Patents by Inventor Shiyou ZHU

Shiyou ZHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240076690
    Abstract: A group of viral vectors including: first viral vector, wherein first viral vector carries first nucleic acid molecule, and the first nucleic acid molecule encodes envelope protein; second viral vector, wherein second viral vector carries second nucleic acid molecule, the second nucleic acid molecule encodes fusion protein, the fusion protein includes single-chain antibody and C-terminal domain of envelope protein, the C-terminal domain of envelope protein includes transmembrane region and intracellular region of envelope protein, the C-terminus of single-chain antibody connects with N-terminus of C-terminal domain of envelope protein, the single-chain antibody targets a specific antigen; first nucleic acid molecule and second nucleic acid molecule are arranged to express envelope protein and fusion protein, and the envelope protein and the fusion protein are in non-fusion form.
    Type: Application
    Filed: September 29, 2021
    Publication date: March 7, 2024
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Xiaodan YANG, Shiyou CHEN, Xiuqin ZHU, Junji DONG, Xiaofeng CHEN, Wenjia LI
  • Publication number: 20230365962
    Abstract: The present application provides methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA. The present application further provides deaminase-recruiting RNAs used in the RNA editing methods and compositions and kits comprising the same.
    Type: Application
    Filed: April 19, 2023
    Publication date: November 16, 2023
    Inventors: Wensheng Wei, Zongyi Yi, Liang Qu, Feng Tian, Chunhui Wang, Shiyou Zhu, Zhuo Zhou
  • Patent number: 11702658
    Abstract: The present application provides methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA. The present application further provides deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Grant
    Filed: October 14, 2021
    Date of Patent: July 18, 2023
    Assignees: EDIGENE THERAPEUTICS (BEIJING) INC., PEKING UNIVERSITY
    Inventors: Pengfei Yuan, Yanxia Zhao, Nengyin Liu, Zexuan Yi, Gangbin Tang, Wensheng Wei, Liang Qu, Zongyi Yi, Shiyou Zhu, Chunhui Wang, Zhongzheng Cao, Zhuo Zhou
  • Patent number: 11661596
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA, deaminase-recruiting RNAs used in the RNA editing methods, compositions and kits comprising the same.
    Type: Grant
    Filed: January 11, 2022
    Date of Patent: May 30, 2023
    Assignee: PEKING UNIVERSITY
    Inventors: Wensheng Wei, Zongyi Yi, Liang Qu, Feng Tian, Chunhui Wang, Shiyou Zhu, Zhuo Zhou
  • Publication number: 20220307020
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA. Further provided are deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Application
    Filed: April 15, 2020
    Publication date: September 29, 2022
    Inventors: Pengfei YUAN, Yanxia ZHAO, Nengyin LIU, Zexuan YI, Gangbin TANG, Wensheng WEI, Liang QU, Zongyi YI, Shiyou ZHU, Chunhui WANG, Zhongzheng CAO, Zhuo ZHOU
  • Publication number: 20220243194
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA, deaminase-recruiting RNAs used in the RNA editing methods, compositions and kits comprising the same.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 4, 2022
    Applicant: PEKING UNIVERSITY
    Inventors: Wensheng WEI, Zongyi YI, Liang QU, Feng TIAN, Chunhui WANG, Shiyou ZHU, Zhuo ZHOU
  • Publication number: 20220135963
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA, deaminase-recruiting RNAs used in the RNA editing methods, compositions and kits comprising the same.
    Type: Application
    Filed: January 11, 2022
    Publication date: May 5, 2022
    Applicant: PEKING UNIVERSITY
    Inventors: Wensheng WEI, Zongyi YI, Liang QU, Feng TIAN, Chunhui WANG, Shiyou ZHU, Zhuo ZHOU
  • Publication number: 20220098587
    Abstract: The present application provides methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA. The present application further provides deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Application
    Filed: October 14, 2021
    Publication date: March 31, 2022
    Inventors: Pengfei YUAN, Yanxia ZHAO, Nengyin LIU, Zexuan YI, Gangbin TANG, Wensheng WEI, Liang QU, Zongyi YI, Shiyou ZHU, Chunhui WANG, Zhongzheng CAO, Zhuo ZHOU
  • Publication number: 20220064633
    Abstract: Compositions, kits and methods are provided for genetic screening using one or more sets of guide RNA constructs having internal barcodes (“iBAR”). Each set has three or more guide RNA constructs targeting the same genomic locus, but embedded with different iBAR sequences.
    Type: Application
    Filed: December 20, 2019
    Publication date: March 3, 2022
    Applicants: Peking University, Edigene Biotechnology Inc.
    Inventors: Wensheng WEI, Shiyou ZHU, Zhongzheng CAO, Zhiheng LIU, Yuan HE, Pengfei YUAN
  • Publication number: 20210355494
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA, and deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Application
    Filed: October 12, 2019
    Publication date: November 18, 2021
    Inventors: Wensheng WEI, Liang QU, Zongyi YI, Shiyou ZHU, Chunhui WANG, Zhongzheng CAO, Zhuo ZHOU, Pengfei YUAN
  • Publication number: 20210310026
    Abstract: Provided are methods for editing RNA by introducing a deaminase-recruiting RNA in a host cell for deamination of an adenosine in a target RNA, and deaminase-recruiting RNAs used in the RNA editing methods and compositions comprising the same.
    Type: Application
    Filed: April 9, 2021
    Publication date: October 7, 2021
    Inventors: Wensheng WEI, Liang QU, Zongyi YI, Shiyou ZHU, Chunhui WANG, Zhongzheng CAO, Zhuo ZHOU, Pengfei YUAN