Patents by Inventor Shoji Omoto

Shoji Omoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4932449
    Abstract: A joint planer has a chute for guiding chips resulting from a planing operation to a dust collector guide. The chute is attached to a vertically-movable table near its work surface and extends to the upper edge of the dust collector guide, which is below the planer cutting barrel. The lower end of the chute slides up and down against the edge of the dust collector guide with movement of the vertical table, thereby maintaining a closed path from the surface to the dust collector guide.
    Type: Grant
    Filed: September 12, 1989
    Date of Patent: June 12, 1990
    Assignee: Ryobi Ltd.
    Inventor: Shoji Omoto
  • Patent number: 4316894
    Abstract: A new antibiotic SF-1130-x.sub.3 substance is produced by cultivating a microorganism Streptomyces myxogenes SF-1130 (deposited under FERM-P. 676 and ATCC 31305) in a liquid culture medium under aerobic conditions, and this antibiotic may be isolated from the fermentation broth of said microorganism and is useful as an inhibitor to .alpha.-glucosidase and saccharase. Besides, this antibiotic, when orally given, is useful as a drug for suppressing an elevation in the level of blood sugar in living animals which have taken starch and/or sugars.
    Type: Grant
    Filed: September 9, 1980
    Date of Patent: February 23, 1982
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Shoji Omoto, Jiro Itoh, Tomizo Niwa, Takashi Shomura, Tetsutaro Niizato, Shigeharu Inouye
  • Patent number: 4302580
    Abstract: A chemotherapeutic, antibacterial agent, 7.beta.-[(2D-2-amino-2-carboxy)ethylthioacetamido]-7.alpha.-methoxy-3-[(1- methyl-1H-tetrazole-5-yl)thiomethyl]-3-cephem-4-carboxylic acid is produced economically and efficiently starting from cephamycin A and/or B by a "new route" process comprising the consecutive steps of reaction of cephamycin with 5-mercapto-1-methyl-1H-tetrazole; protection of the terminal amino group thereof by acylation; protection of the two carboxyl groups thereof by esterification; replacement of the acyl group initially having attached to the 7-amino group by a halogenoacetyl group; deprotection of the blocked 4-carboxyl group; and condensation of D-cysteine with the halogenoacetyl group attaching to the 7-amino group.
    Type: Grant
    Filed: September 9, 1980
    Date of Patent: November 24, 1981
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Katsuyoshi Iwamatsu, Jiro Itoh, Shoji Omoto, Takashi Tsuruoka, Shigeharu Inouye
  • Patent number: 4242327
    Abstract: New antibiotic, SF-2052 substance is produced by cultivating a microorganism, Dactylosporangium matsuzakiense SF-2052 now deposited under FERM-P 4670 or ATCC No. 31570 in a liquid culture medium under aerobic conditions, and this antibiotic may be isolated from the culture broth by conventional method and is useful as antibacterial agent.
    Type: Grant
    Filed: October 31, 1979
    Date of Patent: December 30, 1980
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Kazunori Ohba, Takashi Shomura, Michio Kojima, Shoji Omoto, Takashi Tsuruoka, Shigeharu Inoue
  • Patent number: 4169140
    Abstract: A new antibiotic SF-1771 substance is produced by cultivating a new strain, Streptomyces toyocaensis SF-1771, in a liquid culture medium under aerobic conditions. This antibiotic may be isolated from the fermentation broth by treating the broth filtrate with a synthetic adsorbent resin for adsorption of the active compound and eluting the resin with an aqueous alcohol or aqueous acetone, followed by chromatographic purification. SF-1771 substance is a copper-containing antibiotic which shows antibacterial activity against Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis. Removal of the copper component from SF-1771 substance by treatment with hydrogen sulfide, an alkali metal sulfide or a copper-chelating agent gives SF-1771-B substance containing no copper component which shows antibacterial activity as high as but a toxicity lower than SF-1771 substance.
    Type: Grant
    Filed: October 27, 1976
    Date of Patent: September 25, 1979
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Kazunori Ohba, Takashi Shomura, Hiroshi Watanabe, Kunikazu Totsukawa, Michio Kojima, Shoji Omoto, Takashi Tsuruoka, Shigeharu Inoue, Taro Niida
  • Patent number: 4160026
    Abstract: New antibiotics SF-1130-x.sub.1 substance and SF-1130-x.sub.2 substance are produced by cultivating a microorganism Streptomyces myxogenes SF-1130 now deposited under FERM-P. 676 and ATCC. 31305 in a liquid culture medium under aerobic conditions, and these antibiotics may be isolated from the fermentation broth and are useful as an activator for enhancing the host defense system in living animals. The activity of these antibiotics may be improved when used in combination with one or more of maltose, maltotriose, maltotetraose, maltopentaose, maltohexaose and maltoheptaose.
    Type: Grant
    Filed: August 22, 1977
    Date of Patent: July 3, 1979
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Katsuyoshi Iwamatsu, Shoji Omoto, Takashi Shomura, Hiroshi Watanabe, Michio Kojima, Shigeharu Inoue, Taro Niida, Takashi Hisamatsu, Shingo Uchida
  • Patent number: 4151041
    Abstract: Maltopentaose and maltohexaose are produced with commercial advantage by cultivation of Streptomyces myxogenes SF-1130 strain under aerobic conditions in an appropriate culture medium and recovery from the resultant culture.
    Type: Grant
    Filed: August 22, 1977
    Date of Patent: April 24, 1979
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Katsuyoshi Iwamatsu, Shoji Omoto, Takashi Shomura, Shigeharu Inoue, Taro Niida, Takashi Hisamatsu, Singo Uchida
  • Patent number: 4029881
    Abstract: A new derivative of the macrolide antibiotic SF-837 substance is manufactured by treating a 9,2'-diacyl- or 9-acyl-SF-837 composition with dimethylsulfoxide and acetic anhydride, and, subsequently, with an alcohol or water-containing solvent to yield the novel compound, 9-Acyl-3"-thiomethoxymethyl-SF-837 composition. In addition to high therapeutic effectiveness and low acute toxicity, this novel compound of the present invention has the great advantages that it does not have the bitter taste originally accompanying the parent compounds, and the further advantage that it is suitable for pediatric and veterinary use.
    Type: Grant
    Filed: March 28, 1973
    Date of Patent: June 14, 1977
    Assignee: Meiji Seika Co., Ltd.
    Inventors: Shigeharu Inouye, Shoji Omoto, Taro Niida, Bunzo Nomiya
  • Patent number: 4017607
    Abstract: As new compounds are provided 9,3",4"-trialkanoyl SF-837 M.sub.1 substances which have therapeutically useful antibacterial activity and do not show any objectionable long-lasting bitter taste upon its oral administration. These 9,3",4"-trialkanoyl SF-837 M.sub.1 substances may be prepared from SF-837 substance, 9,2',3"-tri-acetyl SF-837 M.sub.1 substance, 9,2'-di-acetyl SF-837 substance, 9-propionyl SF-837 substance or 9,2'-dipropionyl SF-837 substance by acylating the latter with an alkanoic acid anhydride at 50.degree.-120.degree. C to produce the corresponding 9,2',3",4"-tetra-alkanoyl SF-837 M.sub.1 substance and occasionally the 9,18,2',3",4"-penta-alkanoyl SF-837 M.sub.1 substance, with involving the shift of the 4"-alkanoyl group to the 3"-hydroxyl group. Partial and selective hydrolysis of the 9,2',3",4"-tetra-alkanoyl SF-837 M.sub.1 substance and/or the 9,18,2',3",4"-penta-alkanoyl SF-837 M.sub.1 substance so produced gives the desired 9,3",4"-tri-alkanoyl SF-837 M.sub.1 substance.
    Type: Grant
    Filed: July 18, 1975
    Date of Patent: April 12, 1977
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Shigeharo Inouye, Shoji Omoto, Katsuyoshi Iwamatsu, Takashi Tsuruoka, Taro Niida, Toyoaki Kawasaki
  • Patent number: 3959256
    Abstract: A 9-O-alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance is now synthetized, which is a new compound useful in that this new 9-O-alkanoyl-3"-O-alkanoyloxymethyl derivative of the SF-837 substance exhibits an antibacterial activity comparable to that of the parent SF-837 substance but is advantageously free from the unpleasant bitter taste inherent to the SF-837 substance and is hence adapted for oral administration. A process of producing the 9-O-alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance is also provided, which comprises hydrolysing partially and selectively a 9,2'-di-O-alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance in an aqueous alkanol or aqueous acetone. The 9,2'-di-O-alkanoyl-3"-O-alkanopyloxymethyl-SF-837 substance may be prepared by reacting a 9,2'-di-alkanoyl- or O-mono-O-alkanoyl-3"-O-thiomethoxymethyl-SF-837 substance with an alkanoic anhydride which is exemplified by acetic anhydride or propionic anhydride in the specification.
    Type: Grant
    Filed: September 12, 1974
    Date of Patent: May 25, 1976
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Shigeharu Inouye, Shoji Omoto, Katsuyoshi Iwamatsu, Taro Niida, Toyoaki Kawasaki, Takashi Tsuruoka
  • Patent number: 3940479
    Abstract: A BN-109 substance producing strain of the genus Bacillus is cultivated under an aerobic condition to produce and accumulate BN-109 substance in a culture medium. The BN-109 substance is isolated from the culture broth and purified, and proved to be a novel antibiotic. The BN-109 is effective in the treatment and prevention of swine scours.
    Type: Grant
    Filed: July 17, 1974
    Date of Patent: February 24, 1976
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Takashi Shomura, Shoji Omoto, Shinji Miyado, Hiroshi Watanabe, Shigeharu Inouye, Yujiro Yamada, Taro Niida