Abstract: A method for shortening a duodenum of a subject, the method including: manipulating a first surface of the duodenum wall such that a first portion of the first surface of the duodenum wall is layered onto a second portion of the first surface of the duodenum wall, thereby creating at least one fold in the first surface of the duodenum wall, and securing, utilizing at least one implant, the position of the at least one fold in relation to a surrounding surface of the duodenum wall, thereby shortening the duodenum of the subject.

Abstract: An adhesive-applicator, and an implant that includes a wall formed from a porous fabric, are transcatheterally advanced to a heart of a subject. While a nozzle of the adhesive-applicator is disposed within an interior of the implant, the external surface of the wall is adhered to tissue of the heart by using the adhesive-applicator to apply an adhesive via the nozzle to the interior, such that a portion of the adhesive passes through the porous fabric of the wall to the external surface. Other embodiments are also described.

Abstract: A radiopaque frame is transluminally advanced to an atrium of a heart of a subject. The frame is expanded within a valve adjacent the atrium such that part of the frame remains disposed in the atrium. While the frame remains expanded within the valve, progressive portions of an annuloplasty structure are progressively positioned and anchored around the annulus using multiple anchors by, for each of the anchors sequentially (i) while fluoroscopically imaging the frame and a distal end of a delivery tool, and facilitated by mechanical guidance from the frame, positioning the distal end of the delivery tool between the frame and a wall of the atrium; and (ii) driving the anchor into the annulus laterally from the frame. Subsequently, the frame is contracted and withdrawn from the subject while leaving the annuloplasty structure anchored around the annulus. Other embodiments are also described.

Abstract: An implant comprises a first fabric and a second fabric. The first fabric comprises first fibers, disposed in a first orientation, and second fibers interwoven with the first fibers and disposed in a second orientation that is different to the first orientation. The second fabric comprises third fibers, and fourth fibers interwoven with the third fibers. The second fabric is attached to the first fabric in a manner in which: the first and second fabrics collectively form a body portion of the implant, the third fibers are disposed in a third orientation that is different to the first and second orientations, and the fourth fibers are disposed in a fourth orientation that is different to the first, second, and third orientations. The body portion is configured to be secured to an upstream surface of a native valve of a heart of a subject. Other embodiments are also described.