Abstract: Disclosed is a method for evaluating the fatigue damage and life of a bridge structure under a multi-factor coupling effect. The method comprises the following steps: S1, reproducing complex service environment action values; S2, analyzing performance values of a bridge structure; S3, calculating coupling fatigue damage of a vulnerable part; and S4, predicting a remaining life of the bridge structure. By adopting the method, the fatigue damage condition and remaining life of an in-service bridge under a multi-factor coupling effect can be accurately evaluated, and the effect of each factor/action and the coupling effect the factors/actions in fatigue damage of a vulnerable part are quantitatively analyzed, thereby providing data support and decision-making reference for the operation and maintenance management, reinforcement and repair, and optimal design of bridges.

Abstract: The invention relates to the field of biomedicine. In particular, the present invention relates to an interferon-based method for treating a disease, comprising intermittently administering an interferon-based therapeutic agent to a subject, where the disease is for example a viral infection or a cancer.

Abstract: The present invention relates to the field of biomedicine. Disclosed herein is interferon-based method and pharmaceutical combination for treating cancer. In particular, the present invention relates to an interferon-based method for treating cancer, comprising i) intermittently administering an interferon-based therapeutic agent, and ii) administering an additional anticancer agent, preferably, Gemcitabine, to a subject. The present invention also relates to a pharmaceutical combination for use in said method.

Abstract: Waveforms in power grids typically reveal a certain pattern with specific features and peculiarities driven by the system operating conditions, internal and external uncertainties, etc. This prompts an observation of different types of waveforms at the measurement points (substations). An innovative next-generation smart sensor technology includes a measurement unit embedded with sophisticated analytics for power grid online surveillance and situational awareness. The smart sensor brings additional levels of smartness into the existing phasor measurement units (PMUs) and intelligent electronic devices (IEDs). It unlocks the full potential of advanced signal processing and machine learning for online power grid monitoring in a distributed paradigm.

Abstract: An intelligent continuous polishing machine and an intelligent continuous polishing process therefor are provided. The intelligent continuous polishing machine includes a base platen, a rotary platen, a multi-beam bridge mechanism, two workpiece holding mechanisms, a lap measuring mechanism, a lap cutting mechanism, a small-conditioner holding mechanism, a large-conditioner holding mechanism, and a control computer. The intelligent continuous polishing process includes a normal polishing procedure, a lap surface shape measuring procedure, and three procedures for correcting the lap surface shape error: a lap cutting procedure, a sub-aperture correcting procedure, and a full-aperture correcting procedure. All of these procedures are controlled by the control computer through CNC programs.

Abstract: Waveforms in power grids typically reveal a certain pattern with specific features and peculiarities driven by the system operating conditions, internal and external uncertainties, etc. This prompts an observation of different types of waveforms at the measurement points (substations). An innovative next-generation smart sensor technology includes a measurement unit embedded with sophisticated analytics for power grid online surveillance and situational awareness. The smart sensor brings additional levels of smartness into the existing phasor measurement units (PMUs) and intelligent electronic devices (IEDs). It unlocks the full potential of advanced signal processing and machine learning for online power grid monitoring in a distributed paradigm.

Abstract: The present invention relates to granulocyte colony stimulating factor (G-CSF) modified with Y-shaped branched polyethylene glycol (YPEG-G-CSF) at a specific lysine (Lys 17) and the preparation thereof, as well as the pharmaceutical composition comprising YPEG-G-CSF and use thereof.

Abstract: The present invention relates to granulocyte colony stimulating factor (G-CSF) modified with Y-shaped branched polyethylene glycol (YPEG-G-CSF) at a specific lysine (Lys 17) and the preparation thereof, as well as the pharmaceutical composition comprising YPEG-G-CSF and use thereof.