Patents by Inventor Shoichiro Ohta

Shoichiro Ohta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for diagnosing chronic sinusitis
    Patent number: 9625451
    Abstract: The present invention provides a method for detecting chronic sinusitis, which comprises measuring the concentration of a periostin protein in blood or nasal secretion collected from a test subject. Thereby, a method for detecting chronic sinusitis, which is capable of detecting chronic sinusitis more simply, more promptly and less invasively, is provided.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: April 18, 2017
    Assignees: SAGA UNIVERSITY, YAMAGATA UNIVERSITY
    Inventors: Kenji Izuhara, Shoichiro Ohta, Kazuhiko Arima, Hiroshi Shiraishi, Shoichi Suzuki, Nobuo Ohta, Akihiro Ishida, Yusuke Suzuki
  • Method for screening for a therapeutic agent for idiopathic interstitial pneumonia
    Patent number: 9482676
    Abstract: The present invention provides a method for detecting idiopathic interstitial pneumonia, which comprises measuring the expression level of a periostin gene or the amount of a periostin protein in a biological sample. Thereby, a method for detecting idiopathic interstitial pneumonia using a marker is provided.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: November 1, 2016
    Assignees: SAGA UNIVERSITY, KURUME UNIVERSITY
    Inventors: Kenji Izuhara, Shoichiro Ohta, Hiroshi Shiraishi, Hisamichi Aizawa, Tomoaki Hoshino, Masaki Okamoto
  • ANTIBODY CAPABLE OF BINDING TO SPECIFIC REGION OF PERIOSTIN, AND METHOD FOR MEASURING PERIOSTIN USING SAME
    Publication number: 20160313351
    Abstract: The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin.
    Type: Application
    Filed: April 29, 2016
    Publication date: October 27, 2016
    Applicants: SHINO-TEST CORPORATION, SAGA UNIVERSITY, KURUME UNIVERSITY
    Inventors: Kenji IZUHARA, Shoichiro OHTA, Tomoaki HOSHINO, Yoshinori AZUMA, Junya ONO
  • Drug for Disease Caused by Expression of Periostin Except Eye Disease, and Use Thereof
    Publication number: 20160304866
    Abstract: The present invention is intended to provide a novel molecule that inhibits the expression of the periostin gene that is effective in treatment of diseases caused by the expression of periostin except for eye diseases. A drug for a disease caused by the expression of periostin except for an eye disease includes, as an expression inhibitory sequence for the periostin gene, a nucleic acid molecule including a nucleotide that has a base sequence represented by any one of SEQ ID NOs: 1 to 19. The drug for disease according to the present invention can inhibit the expression of the periostin gene. Thus, it can be used for treatment of diseases (except for eye diseases) caused by the expression of the periostin gene, specifically skin diseases, respiratory diseases, gastrointestinal diseases, and the like.
    Type: Application
    Filed: September 26, 2014
    Publication date: October 20, 2016
    Applicant: AQUA Therapeutics Co., Ltd.
    Inventors: Kenji Izuhara, Kazuhiko Arima, Shoichi Suzuki, Shoichiro Ohta, Kazunori Yoshikawa, Kazumasa Takao, Akiko Shimahara
  • Antibody capable of binding to specific region of periostin, and method of measuring periostin using the same
    Patent number: 9347954
    Abstract: The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: May 24, 2016
    Assignees: SHINO-TEST CORPORATION, SAGA UNIVERSITY, KURUME UNIVERSITY
    Inventors: Kenji Izuhara, Shoichiro Ohta, Kazuhiko Arima, Hiroshi Shiraishi, Shoichi Suzuki, Tomoaki Hoshino, Yoshinori Azuma, Junya Ono
  • ANTIBODY CAPABLE OF BINDING TO SPECIFIC REGION OF PERIOSTIN, AND METHOD FOR MEASURING PERIOSTIN USING SAME
    Publication number: 20140308685
    Abstract: The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin.
    Type: Application
    Filed: September 6, 2012
    Publication date: October 16, 2014
    Applicants: SHINO-TEST CORPORATION, KURUME UNIVERSITY, SAGA UNIVERSITY
    Inventors: Kenji Izuhara, Shoichiro Ohta, Kazuhiko Arima, Hiroshi Shiraishi, Shoichi Suzuki, Tomoaki Hoshino, Yoshinori Azuma, Junya Ono
  • METHOD FOR DIAGNOSING CHRONIC SINUSITIS
    Publication number: 20140273280
    Abstract: The present invention provides a method for detecting chronic sinusitis, which comprises measuring the concentration of a periostin protein in blood or nasal secretion collected from a test subject. Thereby, a method for detecting chronic sinusitis, which is capable of detecting chronic sinusitis more simply, more promptly and less invasively, is provided.
    Type: Application
    Filed: October 30, 2012
    Publication date: September 18, 2014
    Applicant: Saga University
    Inventors: Kenji Izuhara, Shoichiro Ohta, Kazuhiko Arima, Hiroshi Shiraishi, Shoichi Suzuki, Nobuo Ohta, Akihiro Ishida, Yusuke Suzuki
  • METHOD FOR DETECTION OF IDIOPATHIC INTERSTITIAL PNEUMONIA
    Publication number: 20130230861
    Abstract: The present invention provides a method for detecting idiopathic interstitial pneumonia, which comprises measuring the expression level of a periostin gene or the amount of a periostin protein in a biological sample. Thereby, a method for detecting idiopathic interstitial pneumonia using a marker is provided.
    Type: Application
    Filed: February 27, 2013
    Publication date: September 5, 2013
    Applicants: Kurume University, Saga University
    Inventors: Kenji IZUHARA, Shoichiro Ohta, Hiroshi Shiraishi, Hisamichi Aizawa, Tomoaki Hoshino, Masaki Okamoto
  • Method for detection of idiopathic interstitial pneumonia
    Patent number: 8420310
    Abstract: The present invention provides a method for detecting idiopathic interstitial pneumonia, which comprises measuring the expression level of a periostin gene or the amount of a periostin protein in a biological sample. Thereby, a method for detecting idiopathic interstitial pneumonia using a marker is provided.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: April 16, 2013
    Assignees: Saga University, Kurume University
    Inventors: Kenji Izuhara, Shoichiro Ohta, Hiroshi Shiraishi, Hisamichi Aizawa, Tomoaki Hoshino, Masaki Okamoto
  • METHOD FOR DETECTION OF IDIOPATHIC INTERSTITIAL PNEUMONIA
    Publication number: 20110086360
    Abstract: The present invention provides a method for detecting idiopathic interstitial pneumonia, which comprises measuring the expression level of a periostin gene or the amount of a periostin protein in a biological sample. Thereby, a method for detecting idiopathic interstitial pneumonia using a marker is provided.
    Type: Application
    Filed: June 3, 2009
    Publication date: April 14, 2011
    Inventors: Kenji Izuhara, Shoichiro Ohta, Hiroshi Shiraishi, Hisamichi Aizawa, Tomoaki Hoshino, Masaki Okamoto