Patents by Inventor Shohei Yamamura
Shohei Yamamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240091771Abstract: An assay device and an assay method are each capable of ensuring the accuracy of a target substance detection section.Type: ApplicationFiled: September 17, 2021Publication date: March 21, 2024Inventors: Yusuke FUCHIWAKI, Masato TANAKA, Shohei YAMAMURA, Naoki MORISHITA, Kumiko KAMIYA, Seiichiro MATSUZAKI
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Publication number: 20220026424Abstract: In order to provide a specific solution for producing a microstructure equipped with a mechanism for selectively detecting a marker molecule expressed by a target cell, or a specific biomolecule, and for detecting and identifying a molecule to be detected using the microstructure, the present invention provides a nearly hemispherical shell-shaped structure made of a first conductive material, and an electrode layer made of a second conductive material disposed on the concave side of the nearly hemispherical shell-shaped structure, wherein the first conductive material includes a magnetic material and the second conductive material includes an electrode material, and the size (diameter) of the cavity surrounded by the electrode layer on the concave side of the nearly hemispherical shell-shaped structure is in the range of about 10 nm to about 50 ?m.Type: ApplicationFiled: February 26, 2020Publication date: January 27, 2022Inventors: Hyonchol KIM, Dai KATO, Naoshi KOJIMA, Shohei YAMAMURA, Tomoyuki KAMATA
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Patent number: 10584367Abstract: A cell-spreading device may include a microchamber chip having a microchamber capable of enclosing and retaining a cell, a channel-forming frame united with the microchamber chip to form a channel on the microchamber, an inlet provided in the channel-forming frame to allow a cell suspension to flow into the channel, and an outlet provided in the channel-forming frame to allow the cell suspension, which has been allowed to flow into the channel through the inlet, to flow out from the channel. When an aperture of the microchamber is projected perpendicularly to a longitudinal width of the microchamber chip, the void ratio that is a ratio of the sum total of voids to the longitudinal width is not more than 5%, the void being a length of a portion where the projected aperture of the microchamber is not present against the longitudinal width.Type: GrantFiled: July 1, 2013Date of Patent: March 10, 2020Assignee: KONICA MINOLTA, INC.Inventors: Jungo Araki, Kumiko Hoshi, Shohei Yamamura, Shouki Yatsushiro, Masatoshi Kataoka
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Patent number: 9249445Abstract: Disclosed is a detection method for detecting a specific cell in a sample containing multiple cells including the specific cell. Specifically disclosed is a detection method for detecting a specific cell in a sample containing multiple cells including the specific cell, which comprises the following steps (1) and (2): (1) retaining cells contained in the sample on a microarray chip which comprises multiple microchambers, wherein each of the microchambers can contain multiple cells; and (2) confirming the presence or absence of the specific cell in the cells retained on the microarray chip.Type: GrantFiled: September 2, 2009Date of Patent: February 2, 2016Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Shohei Yamamura, Shouki Yatsushiro, Masatoshi Kataoka
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Publication number: 20150337355Abstract: A cell-spreading device may include a microchamber chip having a microchamber capable of enclosing and retaining a cell, a channel-forming frame united with the microchamber chip to form a channel on the microchamber, an inlet provided in the channel-forming frame to allow a cell suspension to flow into the channel, and an outlet provided in the channel-forming frame to allow the cell suspension, which has been allowed to flow into the channel through the inlet, to flow out from the channel. When an aperture of the microchamber is projected perpendicularly to a longitudinal width of the microchamber chip, the void ratio that is a ratio of the sum total of voids to the longitudinal width is not more than 5%, the void being a length of a portion where the projected aperture of the microchamber is not present against the longitudinal width.Type: ApplicationFiled: July 1, 2013Publication date: November 26, 2015Inventors: Jungo ARAKI, Kumiko HOSHI, Shohei YAMAMURA, Shouki YATSUSHIRO, Masatoshi KATAOKA
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Publication number: 20150203804Abstract: Provided is a micro chamber chip for cell expansion, with which the non-specific adsorption of cells onto a surface other than a micro chamber can be suppressed, and a rare cell from a substance that contains a large quantity of cells, such as a blood, can be stored, held and observed without a leakage of the rare cell. A micro chamber chip for cell expansion is provided with a micro chamber chip in which a micro chamber configured to store and hold one or more cells is formed on an upper surface of a substrate, wherein an upper surface of the micro chamber chip and an inner wall surface of the micro chamber are coated with a blocking agent that can suppress a non-specific adsorption of a cell on the upper surface.Type: ApplicationFiled: July 1, 2013Publication date: July 23, 2015Inventors: Kumiko Hoshi, Jungo Araki, Shohei Yamamura, Shouki Yatsushiro, Masatoshi Kataoka
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Patent number: 9017969Abstract: The present invention provides: genetically modified yeasts such as mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and a decreased ability to produce O-linked sugar chains, mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and further having an ability to produce N-linked sugar chains of GlcNAc1Man5GlcNAc2, and mutant yeasts having an increased ability to produce and secrete proteins and an ability to produce N-linked sugar chains of Man5GlcNAc2; and a method for producing glycoproteins using them.Type: GrantFiled: March 1, 2012Date of Patent: April 28, 2015Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Hiroko Abe, Kazuya Tomimoto, Yasuko Fujita, Tomoko Iwaki, Yasunori Chiba, Yoshihiro Nakajima, Kenichi Nakayama, Masatoshi Kataoka, Shouki Yatsushiro, Shohei Yamamura
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Patent number: 8664003Abstract: A chip useful for treating cells and the like which has a mechanism and a structure wherein the size of a hole pattern is arbitrarily changed so that cells can easily move in and get out from the hole in scattering or collecting cells but can hardly get out from the hole during washing or antigen-stimulation. The chip comprises a crosslinked product of a temperature-responsive polymer as a constituting member and being provided with a film having a hole pattern on the surface of a baseboard. A method of producing the chip comprises applying a composition containing a crosslinkable temperature-responsive polymer on the surface of a baseboard to thereby form a coating film, crosslinking the coating film to thereby form the crosslinked product as described above and then forming a hole pattern on the coating film of the crosslinked product.Type: GrantFiled: August 8, 2012Date of Patent: March 4, 2014Assignees: Toyama Prefecture, Nissan Chemical Industries, Ltd.Inventors: Eiichi Tamiya, Yoshiyuki Yokoyama, Satoshi Fujiki, Katsumi Tanino, Atsushi Muraguchi, Hiroyuki Kishi, Yoshiharu Tokimitsu, Shohei Yamamura
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Publication number: 20130171692Abstract: The present invention provides: genetically modified yeasts such as mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and a decreased ability to produce O-linked sugar chains, mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and further having an ability to produce N-linked sugar chains of GlcNAc1Man5GlcNAc2, and mutant yeasts having an increased ability to produce and secrete proteins and an ability to produce N-linked sugar chains of Man5GlcNAc2; and a method for producing glycoproteins using them.Type: ApplicationFiled: March 1, 2012Publication date: July 4, 2013Applicant: National Institute of Advanced Industrial Science and TechnologyInventors: Hiroke Abe, Kazuya Tomimoto, Yasuko Fujita, Tomoko Iwaki, Yasunori Chiba, Yoshihiro Nakajima, Kenichi Nakayama, Masatoshi Kataoka, Shouki Yatsushiro, Shohei Yamamura
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Publication number: 20120301942Abstract: A chip useful for treating cells and the like which has a mechanism and a structure wherein the size of a hole pattern is arbitrarily changed so that cells can easily move in and get out from the hole in scattering or collecting cells but can hardly get out from the hole during washing or antigen-stimulation. The chip comprises a crosslinked product of a temperature-responsive polymer as a constituting member and being provided with a film having a hole pattern on the surface of a baseboard. A method of producing the chip comprises applying a composition containing a crosslinkable temperature-responsive polymer on the surface of a baseboard to thereby form a coating film, crosslinking the coating film to thereby form the crosslinked product as described above and then forming a hole pattern on the coating film of the crosslinked product.Type: ApplicationFiled: August 8, 2012Publication date: November 29, 2012Applicants: TOYAMA PREFECTURE, NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Eiichi TAMIYA, Yoshiyuki YOKOYAMA, Satoshi FUJIKI, Katsumi TANINO, Atsushi MURAGUCHI, Hiroyuki KISHI, Yoshiharu TOKIMITSU, Shohei YAMAMURA
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Publication number: 20110189723Abstract: Disclosed is a detection method for detecting a specific cell in a sample containing multiple cells including the specific cell. Specifically disclosed is a detection method for detecting a specific cell in a sample containing multiple cells including the specific cell, which comprises the following steps (1) and (2): (1) retaining cells contained in the sample on a microarray chip which comprises multiple microchambers, wherein each of the microchambers can contain multiple cells; and (2) confirming the presence or absence of the specific cell in the cells retained on the microarray chip.Type: ApplicationFiled: September 2, 2009Publication date: August 4, 2011Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Shohei Yamamura, Shouki Yatsushiro, Masatoshi Kataoka
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Publication number: 20090130384Abstract: [Problems] To provide a novel chip useful for treating cells and the like which has a mechanism and a structure wherein the size of a hole pattern is arbitrarily changed so that cells can easily move in and get out from the hole in scattering or collecting cells but can hardly get out from the hole during washing or antigen-stimulation. [Means for Solving Problems] A chip comprising a crosslinked product of a temperature-responsive polymer as a constituting member and being provided with a film having a hole pattern on the surface of a baseboard. A method of producing a chip which comprises a crosslinked product of a temperature-responsive polymer as a constituting member and is provided with a film having a hole pattern on the surface of the baseboard.Type: ApplicationFiled: September 27, 2006Publication date: May 21, 2009Applicants: TOYAMA PREFECTURE, NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Eiichi Tamiya, Yoshiyuki Yokoyama, Satoshi Fujiki, Katsumi Tanino, Atsushi Muraguchi, Horoyuki Kishi, Yoshiharu Tokimitsu, Shohei Yamamura