Abstract: To provide a contact probe which can easily be connected with a measurement apparatus electrically, can measure a high speed and high frequency signal with a fine pitch easily and correctly, and can easily cope with signal measurement for a plurality of channels, and a method of making the contact probe. It includes a first printed wiring board 3 having a signal electrode 10a and a ground electrode 10b used as a contact part with respect to a measuring object, in which the signal electrode 10a and ground electrode 10b are formed of a metal wiring pattern on a substrate, and a second printed wiring board 2 with a coaxial line structure having shield electrodes 12, 17, 18 which enclose a signal line 15a and the surroundings of the signal line 15a through an insulating layer.

Abstract: An injection molding system has a plurality of movable sub-clamping units each having a mold therein and a main clamping unit for clamping the mold in the sub-clamping unit. Each of the sub-clamping units alternately enters the main clamping unit for only a filling process to receive the melted resin material from an injection unit. Each sub-clamping unit clamps the mold by its own clamping mechanism and moves to the main clamping unit where the mold is further clamped by a higher clamping pressure by the main clamping unit during the filling process. Each sub-clamping unit is retracted from the main clamping unit immediately after the filling process and stayed outside of the main clamping unit through the holding process and the cooling process, thereby dramatically improving the molding production efficiency.

Abstract: An injection molding system has a plurality of movable sub-clamping units each having a mold therein and a main clamping unit for clamping the mold in the sub-clamping unit. Each of the sub-clamping units alternately enters the main clamping unit for only an filling process to receive the melted resin material from an injection unit. Each sub-clamping unit clamps the mold by its own clamping mechanism and moves to the main clamping unit where the mold is further clamped by a higher clamping pressure by the main clamping unit during the filling process. Each sub-clamping unit is retracted from the main clamping unit immediately after the filling process and stayed outside of the main clamping unit through the holding process and the cooling process, thereby dramatically improving the molding production efficiency.

Abstract: Pharmaceutical compositions containing an isoquinoline derivative exhibit an excellent inhibitory action to an isozyme of phosphodiesterase of the type IV (PDEIV). The active component of the pharmaceutical composition is an isoquinoline derivative which is represented by the general formula: ##STR1## wherein R is an ethoxy group, or which is a pharmaceutically-acceptable salt of a compound represented by said formula. The isoquinoline derivatives have an excellent inhibitory action which is highly specific to PDEIV. They are highly useful as pharmaceuticals such as antidepressive agents, tranquilizers, antidemential agents, antiinflammatory agents, antiallergic agents, antiasthmatic agents, liver-protecting agents, and diuretic agents.

Abstract: The present invention relates to a N.sup.6,N.sup.6 -disubstituted-cyclic adenosine-3',5'-monophosphate represented by the formula ##STR1## wherein R represents a linear alkyl group having 3 or more carbon atoms or a branched alkyl group having 4 or more carbon atoms, an aralkyl group or an alkenyl group; A.sup..sym. represents a hydrogen ion, an alkali metal ion, an alkaline earth metal ion, an ammonium ion or an organoammonium ion, or a salt thereof, and a cardiac composition comprising it as an effective component, and further includes a process for preparing a compound represented by the formula ##STR2## wherein R.sub.1 represents an alkyl group, an aralkyl group or an alkenyl group and A.sup..sym. has the same meanings as defined above, or a salt thereof, characterized in that a 2'-O-protected-cyclic adenosine-3',5'-monophosphate represented by the formula ##STR3## wherein Y represents a protecting group and A.sup..sym.

Abstract: An .alpha.-alumina-based ceramics material comprising crystals of a particle diameter of no greater than 0.2 .mu.m on an average or a particle diameter of substantially no greater than 0.2 .mu.m, and having a density of no lower than 95% of the theoretical density and a hardness of no lower than 2,000 kg/mm.sup.2, and a method for the production thereof.

Abstract: A composition for use in the treatment of heart failure of mammals which comprises, as its active ingredient, an N.sup.6 -substututed-adenosine-3',5'-cyclic phosphate represented by the following general formula (I) or a physiologically acceptable salt thereof: ##STR1## wherein R represents alkyl or aralkyl group and a pharmaceutically acceptable carrier, as well as a method for treating heart failure of mammals which comprises administering said composition.