Abstract: A flowpath switch valve is configured for extended service life by spreading the region, of the sliding surfaces of a stator and a rotor, that is subject to wear over the entirety of the sliding surfaces. The stator has fixed stator flowpaths, and the rotor has rotor flowpaths. A flowpath switch valve, depending on the rotor rotation state, realizes connection patterns that include: a first connection pattern wherein a rotor flowpath 241 connects a fixed stator flowpath 31 and a fixed stator flowpath 32; a second connection pattern wherein the rotor flowpath 241 connects the fixed stator flowpath 31 and a fixed stator flowpath 36; a third connection pattern wherein a rotor flowpath 242 connects the fixed stator flowpath 31 and the fixed stator flowpath 32; and a fourth connection pattern wherein the rotor flowpath 242 connects the fixed stator flowpath 31 and the fixed stator flowpath 36.

Abstract: To provide a liquid chromatograph and a liquid delivery method capable of more easily and reliably removing bubbles mixed during mobile phase installation or replacement operation.

Abstract: A liquid chromatography (LC) that can supply a mobile phase to a storage bottle and can prevent mixing of air bubbles into a flow path without stopping analysis and liquid feeding. The LC includes a liquid feeding device that feeds out a mobile phase, a sample injection portion that injects a sample into the mobile phase, a column that separates the sample carried by the mobile, and a detection device that detects the sample. The LC further comprises a storage bottle that stores the mobile phase fed by the liquid feeding device, a mobile phase supply bottle that supplies the mobile phase to the storage bottle, a mobile phase supply pump that supplies the mobile phase to the storage bottle, and a control unit that controls an operation of the mobile phase supply pump and determines an amount of the mobile phase to be supplied to the storage bottle.

Abstract: A technique for replacing a separation column includes: a driving device supporting a first pipe along a first direction; a fixing member that fixes a second pipe to be opposed to the first pipe along the first direction; a column case between the first pipe and the second pipe, having a first and second holes communicating with the first and second pipes, respectively; and an interlocking mechanism that moves the column case in the first direction in conjunction with movement of the first pipe. The column case allows a column cartridge retaining a separation column to be connected and disconnected. The driving device moves the first pipe and the interlocking mechanism such that two states are reversibly taken; a closed state in which the separation column is between the first and second pipes and an open state in which the first and second pipes are positioned outside the column case.

Abstract: An automatic analyzer 1 includes a reagent bottle installation unit 200 that installs a reagent bottle 301 containing a reagent used for analysis; a nozzle unit 210 that couples a supply flow path 220 that connects a location where the reagent is used and the inside of the reagent bottle 301 installed in the reagent bottle installation unit 200 to the reagent bottle 301; and a stopper 202 that is disposed on the movement path of a reagent aspiration nozzle 400 of the nozzle unit 210 and prevents the reagent aspiration nozzle 400 from being inserted into the reagent bottle 301. This automatic analyzer realizes the prevention of misplacement of reagent types and the prevention of removal of the reagents at the incorrect timing with less space and constituent components.

Abstract: A flowpath switch valve is configured for extended service life by spreading the region, of the sliding surfaces of a stator and a rotor, that is subject to wear over the entirety of the sliding surfaces. The stator has fixed stator flowpaths, and the rotor has rotor flowpaths. A flowpath switch valve, depending on the rotor rotation state, realizes connection patterns that include: a first connection pattern wherein a rotor flowpath 241 connects a fixed stator flowpath 31 and a fixed stator flowpath 32; a second connection pattern wherein the rotor flowpath 241 connects the fixed stator flowpath 31 and a fixed stator flowpath 36; a third connection pattern wherein a rotor flowpath 242 connects the fixed stator flowpath 31 and the fixed stator flowpath 32; and a fourth connection pattern wherein the rotor flowpath 242 connects the fixed stator flowpath 31 and the fixed stator flowpath 36.

Abstract: A liquid-mixing device that minimizes solvent leakage and reduces creep of or damage to the component parts of said liquid-mixing device even at ultrahigh pressures of 100 MPa and up. Also, a liquid chromatography device using said liquid-mixing device. Said liquid chromatography device is provided with a supply pump that supplies a plurality of different solutions, a liquid-mixing device that mixes the supplied solutions, a sample injection device that injects a sample into the mixture of solutions, a column that separates the components of the injected sample, and a detector that detects the separated components. The liquid-mixing device has an inlet-side connector through which the plurality of different solutions flow in, a liquid-mixing section in which said solutions are mixed, and an outflow-side connector through which the mixed solutions flow out.

Abstract: A pipe connection joint which is repeatedly usable when an analysis column is replaced with another in a liquid chromatographic device. To this end, an elastic body is built into a compression screw for inserting a pipe passed through a ferrule into the analysis column to thereby axially movably support the pipe, and a pipe clamp is secured in advance at a predetermined position of the pipe. A distance between the ferrule and the pipe clamp changes on the basis of the length of a portion of the pipe sticking out from the ferrule and the pressing force of the elastic body applied to the pipe.

Abstract: A liquid-mixing device that minimizes solvent leakage and reduces creep of or damage to the component parts of said liquid-mixing device even at ultrahigh pressures of 100 MPa and up. Also, a liquid chromatography device using said quid-mixing device. Said liquid chromatography device is provided with a supply pump that supplies a plurality of different solutions, a liquid-mixing device that mixes the supplied solutions, a sample injection device that injects a sample into the mixture of solutions, a column that separates the components of the injected sample, and a detector that detects the separated components. The liquid-mixing device has an inlet-side connector through which the plurality of different solutions flow in, a liquid-mixing section in which said solutions are mixed, and an outflow-side connector through which the mixed solutions flow out.

Abstract: The present invention provides a pipe connection joint which is repeatedly usable when an analysis column or the like is replaced with another in a liquid chromatographic device. To this end, an elastic body is built into a compression screw for inserting a pipe passed through a ferrule into the analysis column to thereby axially movably support the pipe, and a pipe clamp is secured in advance at a predetermined position of the pipe. A distance between the ferrule and the pipe clamp changes on the basis of the length of a portion of the pipe sticking out from the ferrule and the pressing force of the elastic body applied to the pipe. Consequently, in a liquid chromatographic device, a pipe connection joint for the analysis column or the like can be repeatedly used of plural times.

Abstract: A sample rack 1 in which sample holding container 6 containing sample liquid is loaded and cooled via a cooling device 8 includes containing sections 40 adapted to receive the sample holding containers 6, and groove portions 11 disposed with inclination below the bottom surface of the containing section 40. The bottom surface of the containing section 40 communicates with the groove portion 11. The dew condensation water introduced into the groove portion 11 is discharged to the outside of the sample rack 1 via an opening portion 12 provided on the side surface of the sample rack 1. In this way, since the dew condensation water is forcibly discharged, workability encountered during removal of the sample rack and sample cooling capacity can be improved.

Abstract: An apparatus capable of improving image quality by making it possible to suck specimens of different sizes electrostatically, and uniformalizing an electric field of a specimen edge portion, while suppressing increase in prime cost is provided. Specimen holding means is an electrostatic chuck, a master flat plane part surrounding a specimen of the largest size of specimen sizes, and an opening surrounding a specimen size except for the largest specimen size are included at an outer peripheral portion of the electrostatic chuck, a dummy specimen attachable to and detachable from the electrostatic chuck is included, and at a time of switching the specimen size, a dummy specimen is selected (or may be prevented from being used).