Patents by Inventor Shlomo Saidman, deceased

Shlomo Saidman, deceased has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof
    Patent number: 7074915
    Abstract: The invention relates to an antisense oligonucleotide targeted to the coding region of the human acetylcholinesterase (AChE), which selectively suppresses the AChE-R isoform of the enzyme. The antisense oligonucleotide is intended for use in the treatment and/or prevention of neuromuscular disorders, preferably myasthenia gravis. In addition, it can penetrate the blood-brain barrier (BBB) and destroy AChE-R within central nervous system neurons, while also serving as a carrier to transport molecules across the BBB.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: July 11, 2006
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Hermona Soreq, Jackiline Saidman, legal representative, Tama Evron, Shlomo Saidman, deceased