Abstract: One of the purposes of the present invention is to provide a polysiloxane macromonomer which has high hydrophilicity and a narrow molecular weight distribution and is usable as a material for ophthalmic lenses. The present invention provides a both-terminal modified polysiloxane macromonomer represented by the following average structural formula [I?]: R?Me2SiO(Me2SiO)pSiMe2R???[I?] wherein R? represents —C3H6O(C2H4O)qC(?O)NH(C2H4O)rC(?O)C(Q)?CH2, Me is a methyl group, p is an integer of from 40 to 100, q is an integer of from 5 to 10, r is an integer of from 2 to 3 and Q is a methyl group or a hydrogen atom. The both-terminal modified polysiloxane macromonomer according to claim 1, having a molecular weight distribution, Mw/Mn, of 1.3 or less.

Abstract: One of the purposes of the present invention is to provide a polysiloxane macromonomer which has high hydrophilicity and a narrow molecular weight distribution and is usable as a material for ophthalmic lenses.

Abstract: One of the purposes of the present invention is to provide a polysiloxane macromonomer which has high hydrophilicity and a narrow molecular weight distribution and is usable as a material for ophthalmic lenses.

Abstract: One of the purposes of the present invention is to provide a polysiloxane macromonomer which has high hydrophilicity and a narrow molecular weight distribution and is usable as a material for ophthalmic lenses.

Abstract: A polysiloxane-based macromonomer for an ophthalmic lens, which exhibits excellent compatibility with respect to a hydrophilic component such as a hydrophilic monomer. The polysiloxane-based macromonomer has at least one polymerizable group, a polysiloxane chain having a siloxane unit as a repeating unit, a polyoxyethylene chain in which a number of repetition of an oxyethylene group is two or more, and a polyoxyalkylene chain having an oxyalkylene group other than the oxyethylene group as a repeating unit, wherein an HLB value calculated according to a formula: [HLB value]=E/5 is within a range from 0.7 to 6.0, wherein E represents a weight fraction (wt %) of the oxyethylene group in a molecule of the polysiloxane-based macromonomer.

Abstract: The present invention provides a silicone having a bis(trialkylsilyl)aminopropyl group at one terminal and represented by the following general formula [II]: R?R2SiO(R2SiO)mR2SiC3H6N(SiR3)2??[II] wherein m is an integer of from 1 to 200, R? is an alkyl group having 1 to 4 carbon atoms, and R is an alkyl group having 1 to 10 carbon atoms.

Abstract: The invention provides a TRIS-containing vinylic monomer which comprises one sole (meth)acryloyloxy group and a tris(trimethylsiloxy)silyl group covalently linked to the ethylenically-unsaturated group through a polyoxyethylene linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from a TRIS-containing vinylic monomer of the invention. In addition, the invention provides a method for making a TRIS-containing vinylic monomer of the invention.

Abstract: The invention provides a TRIS-containing vinylic monomer which comprises one sole (meth)acryloyloxy group and a tris(trimethylsiloxy)silyl group covalently linked to the ethylenically-unsaturated group through a polyoxyethylene linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from a TRIS-containing vinylic monomer of the invention. In addition, the invention provides a method for making a TRIS-containing vinylic monomer of the invention.

Abstract: The invention provides a TRIS-containing vinylic monomer which comprises one sole (meth)acryloyloxy group and a tris(trimethylsiloxy)silyl group covalently linked to the ethylenically-unsaturated group through a polyoxyethylene linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from a TRIS-containing vinylic monomer of the invention. In addition, the invention provides a method for making a TRIS-containing vinylic monomer of the invention.

Abstract: A polysiloxane-based macromonomer for an ophthalmic lens, which exhibits excellent compatibility with respect to a hydrophilic component such as a hydrophilic monomer. The polysiloxane-based macromonomer has at least one polymerizable group, a polysiloxane chain having a siloxane unit as a repeating unit, a polyoxyethylene chain in which a number of repetition of an oxyethylene group is two or more, and a polyoxyalkylene chain having an oxyalkylene group other than the oxyethylene group as a repeating unit, wherein an HLB value calculated according to a formula: [HLB value]=E/5 is within a range from 0.7 to 6.0, wherein E represents a weight fraction (wt %) of the oxyethylene group in a molecule of the polyxiloxane-based macromonomer.

Abstract: One of the purposes of the present invention is to provide a compound which is a polymerizable monomer having a specific number of silicon atoms and a specific number of fluorine atoms and to provide a method for preparing the compound. The present invention provides a compound represented by the following formula (1): wherein m is an integer of from 2 to 10, n is an integer of from 1 to 3, R1 is, independently of each other, an alkyl group having 1 to 6 carbon atoms, and R2 is, independently of each other, an alkylene group having 1 to 6 carbon atoms or a fluoroalkylene group having 1 to 6 carbon atoms, R3 is an alkyl group having 1 to 4 carbon atoms, and R4, R5 and R6 are, independently of each other, a hydrogen atom or a methyl group.

Abstract: One of the purposes of the present invention is to provide a compound which is a polymerizable monomer having a specific number of silicon atoms and a specific number of fluorine atoms, has a higher purity, is suitable as an ophthalmic monomer, is well compatible with another (meth)acryl monomer, and provides a polymer having excellent hydrophilicity, anti-staining property and durability of mechanical strength and to provide a method for preparing the compound. The present invention provides a compound represented by the following formula (1). Further, the present invention provides a method for preparing the compound, a polymer having repeating units derived from the aforesaid compound and an ophthalmic device composed of the polymer.

Abstract: One of the purposes of the present invention is to provide a silicone compound which has a specific number of silicon atoms, is well compatible with (meth)acryl monomers, is suitable as an ophthalmic monomer and provides a polymer having excellent durability of mechanical strength in a buffered phosphate solution. Another purpose of the present invention is to provide a silicone compound which functions well as a crosslinking agent for a polymerizable monomer. Further, another purpose is to provide a method for preparing the silicone compound, in particular the silicone compound having one specific structure at a high ratio. In the first aspect, the present invention provides a compound represented by the following formula (1-1): and a method for preparing the silicone compound. In the second aspect, the present invention provides a compound represented by the following formula (2-1): and a method for preparing the silicone compound.

Abstract: A purpose of the present invention is to provide a polymerizable group-containing silicone compound which is liquid at room temperature, has good handling properties and compatibility with other polymerizable monomers. The present invention provides a silicone compound represented by the general formula (1) which has a structure represented by the following formula (2) or (3): wherein Rc is an alkyl group having 1 to 10 carbon atoms and Z is a radical-polymerizable group; wherein p1 and p2 are, independently of each other, positive integers such that a total number of p1 and p2 is 3 to 10, and Z is a radical-polymerizable group; and has a silicone structure bonded to the aforesaid formula (2) or (3) via a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms. The present invention further provides a method for preparation the aforesaid silicone compound.

Abstract: One of the purposes of the present invention is to provide a compound which is a polymerizable monomer having a specific number of silicon atoms and a specific number of fluorine atoms, has a higher purity, is suitable as an ophthalmic monomer, is well compatible with another (meth)acryl monomer, and provides a polymer having excellent hydrophilicity, anti-staining property and durability of mechanical strength and to provide a method for preparing the compound. The present invention provides a compound represented by the following formula (1). Further, the present invention provides a method for preparing the compound, a polymer having repeating units derived from the aforesaid compound and an ophthalmic device composed of the polymer.

Abstract: The invention provides a TRIS-containing vinylic monomer which comprises one sole (meth)acryloyloxy group and a tris(trimethylsiloxy)silyl group covalently linked to the ethylenically-unsaturated group through a polyoxyethylene linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from a TRIS-containing vinylic monomer of the invention. In addition, the invention provides a method for making a TRIS-containing vinylic monomer of the invention.

Abstract: One of the purposes of the present invention is to provide a compound which is a polymerizable monomer having a specific number of silicon atoms and a specific number of fluorine atoms and to provide a method for preparing the compound. The present invention provides a compound represented by the following formula (1): wherein m is an integer of from 2 to 10, n is an integer of from 1 to 3, R1 is, independently of each other, an alkyl group having 1 to 6 carbon atoms, and R2 is, independently of each other, an alkylene group having 1 to 6 carbon atoms or a fluoroalkylene group having 1 to 6 carbon atoms, R3 is an alkyl group having 1 to 4 carbon atoms, and R4, R5 and R6 are, independently of each other, a hydrogen atom or a methyl group.

Abstract: One of the purposes of the present invention is to provide a silicone compound which has a specific number of silicon atoms, is well compatible with (meth)acryl monomers, is suitable as an ophthalmic monomer and provides a polymer having excellent durability of mechanical strength in a buffered phosphate solution. Another purpose of the present invention is to provide a silicone compound which functions well as a crosslinking agent for a polymerizable monomer. Further, another purpose is to provide a method for preparing the silicone compound, in particular the silicone compound having one specific structure at a high ratio. In the first aspect, the present invention provides a compound represented by the following formula (1-1): and a method for preparing the silicone compound. In the second aspect, the present invention provides a compound represented by the following formula (2-1): and a method for preparing the silicone compound.

Abstract: A dual end glycerol (meth)acrylate-modified silicone having formula (I): R1Me2SiO(R22SiO)aSiMe2R1 is novel. R1 is a mixture of 70-95 mol % of a group having formula (i) and 30-5 mol % of a group having formula (ii) wherein R3 is H or methyl, R2 is a monovalent hydrocarbon group which may be halogenated, Me stands for methyl, and a is an integer of 10-300.

Abstract: A purpose of the present invention is to provide a polymerizable group-containing silicone compound which is liquid at room temperature, has good handling properties and compatibility with other polymerizable monomers. The present invention provides a silicone compound represented by the general formula (1) which has a structure represented by the following formula (2) or (3): wherein Rc is an alkyl group having 1 to 10 carbon atoms and Z is a radical-polymerizable group; wherein p1 and p2 are, independently of each other, positive integers such that a total number of p1 and p2 is 3 to 10, and Z is a radical-polymerizable group; and has a silicone structure bonded to the aforesaid formula (2) or (3) via a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms. The present invention further provides a method for preparation the aforesaid silicone compound.