Abstract: An ocular symptom-improving agent which is a composition containing a culture supernatant of dental pulp-derived stem cells or immortalized stem cells thereof and which is used for improving a symptom of myopia, astigmatism, presbyopia, eye fatigue or blurred vision is a novel ocular symptom-improving agent.

Abstract: An agent for improving cancer cachexia used for administration to a subject with cancer cachexia which is a composition containing a culture supernatant of dental pulp-derived stem cells and in which the culture supernatant contains microparticles derived from the dental pulp-derived stem cells is a novel agent for improving cancer cachexia.

Abstract: A purpose is to provide a health management system that can support the health of each patient safely and continuously by collaborating with exercise and nutrition specialists. In a health management system, a service providing server, a doctor server, and a client terminal share information data via a network. The client terminal is provided with an identification information registration means, a medical interview information registration means, and an information transmission means. The service providing server is provided with a guidance instruction issuance request means for transmitting an issuance request for guidance instruction data regarding exercise prescription and nutrition prescription by a doctor to the doctor server. The doctor server is provided with a guidance instruction automatic creation means, a guidance instruction manual correction means, and a guidance instruction issuance means based on the information data obtained from the guidance instruction issuance request means.

Abstract: A cytokine storm suppressor containing microparticles derived from a culture supernatant of dental pulp-derived stem cells, adipose-derived stem cells, bone marrow-derived stem cells, umbilical cord-derived stem cells or immortalized stem cells thereof in which the microparticles contain extracellular superoxide dismutase (SOD3) in an effective amount capable of repairing a tissue or a cell damaged by a cytokine storm or a higher amount and which is used for administration to a human or a nonhuman animal with a cytokine storm before damage of a tissue is caused by the cytokine storm to suppress the tissue damage by the cytokine storm through suppression of the cytokine storm or used for administration to a human or a nonhuman animal with damage of a tissue caused by a cytokine storm to repair the tissue damaged by the cytokine storm through suppression of the cytokine storm; a method for using the cytokine storm suppressor; and a screening method.

Abstract: A testicular function-improving agent which contains microparticles derived from a culture supernatant of dental pulp-derived stem cells, adipose-derived stem cells or immortalized stem cells thereof and in which the improvement of a testicular function is improvement of the ability of a testis itself to form sperm, improvement of the function of sperm themselves obtained from a testis, improvement of the function of sperm obtained from a testis of acting on a female, rejuvenation of any of the functions that has aged with aging or activation of sperm through addition to semen taken out of the body of an animal can significantly improve a testicular function of an animal.

Abstract: A composition containing a culture supernatant of dental pulp-derived stem cells, adipose-derived stem cells, umbilical cord-derived stem cells or immortalized stem cells thereof in which the composition contains angiotensin-converting enzyme 2 (ACE2) and is used for administration to a healthy person or a healthy animal for preventing infection of the healthy person or the healthy animal with a virus that uses ACE2 as a receptor can be used as a medicine for preventing infection with a virus that uses ACE2 as a receptor, such as COVID-19, or the like when administered to a healthy person or a healthy animal.

Abstract: Provided are a cell growth method including serum-free culture of somatic cells sowed in a cell growth medium containing a culture supernatant of dental pulp stem cells, wherein the somatic cells exclude physically or physiologically defected somatic cells, is a novel cell growth method for serum-free culture of somatic cells.

Abstract: A notification server, notification method and notification program to perform watch over a person to be watched who uses on-demand transportation. A transceiver part receives boarding/alighting information comprised of a date and time of boarding/alighting, a stopping point of a vehicle and a name of a boarding person or a name of alighting person transmitted from an information terminal apparatus mounted on a shared vehicle, and a notification information generating part acquires a notifying destination associated with the received name of the boarding person or the name of the alighting person from a notifying destination storage part and generates notification information addressing to the acquired notifying destination, and a transceiver part transmits the generated notification information.

Abstract: An ultrasonic endoscope has an ultrasonic probe, an observation optical system and a channel for inserting a medical instrument. A transurethral diagnostic method using the ultrasonic endoscope comprising step of inserting an insertion portion of the ultrasonic endoscope toward a target diagnostic portion through a urethral, step of starting transmission of an ultrasonic wave from the ultrasonic probe which has reached the vicinity of the target diagnostic portion and displaying at least a B-mode image of the target diagnostic portion on a screen, step of identifying a puncture position from the B-mode image displayed on the screen, and step of puncturing the puncture position identified on the screen with a medical instrument through the channel for inserting the medical instrument.

Abstract: Valves 4,5 are disposed in such a portion which is defined in an end portion of a piston 30 of an adjusting cylinder body 1 and which does not contact a load giving body 7, thereby preventing deformation by compression caused in incorporation positions of the valves 4,5 and leakage of a filling within the cylinder body 1.