Patents by Inventor Shohgo Atarashi
Shohgo Atarashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5508428Abstract: A compound of formula I, having antibacterial activity and a pharmaceutical composition containing the compound of formula I: ##STR1## wherein Q represents a partial structure of formula II: ##STR2## wherein all substituents are defined in the specification.Type: GrantFiled: April 12, 1995Date of Patent: April 16, 1996Assignee: Daiichi Phamaceutical Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi, Masazumi Imamura, Youichi Kimura
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Patent number: 5476950Abstract: This invention provides novel pyridonecarboxylic acid derivatives having a quite high antimicrobial activity. The derivatives have the following formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 represent each a hydrogen or C.sub.1-C.sub.6 alkyl group; R.sup.4 represents an ethyl, 2-fluoroethyl, vinyl, isopropyl, isopropenyl or cyclopropyl group; and X represents CH, C--F, C--Cl or Ncharacterized in that R.sup.2 and R.sup.3 are not hydrogen at the same time.Type: GrantFiled: March 20, 1995Date of Patent: December 19, 1995Assignee: Daiichi Seiyaku Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi
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Patent number: 5463053Abstract: An optically active pyridobenzoxazine derivative represented by formula (I): ##STR1## wherein R.sup.1 and R.sup.2 wherein R.sup.1 and R.sup.2, which may be the same or different, each represent an alkyl group having from 1 to 6 carbon atoms, a halogenated alkyl group having from 1 to 6 carbon atoms, a hydroxyalkyl group having from 1 to 6 carbon atoms, or an alkoxymethyl group having from 2 to 7 carbon atoms; R.sup.3 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms, an acyl group having from 2 to 7 carbon atoms, a halogen-substituted or unsubstituted alkyloxycarbonyl group having from 2 to 7 carbon atoms, a phenylmethyloxycarbonyl group, or a phenylmethyloxycarbonyl group whose phenyl moiety is substituted with a halogen atom, a nitro group, or a methoxy group; R.sup.4 represents a methyl or fluoromethyl group which is in a .beta.-configuration; R.sup.Type: GrantFiled: January 21, 1994Date of Patent: October 31, 1995Assignee: Daiichi Pharmaceutical Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi, Yoichi Kimura, Katsuhiro Kawakami
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Patent number: 5416222Abstract: This invention provides novel pyridonecarboxylic acid derivatives having a quite high antimicrobial activity. The derivatives have the following formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 represent each a hydrogen or C.sub.1 -C.sub.6 alkyl group; R.sup.4 represents an ethyl, 2-fluoroethyl, vinyl, isopropyl, isopropenyl or cyclopropyl group; and X represents CH, C--F, C--Cl or N characterized in that R.sup.2 and R.sup.3 are not hydrogen at the same time.Type: GrantFiled: December 24, 1991Date of Patent: May 16, 1995Assignee: Daiichi Seiyaku Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi
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Patent number: 5380874Abstract: This invention provides novel pyridonecarboxylic acid derivatives having a quite high antimicrobial activity. The derivatives have the following formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 represent each a hydrogen or C.sub.1 -C.sub.6 alkyl group; R.sup.4 represents an ethyl, 2-fluoroethyl, vinyl, isopropyl, isopropenyl or cyclopropyl group; and X represents CH, C--F, C--Cl or N characterized in that R.sup.2 and R.sup.3 are not hydrogen at the same time.Type: GrantFiled: March 4, 1994Date of Patent: January 10, 1995Assignee: Daiichi Seiyaku Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi
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Patent number: 5286723Abstract: The present invention relates to spiro compounds of general formula I: ##STR1## wherein the substituents are herein below defined. The present invention relates to antibacterial spiro compounds which are of value as drugs for humans, veterinary drugs or drugs for use in fish culture or as preservatives, and to antibacterial compositions containing one or more of the same compounds as active ingredients.Type: GrantFiled: June 22, 1992Date of Patent: February 15, 1994Assignee: Daiichi Seiyaku Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi, Masazumi Imamura, Youichi Kimura
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Patent number: 5142046Abstract: An optically action pyridobenzoxazine derivative, a process for preparing the same and a novel intermediate useful for preparing the optically active pyridobenzoxazine derivative are disclosed. The optically active pyridobenzoxazine derivative possesses increased antimicrobial activity and reduced toxicity. The intermediate is useful for preparing such optically active pyridobenzoxazine derivatives such as Ofloxacin and anolog compounds.Type: GrantFiled: August 28, 1991Date of Patent: August 25, 1992Assignee: Daiichi Pharmaceutical Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi, Masazumi Imamura, Shuichi Yokohama, Nobuyuki Higashihashi, Katsuichi Sakano, Masayuki Ohshima
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Patent number: 5098912Abstract: This invention provides novel pyridonecarboxylic acid derivatives having a quite high antimicrobial activity. The derivatives have the following formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 represent each a hydrogen or C.sub.1 -C.sub.6 alkyl group; R.sup.4 represents an ethyl, 2-fluoroethyl, vinyl, isopropyl, isopropenyl or cyclopropyl group; and X represents CH, C-F, C-Cl or N wherein (i) one of R.sup.1, R.sup.2 and R.sup.3 represents a hydrogen or C.sub.1 -C.sub.6 alkyl group, and (ii) either R.sup.1 forms a methylene chain having 2 to 4 carbon atoms together with R.sup.2 or R.sup.3, or R.sup.2 and R.sup.3 form together an alkylene chain having 2 to 5 atoms and R.sup.4 represents an ethyl, 2-fluorethyl, vinyl, isopropyl, isopropenyl or cyclopropyl group and X represents CH, C-F, or C-Cl and salt thereof.Type: GrantFiled: December 12, 1989Date of Patent: March 24, 1992Assignee: Daiichi Seiyaku Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi
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Patent number: 5053407Abstract: An optically action pyridobenzoxazine derivative, a process for preparing the same and a novel intermediate useful for preparing the optically active pyridobenzoxazine derivative are disclosed. The optically active pyridobenzoxazine derivative possesses increased antimicrobial activity and reduced toxicity. The intermediate is useful for preparing such optically active pyridobenzoxazine derivatives such as Ofloxacin and anolog compounds.Type: GrantFiled: June 20, 1986Date of Patent: October 1, 1991Assignee: Daiichi Pharmaceutical Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi, Masazumi Imamura, Shuichi Yokohama, Nobuyuki Higashihashi, Katsuichi Sakano, Masayuki Ohshima
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Patent number: 4985557Abstract: An optically action pyridobenzoxazine derivative, a process for preparing the same and a novel intermediate useful for preparing the optically active pyridobenzoxazine derivative are disclosed. The optically active pyridobenzoxazine derivative possesses increased antimicrobial activity and reduced toxicity. The intermediate is useful for preparing such optically active pyridobenzoxazine derivatives such as Ofloxacin and anolog compounds.Type: GrantFiled: March 23, 1989Date of Patent: January 15, 1991Assignee: Daiichi Seiyaku Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi, Masazumi Imamura, Shuichi Yokohama, Nobuyuki Higashihashi, Katsuichi Sakano, Masayuki Ohshima
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Patent number: 4895944Abstract: An optically active 3,4-dihydrobenzoxazine derivative, a process for preparing the same and an intermediate of 2H-benzoxazine useful for synthesizing the above mentioned optically active 3,4-dihydrobenzoxazine are disclosed.Type: GrantFiled: December 28, 1987Date of Patent: January 23, 1990Assignee: Daiichi Seiyaku Company, Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi
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Patent number: 4871852Abstract: Novel 4-oxoguinoline-3-carboxylic acid derivatives having the formula ##STR1## wherein X.sup.1 represents a halogen or hydrogen atom, X.sup.2 represents a halogen or hydrogen atom, X.sup.3 represents a halogen atom, and R.sup.1, R.sup.2 and R.sup.3 each represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, and physiologically acceptable salts thereof, are disclosed. These compounds have excellent antibacterial activity against gram-positive and gram-negative bacteria and beneficial pharmacokinetic properties.Type: GrantFiled: November 27, 1987Date of Patent: October 3, 1989Assignee: Daiichi Seiyaku Co., Ltd.Inventors: Isao Hayakawa, Shohgo Atarashi, Shuichi Yokohama, Masazumi Imamura