Abstract: A differential proportional temperature measurement circuit and method based on bidirectional constant voltage drive is proposed. The circuit and method applied to the precision temperature measurement of spacecraft, the main components include a bidirectional constant voltage source proportional bridge circuit, a differential and single-ended amplifier circuit, an analog-to-digital conversion circuit, a digital filter circuit, a data processing circuit and an isolated filter power supply circuit. The method adopts the bidirectional constant voltage drive technology, and enlarges and measures the difference between the voltage values of the reference resistor and the resistance to be measured by improving the sensing bridge of the ordinary commutation proportional method, and suppresses the long-term drift of the excitation unit and the voltage measurement unit. The method can meet the requirements of temperature measurement resolution of ?K magnitude and the power spectral density of ?K/Hz1/2 (0.