Abstract: An energy management system is configured to calculate a percentage of satisfied based on the report data for each of the plurality of buildings; create, for each of the plurality of buildings, a plan for operating each of the air-conditioning facilities based on the percentage of satisfied and a predetermined target percentage of satisfied; calculate a first energy consumption amount based on the first piece of data; calculate a second energy consumption amount based on the second piece of data, the third piece of data, and the fourth piece of data, the second energy consumption amount being obtained when the each of the air-conditioning facilities is operated after a lapse of a predetermined time period; and control, when the first energy consumption amount is larger than the second energy consumption amount, the operation of the each of the air-conditioning facilities so as to achieve the second energy consumption amount.

Abstract: An anticancer agent for cancers in which an abundance of cyclin D1 protein is greater than that in a control, the anticancer agent including a compound represented by the following Formula (1) as an active ingredient (in Formula (1), R1 to R11 each independently represent a hydrogen atom, an aliphatic group having 1 to 30 carbon atoms, or a group represented by Formula RCO— (where, R represents an aliphatic group having 1 to 30 carbon atoms, or an aromatic group or heteroaromatic group having 1 to 10 carbon atoms)).

Abstract: An energy management system is configured to calculate a percentage of satisfied based on the report data for each of the plurality of buildings; create, for each of the plurality of buildings, a plan for operating each of the air-conditioning facilities based on the percentage of satisfied and a predetermined target percentage of satisfied; calculate a first energy consumption amount based on the first piece of data; calculate a second energy consumption amount based on the second piece of data, the third piece of data, and the fourth piece of data, the second energy consumption amount being obtained when the each of the air-conditioning facilities is operated after a lapse of a predetermined time period; and control, when the first energy consumption amount is larger than the second energy consumption amount, the operation of the each of the air-conditioning facilities so as to achieve the second energy consumption amount.

Abstract: An anticancer agent for cancers in which an abundance of cyclin D1 protein is greater than that in a control, the anticancer agent including a compound represented by the following Formula (1) as an active ingredient (in Formula (1), R1 to R11 each independently represent a hydrogen atom, an aliphatic group having 1 to 30 carbon atoms, or a group represented by Formula RCO— (where, R represents an aliphatic group having 1 to 30 carbon atoms, or an aromatic group or heteroaromatic group having 1 to 10 carbon atoms)).

Abstract: An energy management system has a prediction unit that determines an effective management pattern and predicts a DR demand amount and a reception unit that prepares a control plan and determines a DR response amount from a power consumption amount, and the reception unit prepares individual control plans for (1) minimizing the sum of power consumption amounts of a cooling tower and refrigerators without changing an amount of heat, (2) improving efficiency of the refrigerators by increasing a cold water temperature at an outlet of one refrigerator, (3) stopping an operation of one refrigerator, (4) reducing motive power of the pump and (5) operating an alternative facility and stopping the operation of one refrigerator, combines together the prepared individual control plans and prepares a control plan that satisfies the predicted DR demand amount.

Abstract: Eucaryotic cells like mammal and plant cells transfected with genes, called retrons, which code for stable single-stranded hybrid molecules (msDNA) containing RNA and DNA portions are disclosed. The retrons producing said linked RNA and DNA portions of the msDNAs also contain a gene encoding a reverse transcriptase (RT), which is necessary for the synthesis of the msDNAs. The msDNAs may contain foreign nucleic acid fragments which may be antisense fragments. These msDNA antisense vectors are useful for targeting genes of target proteins.

Abstract: A method for producing in vivo stable single-stranded DNAs in eucaryotic cells. The DNAs are multicopy single-stranded DNA (msDNA) structures constituted by a RNA and a DNA portion. The group of genes (retrons) producing said coupled RNA and DNA portions of the msDNAs and the gene encoding reverse transcriptase (RT). The transformed eucaryotes harboring these retrons. The new msDNAs which are encoded by the new retrons. The msDNAs can be used as vectors for antisense DNA and for amplification of inserted genes.