Patents by Inventor Shobha Varde

Shobha Varde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Characterizing Prostate Cancer
    Publication number: 20140315192
    Abstract: Methods and kits for predicting the course or aggressiveness of prostate cancer include detecting the methylation status of various genes.
    Type: Application
    Filed: March 6, 2013
    Publication date: October 23, 2014
    Applicant: Veridex, LLC
    Inventors: HAIYING WANG, SHOBHA VARDE, DONDAPATI CHOWDARY, JYOTI MEHROTRA, TATIANA VENER, ABHIJIT MAZUMDER
  • CHARACTERIZING PROSTATE CANCER
    Publication number: 20100003670
    Abstract: Methods and kits for predicting the course or aggressiveness of prostate cancer include detecting the methylation status of various genes.
    Type: Application
    Filed: October 30, 2007
    Publication date: January 7, 2010
    Inventors: Haiying Wang, Shobha Varde, Dondapati Chowdary, Jyoti Mehrotra, Tatiana Nener, Abhijit Mazumder
  • Detection of GSTP1 hypermethylation in prostate cancer
    Publication number: 20090186360
    Abstract: An assay for detecting prostate cancer includes reagents for detecting multiple methylation markers from within one gene such as GSTP1.
    Type: Application
    Filed: January 19, 2009
    Publication date: July 23, 2009
    Inventors: Abhijit Mazumder, Shobha A. Varde, Janet M. Vargo, Jonathan F. Baden
  • METHOD OF MODIFYING A MACROMOLECULE WITHOUT PRIOR EXTRACTION FROM A SAMPLE
    Publication number: 20090042290
    Abstract: The present invention encompasses a method of modifying a macromolecule without prior extraction from a sample by converting the macromolecule in the sample with a chemical, removing or converting chemical intermediates, if necessary; and purifying the resulting modified macromolecule.
    Type: Application
    Filed: August 6, 2007
    Publication date: February 12, 2009
    Inventors: Christopher Steele, Darin Oppenheimer, Sean Wuxiong Cao, Carrie A. Trust, George A. Green, IV, Jyoti Mehrotra, Tatiana I. Vener, Shobha A. Varde, Abhijit Mazumder
  • Methods of detecting methylation patterns within a CpG island
    Publication number: 20080213781
    Abstract: A method of increasing sensitivity of a DNA methylation assay by determining complementation within a CpG island of the methylated DNA.
    Type: Application
    Filed: February 15, 2008
    Publication date: September 4, 2008
    Inventors: Jonathan F. Baden, Jennifer Painter, Shobha A. Varde, Jyoti Mehrotra, Tatiana I. Vener, Abhijit Mazumder
  • Gene methylation assay controls
    Publication number: 20070122818
    Abstract: Methods, components, and kits for evaluating the effectiveness of methylation assays are presented as are methylation assays that include nucleotide sequence controls and methods of using them.
    Type: Application
    Filed: October 31, 2005
    Publication date: May 31, 2007
    Inventors: Abhijit Mazumder, Shobha Varde, Thomas Briggs
  • Detecting gene methylation
    Publication number: 20070059753
    Abstract: Methods, kits, and compositions for detecting the methylation status of various genes are useful in various diagnostic applications involving suspected proliferative disorders such as prostate cancer.
    Type: Application
    Filed: September 13, 2006
    Publication date: March 15, 2007
    Inventors: Tatiana Vener, Jyoti Mehrotra, Shobha Varde, Abhijit Mazumder, Jon Baden, John Backus
  • Oligonucleotides for multiplexed binding assays
    Publication number: 20060204971
    Abstract: An assay system for an analyte, the system having a solid support; and six or more pairs of oligonucleotides, each oligonucleotide of the pair being at least partially complementary to the other oligonucleotide of the pair. Each pair has a first oligonucleotide and a second oligonucleotide, the first oligonucleotide being immobilized to the solid support, and the second oligonucleotide having an analyte binding agent attached thereto. The oligonucleotides have a maximum of three consecutive identical nucleotides and less than about 10% cross-hybridization when used in assays conducted at from about 37° C. to about 45° C.
    Type: Application
    Filed: March 11, 2005
    Publication date: September 14, 2006
    Inventors: Shobha Varde, Mark Kunkel, Anton Yuryev