Patents by Inventor Shmuel SHEN

Shmuel SHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF PRODUCING MOGROSIDES AND COMPOSITIONS COMPRISING SAME AND USES THEREOF
    Publication number: 20220170063
    Abstract: Isolated mogroside and mogrol biosynthetic pathway enzyme polypeptides useful in mogroside biosynthesis are provided. Mogroside biosynthetic pathway enzymes of the invention include squalene epoxidase (SE), epoxy hydratase (EH), cytochrome p450 (Cyp), cucurbitadienol synthase (CDS) and udp-glucosyl-transferase (UGT), Also provided are methods of producing a mogroside using the isolated mogroside and mogrol biosynthetic enzyme polypeptides, the methods comprising contacting a mogrol and/or a glycosylated mogrol (mogroside) with at least one UDP glucose glucosyl transferase (UGT) enzyme polypeptide of the invention catalyzing glucosylation of the mogrol and/or the glucosylated mogrol to produce a mogroside with an additional glucosyl moietie(s), thereby producing the mogroside.
    Type: Application
    Filed: December 28, 2021
    Publication date: June 2, 2022
    Applicant: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization
    Inventors: Maxim ITKIN, Rachel DAVIDOVICH-RIKANATI, Shahar COHEN, Vitaly PORTNOY, Adi DORON-FAIGENBOIM, Marina PETREIKOV, Shmuel SHEN, Yaakov TADMOR, Yosef BURGER, Efraim LEWINSOHN, Nurit KATZIR, Arthur A. SCHAFFER, Elad OREN
  • METHODS OF PRODUCING MOGROSIDES AND COMPOSITIONS COMPRISING SAME AND USES THEREOF
    Publication number: 20170283844
    Abstract: Isolated mogroside and mogrol biosynthetic pathway enzyme polypeptides useful in mogroside biosynthesis are provided. Mogroside biosynthetic pathway enzymes of the invention include squalene epoxidase (SE), expoxy hydratase (EH), cytochrome p450 (Cyp), cucurbitadienol synthase (CDS) and udp-glucosyl-transferase (UGT). Also provided are methods of producing a mogroside using the isolated mogroside and mogrol biosynthetic enzyme polypeptides, the methods comprising contacting a mogrol and/or a glycosylated mogrol (mogroside) with at least one UDP glucose glucosyl transferase (UGT) enzyme polypeptide of the invention catalyzing glucosylation of the mogrol and/or the glucosylated mogrol to produce a mogroside with an additional glucosyl moietie(s), thereby producing the mogroside.
    Type: Application
    Filed: September 10, 2015
    Publication date: October 5, 2017
    Inventors: Maxim ITKIN, Rachel DAVIDOVICH-RIKANATI, Shahar COHEN, Vitaly PORTNOY, Adi DORON-FAIGENBOIM, Marina PETREIKOV, Shmuel SHEN, Yaakov TADMOR, Yosef BURGER, Efraim LEWINSOHN, Nurit KATZIR, Arthur A. SCHAFFER, Elad OREN