Abstract: The present invention addresses the problem of providing a fundamental therapeutic method for renal diseases including glomerulonephritis such as IgA nephropathy. To solve this problem, the present invention pertains to an agent for increasing CD25-positive regulatory T cells in kidney, said agent comprising mesenchymal stem cells. The regulatory T cell-increasing agent of the present invention exerts a sufficient therapeutic effect even if further containing a cryopreservation liquid at a concentration of less than 5% (v/v).

Abstract: An agent for inhibiting the action of a target RNA based on RNA interference and ASO with a passenger strand and a guide strand for a target RNA, wherein both ends of double-stranded RNA formed pairing of the passenger strand and the guide strand are blunt ends, and one or two or more selected from the group consisting of the units represented by formula (1) and formula (2) below at the following positions (a) and (b): (a) 5? end side and 3? end side of the passenger strand, (b) 3? end side of the guide strand (in which X represents an oxygen atom or sulfur atom), (in which X represents an oxygen atom or sulfur atom).

Abstract: A highly reliable rotating electric machine is provided in which the amount of charge discharged by partial discharge can be reduced while the machine is downsized by decreasing the thickness of insulation for coils, and it is possible to prevent paper flapping in coil end portions because of rotating wind produced by rotation of the rotor.

Abstract: An object of the present invention is to provide a method capable of detecting whether a subject has systemic lupus erythematosus (preferably nephrotic syndrome) with high accuracy without performing a renal biopsy, a biomarker for carrying out such detection, and the like. The concentration of 3?,4?-didehydro-3?-deoxycytidine in urine collected from a test subject is measured, and this concentration is compared with a reference concentration for control, which allows to detect whether the above-mentioned test subject has systemic lupus erythematosus (preferably lupus nephritis) with high accuracy.

Abstract: A highly reliable rotating electric machine is provided in which the amount of charge discharged by partial discharge can be reduced while the machine is downsized by decreasing the thickness of insulation for coils, and it is possible to prevent paper flapping in coil end portions because of rotating wind produced by rotation of the rotor.

Abstract: The rotating electrical machine of the present invention includes a stator coil obtained by curing the impregnating resin injected into the whole stator coil unit after an electrically insulated coil unit with a mica tape having been wrapped around a conductor is slotted into stator iron core slots via a slot liner. The high-heat-resistance resin component of the slot liner contains at least an epoxy resin having 3 or more epoxy groups. The high-heat-resistance resin component of the mica tape contains at least an alicyclic epoxy resin. The impregnating resin contains a bifunctional epoxy resin, and an acid curing agent having one acid anhydride skeleton. With the impregnating resin, the high-heat-resistance resin components of the slot liner and the mica tape form a liner cured portion and a mica insulating layer portion as an integral unit of different resin compositions inside the slot.

Abstract: The rotating electrical machine of the present invention includes a stator coil obtained by curing the impregnating resin injected into the whole stator coil unit after an electrically insulated coil unit with a mica tape having been wrapped around a conductor is slotted into stator iron core slots via a slot liner. The high-heat-resistance resin component of the slot liner contains at least an epoxy resin having 3 or more epoxy groups. The high-heat-resistance resin component of the mica tape contains at least an alicyclic epoxy resin. The impregnating resin contains a bifunctional epoxy resin, and an acid curing agent having one acid anhydride skeleton. With the impregnating resin, the high-heat-resistance resin components of the slot liner and the mica tape form a liner cured portion and a mica insulating layer portion as an integral unit of different resin compositions inside the slot.

Abstract: A dry mica tape includes a base material, a binder resin layer A formed on the base material and including an epoxy resin and an accelerator, a mica paper layer formed in contact with the binder resin layer A, and a binder resin layer B formed in contact with the mica paper layer, including an epoxy resin, and providing a cured resin with a higher glass transition point than that of a cured resin of an impregnating varnish only by reacting with an impregnating varnish including an epoxy resin impregnated into the dry mica tape wound around a conductor.

Abstract: To provide an immunosuppressing agent having high therapeutic effect and uses thereof. The immunosuppressing agent includes adipose-derived mesenchymal stem cells obtained by low-serum culture.

Abstract: A dry mica tape includes a base material, a binder resin layer A formed on the base material and including an epoxy resin and an accelerator, a mica paper layer formed in contact with the binder resin layer A, and a binder resin layer B formed in contact with the mica paper layer, including an epoxy resin, and providing a cured resin with a higher glass transition point than that of a cured resin of an impregnating varnish only by reacting with an impregnating varnish including an epoxy resin impregnated into the dry mica tape wound around a conductor.

Abstract: Titanium resistant to discoloration in an atmospheric environment characterized by having an average carbon concentration of 14 at % or less in a range to a depth of 100 nm from the surface and having an oxide film of a thickness of 12 to 40 nm at its surface. Titanium resistant to discoloration in an atmospheric environment characterized in that, in X-ray diffraction of its surface, a ratio (X1/X2) of a (200) peak intensity X1 of TiC to a (110) peak intensity X2 of titanium is not more than 0.18 and by having an oxide film of a thickness of 12 to 40 nm at its surface.

Abstract: Titanium resistant to discoloration in an atmospheric environment characterized by having an average carbon concentration of 14 at % or less in a range to a depth of 100 nm from the surface and having an oxide film of a thickness of 12 to 40 nm at its surface. Titanium resistant to discoloration in an atmospheric environment characterized in that, in X-ray diffraction of its surface, a ratio (X1/X2) of a (200) peak intensity X1 of TiC to a (110) peak intensity X2 of titanium is not more than 0.18 and by having an oxide film of a thickness of 12 to 40 nm at its surface.

Abstract: A highly thermal-conductive and thermal-resistant electrically insulated coil with less outflow of a thermosetting resin composition can be produced, to provide a small-scale, light-weight rotating machine with high power. The thermosetting resin composition comprises (a) a polyfunctional epoxy resin containing three or more p-(2,3-epoxypropoxy) phenyl groups and a group represented by the Chemical formula 1; or an epoxy resin with a naphthalene backbone, represented by the Chemical formula 3, 4 or 5 or an epoxy resin with an anthracene backbone, such as diglycidyl ether of anthracene diol and triglycidyl ether of anthracene triol; (b) a bifunctional epoxy resin containing two p-(2,3-epoxypropoxy) phenyl groups; (c) an acid anhydride curing agent; and (d) a metal acetonate curing catalyst represented by the Chemical formula 2 at 0.1 to 5 parts by weight per 100 parts by weight of the epoxy resins.