July 19, 2022Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.Inventors: Andrew Bellinger, Shiyi Zhang, Carlo Giovanni Traverso, Robert S. Langer, Stacy Mo, Tyler Grant, Mousa Jafari, Dean Liang Glettig, Angela DiCiccio, Lowell L. Wood, Jr., Philip A. Eckhoff
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Patent number: 11357723Abstract: Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.Type: GrantFiled: February 12, 2021Date of Patent: June 14, 2022Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.Inventors: Andrew Bellinger, Shiyi Zhang, Carlo Giovanni Traverso, Robert S. Langer, Stacy Mo, Tyler Grant, Mousa Jafari, Dean Liang Glettig, Angela DiCiccio, Lowell L. Wood, Jr., Philip A. Eckhoff
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Patent number: 11246829Abstract: Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.Type: GrantFiled: June 11, 2020Date of Patent: February 15, 2022Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.Inventors: Andrew Bellinger, Shiyi Zhang, Carlo Giovanni Traverso, Robert S. Langer, Stacy Mo, Tyler Grant, Mousa Jafari, Dean Liang Glettig, Angela DiCiccio, Lowell L. Wood, Jr., Philip A. Eckhoff
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Publication number: 20220029422Abstract: A power margin tracking control method and system for a multi-terminal high-voltage direct current converter station are provided. A power adjustment factor is introduced on the basis of a droop coefficient, to realize a self-adaptive regulation of a converter station operation mode to a real-time fluctuation of a wind and solar power. In this way, the system operation stability and the power fluctuation allocation capability in a grid-connected system are improved. Furthermore, a DC voltage deviation in the multi-terminal high-voltage direct current grid is reduced.Type: ApplicationFiled: July 29, 2021Publication date: January 27, 2022Applicant: NORTH CHINA ELECTRIC POWER UNIVERSITYInventors: MING ZHOU, SHIYI ZHANG, GENGYIN LI
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Patent number: 11173433Abstract: The present disclosure provides a service life reminding system for a water bottle filter element. The service life reminding system for the water bottle filter element includes a one-way valve head, a mounting bracket, and a circuit board. The mounting bracket includes a first accommodating cavity. A portion of the one-way valve head is movably accommodated in the first accommodating cavity. A magnetic element is fixed in the mounting bracket. A magnetic sensor is arranged on the circuit board. Both of the circuit board and the magnetic sensor are accommodated in the one-way valve head. When the one-way valve head slides to abut against the mounting bracket, the magnetic sensor senses the magnetic element. When the one-way valve head slides away from the mounting bracket until the one-way valve head separates from the mounting bracket, the magnetic sensor is unable to sense the magnetic element.Type: GrantFiled: January 11, 2021Date of Patent: November 16, 2021Assignee: SHENZHEN SHENLAN ELECTRIC APPLIANCE CO., LTDInventors: Tianxiong Zeng, Weifu Guo, Shiyi Zhang
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Publication number: 20210322361Abstract: The present application relates to use of a nitric oxide releasing agent in the preparation of a medicament for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor. The present application further provides a method for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor in a subject. The mothed comprise administering, to a subject in need, a prophylactically or therapeutically effective amount of the nitric oxide releasing agent.Type: ApplicationFiled: March 29, 2021Publication date: October 21, 2021Inventors: Shiyi Zhang, Zhaoyu Wu, Chao Liu, Linan Yang, Leying Chen, Jie Luo
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Patent number: D1010305Type: GrantFiled: December 18, 2020Date of Patent: January 9, 2024Assignee: The ERGO Baby Carrier, Inc.Inventors: Rodney V. Telford, Shiyi Zhang
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Patent number: D1024541Type: GrantFiled: June 19, 2020Date of Patent: April 30, 2024Assignee: The ERGO Baby Carrier, Inc.Inventors: Rodney V. Telford, Shiyi Zhang