Patents by Inventor Sho YOKOE

Sho YOKOE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250059577
    Abstract: Provided is a novel reverse transcriptase with excellent thermal stability. A reverse transcriptase comprising the following amino acid sequence: (a) an amino acid sequence having at least 75% identity with the amino acid sequence represented by SEQ ID NO: 2 or 3; or (b) an amino acid sequence having deletion, substitution, insertion, or addition of one or several amino acids in the amino acid sequence represented by SEQ ID NO: 2 or 3.
    Type: Application
    Filed: December 14, 2022
    Publication date: February 20, 2025
    Applicants: TOYOBO CO., LTD., SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION
    Inventors: Sho YOKOE, Kensuke OCHI, Shogo NAKANO, Sohei ITO
  • Publication number: 20220290112
    Abstract: An object is to provide a novel variant reverse transcriptase with excellent stability. The present invention provides a variant reverse transcriptase consisting of an amino acid sequence having at least 90% identity with an amino acid sequence represented by SEQ ID NO: 1, wherein a cysteine residue at a position corresponding to at least one position selected from the group consisting of 90, 157, 236, 262, 310, 409, 495, and 635 is modified. In a specific embodiment, the modification of the cysteine residue is substitution with at least one non-polar amino acid residue selected from the group consisting of alanine, glycine, valine, leucine, and isoleucine.
    Type: Application
    Filed: July 21, 2020
    Publication date: September 15, 2022
    Applicant: TOYOBO CO., LTD.
    Inventors: Takayoshi HIYAMA, Sho YOKOE