Abstract: Biological filters for removing target components from biological fluids such as removal of pathogenic cells from whole blood, are described. The filters may include a medium comprising an inert surface, with capture material disposed on the inert surface. The filter may be configured to selectively recognize, capture, and remove target cells such as pathogenic cells associated with a disease, such as an autoimmune disease or cancer. Devices, systems, apparatuses, computer readable media, and methods associated with biological filtering are also provided.

Abstract: The invention provides robust, highly sensitive sensors for detecting and determining the presence and quantity of biologically important metal ions in a biological/physiological sample, by utilizing metal binding peptides immobilized on a surface.

Abstract: Provided are thermo-sensitive and light-sensitive polymer compositions including poly(4-vinyl pyridine) and poly(4-vinyl pyridine-co-butyl methacrylate).

Abstract: The present invention provides a novel photoelectrical device for efficient transmission of electrical signals to a neuron. This photoelectrical device comprises one or more charging units for coupling to and stimulating one or more neurons by charge, the charging unit comprising: a nanostructure-based electrode having a surface, which has a predetermined developed surface area for coupling to a neuron and which carries a plurality of photosensitive regions (e.g. quantum dots) interfacing with a biocompatible macromolecule for tuning the relative energy levels between the photosensitive regions and the electrode, as well as for directing the spatial polarity of charge separation the surface being thereby electrically chargeable and dischargeable in response to light excitation of the photosensitive regions, the charges stimulating the neuron when coupled to the surface.

Abstract: Provided are thermo-sensitive and light-sensitive polymer compositions including poly(4-vinyl pyridine) and poly(4-vinyl pyridine-co-butyl methacrylate).

Abstract: The present invention provides a novel photoelectrical device for efficient transmission of electrical signals to a neuron. This photoelectrical device comprises one or more charging units for coupling to and stimulating one or more neurons by charge, the charging unit comprising: a nanostructure-based electrode having a surface, which has a predetermined developed surface area for coupling to a neuron and which carries a plurality of photosensitive regions (e.g. quantum dots) interfacing with a biocompatible macromolecule for tuning the relative energy levels between the photosensitive regions and the electrode, as well as for directing the spatial polarity of charge separation the surface being thereby electrically chargeable and dischargeable in response to light excitation of the photosensitive regions, the charges stimulating the neuron when coupled to the surface.

Abstract: The present invention provides a surface-substrate for adherence of cells thereto. The surface-substrate comprises at least one micronail structure protruding from the surface, at least a region of the micronail having cellular-internalization promoting properties. The invention also provides an electronic device comprising a transistor structure, in which a gate electrode is formed with the at least one micronail protruding from the surface thereof.

Abstract: The present invention provides a surface-substrate for adherence of cells thereto. The surface-substrate comprises at least one micronail structure protruding from the surface, at least a region of the micronail having cellular-internalization promoting properties. The invention also provides an electronic device comprising a transistor structure, in which a gate electrode is formed with the at least one micronail protruding from the surface thereof.

Abstract: A device and method are presented for detecting analyte molecules in a medium. At least one FET (Field Effect Transistor) is provided being formed by at least one pair of source-drain electrodes and at least one gate electrode. The gate electrode is coated with a layer of receptor molecules that in the presence of said analytes catalyze a reaction that causes release of ions in a medium surrounding said receptor molecules. A monolayer of linker molecules is provided for linking said receptor molecules to said at least one gate such that a distance between the receptor molecules layer and the surface of the coated gate is smaller than 15A. In the prefered embodiments, the receptor molecules are enzymes (e.g. acetylcholine estarase) or peptides, and the analyte molecules are pesticides, herbicides and chemical pollutants of industrial origin.

Abstract: The present invention provides an organic composition comprising a water-soluble heteroaromatic compound, water and a polymer containing repeat units derived from six-membered aromatic heterocyclic monomers substituted in the 4-position relative to the heteroatom by an alkyl substituent, said six-membered aromatic heterocyclic monomer optionally being further substituted. The organic composition is excitable by predetermined incident electromagnetic radiation of predetermined intensity such that the excitation of a location of the composition by the predetermined incident radiation creates at least one of the following effects: a desired luminescence of the excited location and a desired electrical conductivity of the excited location.

Abstract: Organic superlattices formed by molecular layer epitaxy (MLE), and a novel MLE method of forming organic molecular monolayers are disclosed. The method utilized covalent linkage, combined with self-cleaning layer growth, to form pi-stacked, ordered, oriented monomolecular layers for use in a variety of electronic applications.

Abstract: Organic superlattices formed by molecular layer epitaxy (MLE), and a novel MLE method of forming organic molecular monolayers are disclosed. The method utilized covalent linkage, combined with self-cleaning layer growth, to form pi-stacked, ordered, oriented monomolecular layers for use in a variety of electronic applications.

Abstract: Organic superlattices fromed by molecular layer epitaxy (MLE), and a novel MLE method of forming organic molecular monolayers are disclosed. The method utilized covalent linkage, combined with self-cleaning layer growth, to form pi-stacked, ordered, oritented monomolecular layers for use in a variety of electronic applications.

Abstract: The present invention concerns an electrical junction between one transistor and at least one voltage sensitive cell such as a neuron. The invention further concerns transistors to be used in said junction and methods for their preparation. By another aspect the invention concerns “an artificial chemical synapse” i.e. a junction between a cell, which secretes an agent, and a transistor bearing receptors for the agent, wherein binding of the agent to the receptor changes an electrical property off the transistor.

Abstract: Organic superlattices fromed by molecular layer epitaxy (MLE), and a novel MLE method of forming organic molecular monolayers are disclosed. The method utilized covalent linkage, combined with self-cleaning layer growth, to form pi-stacked, ordered, oritented monomolecular layers for use in a variety of electronic applications.

Abstract: The present invention concerns an electrical junction between one transistor and at least one voltage sensitive cell such as a neuron. The invention further concerns transistors to be used in said junction and methods for their preparation. By another aspect the invention concerns “an artificial chemical synapse” i.e. a junction between a cell, which secretes an agent, and a transistor bearing receptors for the agent, wherein binding of the agent to the receptor changes an electrical property off the transistor.

Abstract: Organic superlattices formed by chemical vapor deposition/molecular layer epitaxy (CVD/MLE), and a novel CVD/MLE method of forming organic molecular monolayers are disclosed. The method utilized covalent linkage, combined with layer sublimation, to form p-stacked, ordered, oriented monomolecular layers for use in a variety of electronic applications.

Abstract: One manner of construction of robust, thin film materials with large second-order optical nonlinearities is the covalent self-assembly of aligned arrays of high-.beta. molecular chromophores into multilayer superlattices. the dispersion of the large second harmonic generation (SHG) response in a self-assembled (SA) film containing stilbazolium chromophore building blocks is disclosed, as well as the fabrication of SHG waveguides with such materials.

Abstract: A method of making a photochromic polysiloxane includes the steps of forming a photochromic spironaphthooxazine monomer including an alkene terminated side and, by addition reaction, covalently bonding the alkene carbon to [SiH] moieties of a siloxane polymer. Novel spironaphthooxazine monomers and photochromic polysiloxanes are disclosed.

Abstract: Method for the generation of second order nonlinear optical effects, including second harmonic generation, which comprises the steps of:i preparing a material in an xy planar film or xyz tridimensional form on a substrate and placing parallel electrodes on top of, inside, above or below said material, such that there is no protrusion of said electrodes into said material or a protrusion of at least one of said electrodes into said material is thinner than said material, wherein said material comprises at least one species of a hyperpolarizable component (a) and at least one species of a glass-forming organic material (b) providing a non-crystalline solid matrix in which molecules are not mobile, said components (a) and (b) being either distinct species or portions of a bifunctional molecule;ii subjecting said material of step (i) to an electric field essentially along the x-axis thereof; andiii directing a beam of light to impinge on and to be transmitted through said material treated as in step (ii), thus ge