Patents by Inventor Shlomo Siedman

Shlomo Siedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and composition for enabling passage through the blood-brain-barrier
    Patent number: 6258780
    Abstract: A pharmaceutical composition for facilitating passage of compounds through the blood-brain barrier comprising the agent ACHE-I4 readthrough (SEQ ID No:1) splice variant or the I4 peptide (SEQ ID No:2) and analogues of each thereof and a pharmaceutically acceptable carrier is disclosed. Alternatively, the pharmaceutical composition for facilitating passage of compounds through the blood-brain barrier can comprise the agents adrenaline, atropine, dopamine and/or an adrenergic combination and a pharmaceutically acceptable carrier. The composition can comprise at least two of the agents. The composition of the present invention can optionally include the compound to be transported across the blood-brain barrier. Alternatively, the compound can be co-administered (simultaneously) with the composition or can be administered at some point during the biologically effective period of the action of the composition.
    Type: Grant
    Filed: November 20, 1997
    Date of Patent: July 10, 2001
    Assignee: Yissum Research Development Company
    Inventors: Hermona Soreq, Alon Friedman, Shlomo Siedman, Daniela Kaufer