Patents by Inventor Shiyu Chen

Shiyu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240274302
    Abstract: Disclosed are a system and method of predicting sensitivity of Klebsiella against MeropeneM, which belong to bioinformatics art. The system comprises a computer readable storage medium on which is stored a computer program. An Exp (?k) power value calculation method is implemented when said computer program is executed by a processor. Said Exp(?k) power value calculation method comprises following computing steps: S1: k value is calculated according to formula I: Formula ? I ? - 1.44 + 0. ? × ( ? ? ) - 0.66 × ( ? ? ) + 0. ? × ( ? ? ) + 3.04 ? × ( ? ? ) - 0.46 × ( ? ? ) ? indicates text missing or illegible when filed S2: Exp(?k) power value with natural constant e as base and ?k as exponent is calculated; wherein, C1-C5 are respectively the number of mphA, marA, Klebsiella pneumoniae KpnE, KPC-1, floR gene copies in the candidate Klebsiella strain.
    Type: Application
    Filed: November 29, 2023
    Publication date: August 15, 2024
    Inventors: Qiwen Yang, Jing CHEN, Wei Yu, Jun Wang, Xiaobing Chu, Shiyu Chen, Qian Zhang, Yao Yao
  • Patent number: 12062414
    Abstract: A system and a method for predicting susceptibility of genus Klebsiella to amikacin are provided. The system includes a calculating unit containing a computer-readable storage medium stored with a computer program; the computer program is used to, when is executed by a processor, implement a calculation method for an Exp(?k) power value, and the calculation method for the Exp(?k) power value includes: step 1, calculating a k value according to formula I; and step 2, calculating the Exp(?k) power value with an Euler's constant e as a base and a ?k value as an exponential; and C1 to C5 are respectively copy numbers of an arr-2 gene, an acrB gene, an armA gene, an oqxB gene, and a rmtB gene in to-be-predicted Klebsiella strains. When the method and the system are adopted to predict the susceptibility of the genus Klebsiella to amikacin, an accuracy rate is about 98.8%.
    Type: Grant
    Filed: November 15, 2023
    Date of Patent: August 13, 2024
    Assignees: Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Hangzhou Matridx Biotechnology Co Ltd
    Inventors: Qiwen Yang, Jing Chen, Wei Yu, Jun Wang, Xiaobing Chu, Shiyu Chen, Qian Zhang, YiQun Mi
  • Publication number: 20240265995
    Abstract: Disclosed are a system and method of predicting sensitivity of Klebsiella against Cefoxitin, which belong to bioinformatics art. The system comprises a computer readable storage medium on which is stored a computer program. An Exp (?k) power value calculation method is implemented when the computer program is executed by a processor. The Exp(?k) power value calculation method comprises following computing steps: S1: k value is calculated according to formula I: k = 0.032 - 0.557 × ( C ? 1 - 1.008 0.317 ) + 0.054 × ( C ? 2 - 0.667 1.326 ) + 2.878 × ( C ? 3 - 0.552 1.121 ) + 1.021 × ( C ? 4 - 0.072 0.377 ) + 0.772 × ( C ? 5 - 0.036 0.292 ) Formula ? I S2: Exp(?k) power value with natural constant e as base and ?k as exponent is calculated; wherein, C1-C5 are respectively the number of ramA, sul1, KPC-1, DHA-1, bleomycin resistance determinant gene copies in the candidate Klebsiella strain.
    Type: Application
    Filed: November 29, 2023
    Publication date: August 8, 2024
    Inventors: Qiwen Yang, Jing CHEN, Wei YU, Jun WANG, Xiaobing CHU, Shiyu CHEN, Qian ZHANG, Yao YAO
  • Publication number: 20240265994
    Abstract: A system and a method for predicting susceptibility of genus klebsiella to amikacin are provided. The system includes a calculating unit containing a computer-readable storage medium stored with a computer program; the computer program is used to, when is executed by a processor, implement a calculation method for an Exp(?k) power value, and the calculation method for the Exp(?k) power value includes: step 1, calculating a k value according to formula I; and step 2, calculating the Exp(?k) power value with an Euler's constant e as a base and a ?k value as an exponential; and C1 to C5 are respectively copy numbers of an arr-2 gene, an acrB gene, an armA gene, an oqxB gene, and a rmtB gene in to-be-predicted klebsiella strains. When the method and the system are adopted to predict the susceptibility of the genus klebsiella to amikacin, an accuracy rate is about 98.8%.
    Type: Application
    Filed: November 15, 2023
    Publication date: August 8, 2024
    Inventors: Qiwen Yang, Jing Chen, Wei Yu, Jun Wang, Xiaobing Chu, Shiyu Chen, Qian Zhang, YiQun Mi
  • Publication number: 20240205298
    Abstract: A method for processing a session message and apparatus, a device, a storage medium, and a program product. The method includes displaying at least two session messages, the at least two session messages comprising a first session message and a second session message, receiving a message merging instruction, the message merging instruction being configured to instruct merging the first session message and the second session message and displaying, based on the message merging instruction, a third session message obtained by merging the first session message and the second session message.
    Type: Application
    Filed: March 4, 2024
    Publication date: June 20, 2024
    Applicant: Tencent Technology (Shenzhen) Company Limited
    Inventors: Sha Sha, Liqiang Liu, Shiyu Chen, Longwu Jiang, Yulin Shen, Xianmin Xiao
  • Publication number: 20230362333
    Abstract: A data processing method and apparatus, a device, and a readable storage medium are provided. The method includes: performing figure acquisition on a first object in response to a login operation on an application client, and displaying a first virtual object associated with an acquired object figure of the first object (S101); displaying, in a case that a virtual conversation space is entered by using the first virtual object, one or more virtual objects in the virtual conversation space, the one or more virtual objects including the first virtual object, and a space figure of the virtual conversation space being associated with the one or more virtual objects (S102); and displaying a conversation message corresponding to each of the one or more virtual objects in the virtual conversation space (S103). A virtual object in an application is displayed efficiently in a diversified manner, and virtual object display modes are enriched.
    Type: Application
    Filed: July 13, 2023
    Publication date: November 9, 2023
    Applicant: Tencent Technology (Shenzhen) Campany Limited
    Inventors: Shu-Hui CHOU, Xianmin XIAO, Shiyu CHEN, Caijun WANG, Longwu JIANG, Liqiang LIU, Qinghua ZHONG
  • Publication number: 20230183524
    Abstract: The present disclosure relates to the technical field of batteries, and specifically relates to a polyamine composite material and a preparation method therefor, a slurry, a separator, an electrode sheet, and a lithium-sulfur battery containing the same. The polyamine composite material comprises a carboxylated carbon-based material serving as a substrate and a polyamine serving as an outer surface layer, and the polyamine is uniformly and smoothly coated on the outer side surface and/or the inner pore surface of the carboxylated carbon-based material. The material is rich in amino groups and is uniform and stable, can be used in the lithium-sulfur battery, and can effectively adsorb lithium polysulfide during a long cycle process.
    Type: Application
    Filed: December 29, 2020
    Publication date: June 15, 2023
    Inventors: Weishan LI, Zhibin JIANG, Lidan XING, Youhao LIAO, Shiyu CHEN, Xiying JIAN, Jinxia HUANG
  • Publication number: 20230158069
    Abstract: The present invention discloses an application of TREM2hi macrophages in preparation of drugs for treating cardiac dysfunction, and belongs to the technical field of medicine. The present invention discloses for the first time that there is a kind of macrophage subsets for high expression of a triggering receptor expressed on myeloid cells-2 in cardiac derived macrophages, which has a strong function of recognizing and reducing mitochondrial damage and plays an important role in maintaining a cardiac metabolic balance. Therefore, the TREM2hi macrophages have important application value in treatment of the cardiac dysfunction.
    Type: Application
    Filed: November 6, 2022
    Publication date: May 25, 2023
    Inventors: XIANGMING FANG, KAI ZHANG, SHIYU CHEN, JIALI MAO, YANG WANG
  • Patent number: 11651760
    Abstract: A simulation test system and method for vehicle road noise cancellation (RNC) are provided in one or more embodiments of the present disclosure. The simulation test system may include a vehicle RNC simulation system and a power amplifier. The vehicle RNC simulation system is configured to simulate an RNC system in a vehicle environment. The power amplifier is configured to execute an RNC algorithm and may perform data communication with the vehicle RNC simulation system. The vehicle RNC simulation system transmits acceleration data representing an acceleration signal and microphone data representing a microphone signal to the power amplifier as inputs to the RNC algorithm in the power amplifier. Moreover, the vehicle RNC simulation system may receive speaker data representing a speaker signal from the power amplifier. The vehicle RNC simulation system includes a secondary path simulation model and a signal flow simulation model.
    Type: Grant
    Filed: October 15, 2021
    Date of Patent: May 16, 2023
    Assignee: Harman International Industries, Incorporated
    Inventors: Tingting Zhou, Yuliu Cao, Shiyu Chen
  • Patent number: 11635311
    Abstract: A system and method for multi-rate synchronization of a digital sensor that provides a digital sensor output signal and a processor arrangement that processes the digital sensor output signal according to a processing algorithm and that provides a processor output signal, including operating the digital sensor to provide the digital sensor output signal with a first sample rate, and operating the processor arrangement to provide a processor output signal with a second sample rate. The second sample rate is an integer multiple of the first sample rate.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: April 25, 2023
    Assignee: Harman Becker Automotive Systems GmbH
    Inventors: Yuliu Cao, Juergen Zollner, Franz Lorenz, Bin Gao, Shiyu Chen, Tingting Zhou, Alex Lee
  • Patent number: 11380297
    Abstract: A active noise cancellation (ANC) system may include an adaptive filter divergence detector for detecting divergence of the one or more controllable filters as they adapt, based on various temporal or frequency domain amplitude characteristics. Upon detection of a controllable filter divergence, the ANC system may be deactivated, or certain speakers may be muted. Alternatively, the ANC system may modify the diverged controllable filters to restore proper operation of the noise cancelling system. This may include adjusting a leakage value of an adaptive filter controller.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: July 5, 2022
    Assignee: HARMAN INTERNATIONAL INDUSTRIES, INCORPORATED
    Inventors: Kevin J. Bastyr, David Trumpy, Shiyu Chen
  • Publication number: 20220122577
    Abstract: A simulation test system and method for vehicle road noise cancellation (RNC) are provided in one or more embodiments of the present disclosure. The simulation test system may include a vehicle RNC simulation system and a power amplifier. The vehicle RNC simulation system is configured to simulate an RNC system in a vehicle environment. The power amplifier is configured to execute an RNC algorithm and may perform data communication with the vehicle RNC simulation system. The vehicle RNC simulation system transmits acceleration data representing an acceleration signal and microphone data representing a microphone signal to the power amplifier as inputs to the RNC algorithm in the power amplifier. Moreover, the vehicle RNC simulation system may receive speaker data representing a speaker signal from the power amplifier. The vehicle RNC simulation system includes a secondary path simulation model and a signal flow simulation model.
    Type: Application
    Filed: October 15, 2021
    Publication date: April 21, 2022
    Applicant: HARMAN INTERNATIONAL INDUSTRIES, INCORPORATED
    Inventors: Tingting ZHOU, Yuliu CAO, Shiyu CHEN
  • Publication number: 20210134259
    Abstract: A active noise cancellation (ANC) system may include an adaptive filter divergence detector for detecting divergence of the one or more controllable filters as they adapt, based on various temporal or frequency domain amplitude characteristics. Upon detection of a controllable filter divergence, the ANC system may be deactivated, or certain speakers may be muted. Alternatively, the ANC system may modify the diverged controllable filters to restore proper operation of the noise cancelling system. This may include adjusting a leakage value of an adaptive filter controller.
    Type: Application
    Filed: January 8, 2021
    Publication date: May 6, 2021
    Inventors: Kevin J. BASTYR, David TRUMPY, Shiyu CHEN
  • Patent number: 10891935
    Abstract: A active noise cancellation (ANC) system may include an adaptive filter divergence detector for detecting divergence of the one or more controllable filters as they adapt, based on various temporal or frequency domain amplitude characteristics. Upon detection of a controllable filter divergence, the ANC system may be deactivated, or certain speakers may be muted. Alternatively, the ANC system may modify the diverged controllable filters to restore proper operation of the noise cancelling system. This may include adjusting a leakage value of an adaptive filter controller.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: January 12, 2021
    Assignee: Harman International Industries, Incorporated
    Inventors: Kevin J. Bastyr, David Trumpy, Shiyu Chen
  • Publication number: 20200357377
    Abstract: A active noise cancellation (ANC) system may include an adaptive filter divergence detector for detecting divergence of the one or more controllable filters as they adapt, based on various temporal or frequency domain amplitude characteristics. Upon detection of a controllable filter divergence, the ANC system may be deactivated, or certain speakers may be muted. Alternatively, the ANC system may modify the diverged controllable filters to restore proper operation of the noise cancelling system. This may include adjusting a leakage value of an adaptive filter controller.
    Type: Application
    Filed: May 7, 2019
    Publication date: November 12, 2020
    Inventors: Kevin J. BASTYR, David TRUMPY, Shiyu CHEN
  • Patent number: 10513888
    Abstract: Techniques and systems to reduce deflection of a riser extending from an offshore platform. A device may include a main tube disposed along a length of the device. The device may also include a support member that may be coupled to the main tube, wherein the support member may surround the main tube. The device may include a buoyancy assembly that may at least partially surround the main tube, wherein the buoyancy assembly may have an elongated non-circular and non-cylindrical shape. The buoyancy assembly may also include buoyancy foam.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: December 24, 2019
    Assignee: Ensco International Incorporated
    Inventor: Shiyu Chen
  • Publication number: 20190360848
    Abstract: A system and method for multi-rate synchronization of a digital sensor that provides a digital sensor output signal and a processor arrangement that processes the digital sensor output signal according to a processing algorithm and that provides a processor output signal, including operating the digital sensor to provide the digital sensor output signal with a first sample rate, and operating the processor arrangement to provide a processor output signal with a second sample rate. The second sample rate is an integer multiple of the first sample rate.
    Type: Application
    Filed: May 23, 2019
    Publication date: November 28, 2019
    Applicant: Harman Becker Automoitve Systems GmbH
    Inventors: Yuliu Cao, Juergen Zollner, Franz Lorenz, Bin Gao, Shiyu Chen, Tingting Zhou, Alex Lee
  • Publication number: 20190085643
    Abstract: Techniques and systems to reduce deflection of a riser extending from an offshore platform. A device may include a main tube disposed along a length of the device. The device may also include a support member that may be coupled to the main tube, wherein the support member may surround the main tube. The device may include a buoyancy assembly that may at least partially surround the main tube, wherein the buoyancy assembly may have an elongated non-circular and non-cylindrical shape. The buoyancy assembly may also include buoyancy foam.
    Type: Application
    Filed: October 22, 2018
    Publication date: March 21, 2019
    Inventor: Shiyu Chen
  • Patent number: 10107048
    Abstract: Techniques and systems to reduce deflection of a riser extending from an offshore platform. A device may include a main tube disposed along a length of the device. The device may also include a support member that may be coupled to the main tube, wherein the support member may surround the main tube. The device may include a buoyancy assembly that may at least partially surround the main tube, wherein the buoyancy assembly may have an elongated non-circular and non-cylindrical shape. The buoyancy assembly may also include buoyancy foam.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: October 23, 2018
    Assignee: Ensco International Incorporated
    Inventor: Shiyu Chen
  • Publication number: 20180087329
    Abstract: Techniques and systems to reduce deflection of a riser extending from an offshore platform. A device may include a main tube disposed along a length of the device. The device may also include a support member that may be coupled to the main tube, wherein the support member may surround the main tube. The device may include a buoyancy assembly that may at least partially surround the main tube, wherein the buoyancy assembly may have an elongated non-circular and non-cylindrical shape. The buoyancy assembly may also include buoyancy foam.
    Type: Application
    Filed: September 26, 2017
    Publication date: March 29, 2018
    Inventor: Shiyu Chen