Abstract: The present inventors discovered novel multispecific antigen-binding molecules with excellent cellular cytotoxicity, which comprise a first domain comprising a first antigen variable region which binds to DLL3 and a second domain comprising a second antigen variable region which binds to T cell receptor complex. The present inventors prepared further bispecific antibodies, and assessed their T cell-dependent cell cytotoxicity (TDCC), and found that they also show strong TDCC activity. Since the molecules/antibodies of the present invention show a strong cytotoxicity against cells expressing DLL3, novel pharmaceutical compositions comprising the molecules/antibodies for treating or preventing various cancers associated with DLL3 can be provided.

Abstract: An actuator system that picks up workpieces aims to shorten tact time and to reduce damages to workpieces. The actuator system includes an actuator that picks up a workpiece, an external force detection sensor that detects a physical quantity that is correlated with an external force that is applied to the workpiece, a head unit that is connected to the actuator and the external force detection sensor without a communication network, the head unit being configured to control the actuator based on a sensing result from the external force detection sensor when a pickup request signal that is a signal requesting pickup of the workpiece is received, and a control device that is connected to the head unit over the communication network, the control device being configured to transmit the pickup request signal to the head unit.

Abstract: A vehicle seat including: a seat pad capable of elastically supporting an occupant, the seat pad having a seating portion that allows the occupant to seat on a front surface thereof, and the seating portion is divided in a seat width direction into a first region, a second region, and a central region formed between the first and the second region, the first region and the second region being capable of being concave-deformed toward a back surface of the seat pad opposite to the front surface when pressed by the occupant in a seating state, and in a free state where the seating portion is not pressed, a central region part in the central region arranged between the first and the second region that are to be concave-deformed has a shape concaved toward the back surface of the seat pad as compared to the first and the second region.

Abstract: A vehicle seat including: a seat pad capable of elastically supporting an occupant, the seat pad having a seating portion that allows the occupant to seat on a front surface thereof, and the seating portion is divided in a seat width direction into a first region, a second region, and a central region formed between the first and the second region, the first region and the second region being capable of being concave-deformed toward a back surface of the seat pad opposite to the front surface when pressed by the occupant in a seating state, and in a free state where the seating portion is not pressed, a central region part in the central region arranged between the first and the second region that are to be concave-deformed has a shape concaved toward the back surface of the seat pad as compared to the first and the second region.

Abstract: A vehicle seat includes a pair of left and right slide rails each having a lower rail extending in a front and rear direction of a vehicle and an upper rail slidably mounted to the lower rail. The lower rail is fixed to a floor F via brackets and so as to be spaced apart from the floor F. A reinforcing member extending in a left and right direction is disposed so as to span between rear end portions of the lower rails, and the reinforcing member is formed such that a bending strength about an axis in an up and down direction of a seat main body is lower than a bending strength about an axis in a front and rear direction of the seat main body.

Abstract: A vehicle seat includes a pair of left and right slide rails each having a lower rail extending in a front and rear direction of a vehicle and an upper rail slidably mounted to the lower rail. The lower rail is fixed to a floor F via brackets and so as to be spaced apart from the floor F. A reinforcing member extending in a left and right direction is disposed so as to span between rear end portions of the lower rails, and the reinforcing member is formed such that a bending strength about an axis in an up and down direction of a seat main body is lower than a bending strength about an axis in a front and rear direction of the seat main body.

Abstract: According to one embodiment, a simulation apparatus includes a hardware model execution unit that executes a hardware model, a software model execution unit that executes a software model, a simulation time management unit that sets a first simulation time indicating a total elapsed time of a simulation time of the hardware model, ahead by the simulation time of which the HW model notified, and sets the second simulation time indicating a total elapsed time of a simulation time of the software model, ahead by the simulation time of which the SW model notified, and a scheduler that compares the first simulation time with the second simulation time, causes the SW model or the HW model to be executed based on the comparison result, and causes only the hardware model to be executed instead of execution of an idle loop when the SW model awaits an interrupt from the HW model.

Abstract: A vehicle seat including: a tilting lever provided to an outer part of a seat main body, and by operating the tilting lever, a seat back can be tilted to a position of an upper surface of a seat cushion, wherein the tilting lever is arranged within an inwardly recessed space that is formed to a shield covering an outer part of the seat cushion, and an input movement of an operation to the tilting lever is completed within the recessed space.

Abstract: A virtualization program for being able to execute a simulation at high speed, allows a native code simulator to have a stack specific to each task that is managed by a multitask OS. Processes of creation, save, restoration and erasure of a context that a target CPU executes by means of a special control register operation is executed by an API provided by the native code simulator. When porting the multitask OS, the source code is altered so as to call the API. A stack specific to a task is assigned at the API and the stack is switched for switching the task to make context switching possible.

Abstract: A vehicle seat including: a tilting lever provided to an outer part of a seat main body, and by operating the tilting lever, a seat back can be tilted to a position of an upper surface of a seat cushion, wherein the tilting lever is arranged within an inwardly recessed space that is formed to a shield covering an outer part of the seat cushion, and an input movement of an operation to the tilting lever is completed within the recessed space.

Abstract: An object of the present invention is to provide a simulator for verifying plural products with common hardware configuration, in which peripheral hardware that can be reused are constituted by hardware and other peripheral hardware is constituted by software simulator, and simulation method. A simulator comprises: a hardware section that includes a peripheral hardware configuration with a structure required for a CPU and OS to operate alone; a software section that simulates the operation of peripheral hardware other than hardware constituting the hardware section as a peripheral hardware model; and an interface board that connects the hardware section and software section.

Abstract: According to one embodiment, a simulation apparatus includes a hardware model execution unit that executes a hardware model, a software model execution unit that executes a software model, a simulation time management unit that sets a first simulation time indicating a total elapsed time of a simulation time of the hardware model, ahead by the simulation time of which the HW model notified, and sets the second simulation time indicating a total elapsed time of a simulation time of the software model, ahead by the simulation time of which the SW model notified, and a scheduler that compares the first simulation time with the second simulation time, causes the SW model or the HW model to be executed based on the comparison result, and causes only the hardware model to be executed instead of execution of an idle loop when the SW model awaits an interrupt from the HW model.

Abstract: A virtualization program for being able to execute a simulation at high speed, allows a native code simulator to have a stack specific to each task that is managed by a multitask OS. Processes of creation, save, restoration and erasure of a context that a target CPU executes by means of a special control register operation is executed by an API provided by the native code simulator. When porting the multitask OS, the source code is altered so as to call the API. A stack specific to a task is assigned at the API and the stack is switched for switching the task to make context switching possible.

Abstract: An object of the present invention is to provide a simulator for verifying plural products with common hardware configuration, in which peripheral hardware that can be reused are constituted by hardware and other peripheral hardware is constituted by software simulator, and simulation method. A simulator comprises: a hardware section that includes a peripheral hardware configuration with a structure required for a CPU and OS to operate alone; a software section that simulates the operation of peripheral hardware other than hardware constituting the hardware section as a peripheral hardware model; and an interface board that connects the hardware section and software section.

Abstract: An object of the present invention is to provide a bridge program capable of achieving common use of the interface between a plurality of modules having different configurations and a hardware model obtained by modeling hardware with software. A bridge program allows a computer to execute: an acquisition step that acquires an operation instruction issued from the module to hardware model; a conversion step that converts the interface of the module into a common interface corresponding to the hardware model; and a discrimination step that acquires the operation instruction acquired by the acquisition step via the common interface into which the interface of the module is converted by the conversion step, discriminates to which hardware model the operation instruction is issued, and outputs the operation instruction to the discriminated hardware model.

Abstract: There is provided an interface board which synchronizes processings between a CPU board mounting a CPU and peripheral hardware models of peripheral hardware components modeled on a computer. The interface board connects a CPU board and a peripheral hardware simulator with each other. The CPU board has at least one CPU, and the peripheral hardware simulator simulates operation of at least one peripheral hardware component by a peripheral hardware model. The interface board includes: a wait instruction unit that receives an interruption notification from the CPU, then notifies the peripheral hardware model of the interruption notification, and sets the CPU into a wait state; and a release unit that releases the wait state in which the CPU has been set by the wait instruction unit, upon reception of an instruction to release the wait state from the peripheral hardware model which has been notified of the interruption notification.

Abstract: Herein disclosed is a backup system capable of easily performing backup and/or restore operations of an entire hard disk (HD) inclusive of a system region regardless of a type of an OS installed thereon in a computer such as a personal computer (PC). The backup system is suitable for backing up a hard disk of a computer which is connected to a server via a network, and characterized in that the server comprises: a boot OS creation section adapted to create a boot OS for the computer; a backup section adapted to store as a file the content of the hard disk in the computer into a designated backup destination; a management information database adapted to store therein management information of the computer; and a kernel image adapted to serve for the creation of the boot OS, as result of which it is possible to perform the backup and/or restore operations of the hard disk in the computer with easy manipulation by executing backup and restore functions from the boot OS.