Abstract: Apparatuses, systems, and methods are provided for automatically selecting first and last frames for a sequence of frames from which an accumulation contrast image may be generated. In some examples, statistical distributions of groups of pixels of the image frames may be analyzed to generate parametric maps. The parametric maps may be analyzed to select the first and last image frames of the sequence. In some examples, an image frame corresponding to the parametric map having a value above a threshold value may be selected as a first frame. In some examples, an image frame corresponding to the parametric map having a maximum value of all the parametric maps may be selected as the last frame. In some examples, the parametric maps may be used to segment features, such as a tumor, from the image frame.

Abstract: An ultrasound imaging system may analyze motion of landmarks in a temporal sequence of image frames to determine mobility of one or more landmarks. In some examples, the sequence of image frames may be analyzed by one or more artificial intelligence models to detect landmarks and generate flow fields for the detected landmarks. The flow fields may be analyzed to determine the isotropy of the movement of the landmarks. The isotropy analysis may be used to generate a quantitative mobility index.

Abstract: A system for visualization and quantification of ultrasound imaging data may include a display unit, and a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to generate vector field data corresponding to the fluid flow, wherein the vector field data comprises axial and lateral velocity components of the fluid, extract spatiotemporal information from the vector field data at one or more user-selected points within the image, and cause the display unit to concurrently display the spatiotemporal information at the one or more user-selected points with the image including a graphical representation of the vector field data overlaid on the image, wherein the spatiotemporal information includes at least one of a magnitude and an angle of the fluid flow.

Abstract: An ultrasound imaging system may acquire short and/or undersampled radiofrequency ensembles for generating color Doppler images. The ultrasound imaging system may process the short and/or undersampled ensembles to simulate color Doppler images acquired from long radiofrequency ensembles. In some examples, the ultrasound imaging system may include a neural networks to process the ensembles. In some examples, the neural network may include two serial neural networks. In some examples, during training of the neural network, a power Doppler-based flow mask may be used on the output of the neural network. In some examples, during training of the neural network, an adversarial loss may be used on the output of the neural network.

Abstract: A system for visualization and quantification of ultrasound imaging data may include a display unit, and a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to generate vector field data corresponding to the fluid flow, wherein the vector field data comprises axial and lateral velocity components of the fluid, extract spatiotemporal information from the vector field data at one or more user-selected points within the image, and cause the display unit to concurrently display the spatiotemporal information at the one or more user-selected points with the image including a graphical representation of the vector field data overlaid on the image, wherein the spatiotemporal information includes at least one of a magnitude and an angle of the fluid flow.

Abstract: A system for visualization and quantification of ultrasound imaging data according to embodiments of the present disclosure may include a display unit, and a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to estimate axial and lateral velocity components of the fluid flowing within the bodily structure, determine a plurality of flow directions within the image based on the axial and lateral velocity components, differentially encode the flow directions based on flow direction angle to generate a flow direction map, and cause the display unit to concurrently display the image including the bodily structure overlaid with the flow direction map.

Abstract: Systems and methods for multi-level vascular imaging for construction and display of vasculature from large to small vessels and micro-vessels using a combination of varying resolution contrast enhanced ultrasound flow imaging modalities are disclosed. While one or more resolution flow imaging modes may be employed for imaging large to small vessels of a vascular tree within a large region of interest, a high resolution mode, such as super resolution imaging, constructed for delineation of the microvascular morphology and directional microcirculation is provided within one or more small ROIs placed in selected locations within the larger ROI.

Abstract: Systems and methods for generating adaptive contrast accumulation imaging images are disclosed. A point spread function thinning/skeletonization technique may be performed on contrast enhanced image frames. An aggressiveness parameter of the technique may be adapted temporally and/or spatially. The aggressiveness parameter may be adapted based on various factors, including, but not limited to, time since injection of the contrast agent, signal intensity, and/or vessel size. The images may be temporally accumulated to generate a final sequence of adaptive contrast accumulation imaging images.

Abstract: A system for visualization and quantification of ultrasound imaging data according to embodiments of the present disclosure may include a display unit, and a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to estimate axial and lateral velocity components of the fluid flowing within the bodily structure, determine a plurality of flow directions within the image based on the axial and lateral velocity components, differentially encode the flow directions based on flow direction angle to generate a flow direction map, and cause the display unit to concurrently display the image including the bodily structure overlaid with the flow direction map.

Abstract: Systems and methods for time-varying two-dimensional (2D) color maps for visualizing images or sequences of images are disclosed. The 2D color map may include brightness values of a hue corresponding to different intensities that changes over time. In some 2D color maps, the hue used for the intensity scale may change over time while the brightness of a pixel may not. In some 2D color maps, both the hue and the brightness may change relative to intensity over time.

Abstract: A system according to the present disclosure may include a display unit, a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to generate vector field data including axial and lateral (or transverse) velocity components of the fluid flowing within the bodily structure, calculate velocity profiles for a plurality of locations along a wall of the bodily structure based on the axial and lateral velocity components, generate wall shear stress (WSS) visualization data based, at least in part, on the velocity profiles, and cause the display unit to concurrently display the image including the bodily structure overlaid with the WSS visualization data.

Abstract: An apparatus can be used to generate acoustic imaging pulse sequences and receive corresponding echoes elicited by the acoustic imaging pulse sequences. An acoustic radiation force (ARF) pulse sequence can be generated to agitate a contrast medium in a tissue region between the acoustic imaging pulse sequences. A decorrelation between images corresponding to the received echoes can be determined. A weighting map can be applied to an image to weight a region of the image corresponding to a spatial location of the contrast medium using the determined decorrelation. In an example, the receiving of corresponding echoes elicited by the acoustic imaging pulse sequences can include receiving acoustic energy having a range of frequencies offset from a fundamental frequency associated with the acoustic imaging pulse sequences. An acoustic imaging pulse sequence can include a pulse having an inverted amplitude envelope with respect to another pulse included in the sequence.

Abstract: An ultrasonic diagnostic imaging system acquires volume image flow data sets of subvolumes of a blood vessel over at least a cardiac cycle. Image data of the subvolumes is then aligned both spatially and temporally to produce 3D images of the volume flow of the blood vessel over a heart cycle. A volume flow profile curve is produced from the acquired volume image flow data sets. The subvolumes are scanned starting with the center of the blood vessel and proceeding outward therefrom. The blood vessel center may be designated manually by a user or automatically by the ultrasound system by Doppler or other methods. Each subvolume is scanned over a heart cycle, with the systolic phase in the temporal center of the acquisition interval. The subvolumes are scanned in synchronism with the heart cycle and the estimation of a heart cycle is updated during each subvolume data acquisition interval.

Abstract: The invention provides an ultrasound data processing method for pre-processing signal data in advance of generating ultrasound images. The method seeks to reduce noise through application of coherent persistence to a series of raw ultrasound signal representations representative of the same path or section through a body but at different successive times. A motion compensation procedure including amplitude peak registration and phase alignment is applied to raw echo signal data in advance of application of persistence in order to cohere the signals and thereby limit the introduction of motion induced artifacts.

Abstract: The present disclosure describes ultrasound systems configured to perform microbubble-based contrast imaging with enhanced sensitivity. The systems can enhance echo signals derived from microbubbles while suppressing echo signals derived from tissue by detecting phase shifts exhibited by microbubbles in resonance. To detect the phase shifts, and thereby distinguish between microbubble-based signals and tissue-based signals, the systems can transmit a series of ultrasound pulses into a target region in accordance with a predefined sequence. The sequence can include an initiation pulse configured to stimulate microbubbles into nonlinear oscillation, a detection pulse configured to detect the nonlinear oscillation, and a summation pulse formed by transmitting an initiation pulse and detection pulse with a small time delay therebetween.

Abstract: Systems and methods for visualizing microbubbles for contrast-enhanced imaging are described herein. Microbubbles may be visualized by multi-pixel spots by identifying and localizing individual microbubbles. Motion compensation may be provided for localized microbubbles or for contrast images prior to microbubble identification and localization. Users may determine the size of the multi-pixel spot by adjusting a filter, for example, adjusting a threshold value of the filter. Altering the size of the multi-pixel spot may alter the resolution. As the number of pixels increases, the resolution decreases, but the acquisition time may also decrease. As the number of pixels decreases, the resolution increases, but the acquisition time may increase.

Abstract: The present disclosure describes ultrasound systems configured to enhance flow imaging and analysis by adaptively adjusting one or more imaging parameters in response to acquired flow measurements. Example systems can include an ultrasound transducer and one or more processors. Using the system components, mean flow velocity magnitude and acceleration can be determined within a target region during an acquisition phase, which may include a cardiac cycle. One or more adjusted flow imaging parameters, such as adjusted ensemble length, temporal smoothing filter length and/or step size, can be determined based on the acquired flow measurements to increase the signal quality of newly acquired ultrasound echo signals. The adjusted flow imaging parameters can then be applied by the ultrasound transducer during a second acquisition phase.

Abstract: An ultrasound system produces high quality images at a high framerate of display. A plane or volume to be imaged is scanned by different diverging transmit beams to acquire a series of different sub-frames, the number of sub-frame acquisitions comprising a total number of transmit beams which would produce a high quality image. The echoes received in response to the transmit beams of a sub-frame are coherently combined with the echoes received in other sub-frames. Each time the echoes of a new sub-frame have been coherently combined with the echoes of all other different sub-frames, a full image is produced. After a complete series of sub-frames has been received and the echoes combined, another series of sub-frame acquisition is commenced and a new series of sub-frames acquired. As each new sub-frame is acquired, it is coherently combined with all the other different and most recently acquired sub-frames.

Abstract: A system for visualization and quantification of ultrasound imaging data according to embodiments of the present disclosure may include a display unit, and a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to estimate axial and lateral velocity components of the fluid flowing within the bodily structure, determine a plurality of flow directions within the image based on the axial and lateral velocity components, differentially encode the flow directions based on flow direction angle to generate a flow direction map, and cause the display unit to concurrently display the image including the bodily structure overlaid with the flow direction map.

Abstract: A system for visualization and quantification of ultrasound imaging data may include a display unit, and a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to generate vector field data corresponding to the fluid flow, wherein the vector field data comprises axial and lateral velocity components of the fluid, extract spatiotemporal information from the vector field data at one or more user-selected points within the image, and cause the display unit to concurrently display the spatiotemporal information at the one or more user-selected points with the image including a graphical representation of the vector field data overlaid on the image, wherein the spatiotemporal information includes at least one of a magnitude and an angle of the fluid flow.