Patents by Inventor Shiying SONG

Shiying SONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing a porcine-derived interferon-delta 5 and application of porcine-derived interferon-delta 5
    Patent number: 11965010
    Abstract: Disclosed are a method for preparing a porcine-derived interferon-delta 5 (pIFN-?5) and an application of the pIFN-?5, where the method for preparing pIFN-?5 includes the following steps: step S1, obtaining a DNA fragment containing pIFN-?5 gene through reverse transcription-polymerase chain reaction (RT-PCR) amplification by using the total RNA of pretreated porcine small intestinal epithelial cells IPEC-J2; step S2, inserting the DNA fragment containing pIFN-?5 gene into an exogenous expression vector to construct a recombinant expression vector for expressing the pIFN-?5 gene; and step S3, introducing the recombinant expression vector into a suitable host cell, and driving the host cell to express the pIFN-?5 gene to obtain the pIFN-?5. The recombinant pIFN-?5 protein is used to prepare drugs or preparations for inhibiting infection of porcine epidemic diarrhea virus (PEDV), porcine transmissible gastroenteritis virus (TGEV), porcine delta coronavirus (PDCoV) and porcine rotavirus (PRoV).
    Type: Grant
    Filed: April 27, 2023
    Date of Patent: April 23, 2024
    Assignee: JIANGSU ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Baochao Fan, Bin Li, Shiying Song, Xuehan Zhang, Xuejiao Zhu, Jinzhu Zhou, Yongxiang Zhao, Jizong Li, Rongli Guo, Weilu Guo, Xue Zhang
  • METHOD FOR PREPARING A PORCINE-DERIVED INTERFERON-DELTA 5 AND APPLICATION OF PORCINE-DERIVED INTERFERON-DELTA 5
    Publication number: 20230303651
    Abstract: Disclosed are a method for preparing a porcine-derived interferon-delta 5 (pIFN-?5) and an application of the pIFN-?5, where the method for preparing pIFN-?5 includes the following steps: step S1, obtaining a DNA fragment containing pIFN-?5 gene through reverse transcription-polymerase chain reaction (RT-PCR) amplification by using the total RNA of pretreated porcine small intestinal epithelial cells IPEC-J2; step S2, inserting the DNA fragment containing pIFN-?5 gene into an exogenous expression vector to construct a recombinant expression vector for expressing the pIFN-?5 gene; and step S3, introducing the recombinant expression vector into a suitable host cell, and driving the host cell to express the pIFN-?5 gene to obtain the pIFN-?5. The recombinant pIFN-?5 protein is used to prepare drugs or preparations for inhibiting infection of porcine epidemic diarrhea virus (PEDV), porcine transmissible gastroenteritis virus (TGEV), porcine delta coronavirus (PDCoV) and porcine rotavirus (PRoV).
    Type: Application
    Filed: April 27, 2023
    Publication date: September 28, 2023
    Inventors: Baochao FAN, Bin LI, Shiying SONG, Xuehan ZHANG, Xuejiao ZHU, Jinzhu ZHOU, Yongxiang ZHAO, Jizong LI, Rongli GUO, Weilu GUO, Xue ZHANG