Patents by Inventor Shokichi Matsunami
Shokichi Matsunami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6803207Abstract: A method or an apparatus for selecting oocytes or eggs based on at least one objective criterion, such as membrane potential, comprises a step or means for selecting a plurality of oocytes or eggs having a certain size with a filter or the like, and a step or means for measuring a membrane potential of each of the oocytes or eggs thereby sorting out those with a membrane potential within a specified range. The selected oocytes or eggs are sold or transferred together with the measurement information or an injected sample of interest.Type: GrantFiled: May 15, 2002Date of Patent: October 12, 2004Assignee: Hitachi, Ltd.Inventors: Tomoko Takeshita, Jun Otomo, Shokichi Matsunami
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Publication number: 20040180428Abstract: An apparatus for microinjection of samples into amphibian oocytes, comprising a tray for holding a plurality of the amphibian oocytes, an injection needle for injecting a sample into the said amphibian oocytes, a driving means for moving a relative position between the said tray and the said injection needle and a controlling means for controlling the said movement by imputing a depth of the said injection needle for the said tray or the said amphibian oocytes in the injection of the sample, and injecting the sample into the said amphibian oocytes at the said depth.Type: ApplicationFiled: March 31, 2004Publication date: September 16, 2004Applicant: Hitachi, LtdInventors: Tomoko Takeshita, Jun Otomo, Sayuri Nomura, Shokichi Matsunami, Noboru Moriya, Sakae Saito
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Patent number: 6593129Abstract: An apparatus for microinjection of samples into amphibian oocytes, comprising a tray for holding a plurality of the amphibian oocytes, an injection needle for injecting a sample into the said amphibian oocytes, a driving means for moving a relative position between the said tray and the said injection needle and a controlling means for controlling the said movement by imputing a depth of the said injection needle for the said tray or the said amphibian oocytes in the injection of the sample, and injecting the sample into the said amphibian oocytes at the said depth. According to the present invention, the sample can be injected into the amphibian oocyte with constant depth.precisely and quality of oocyte or a positional site of needle injection can be recorded as the information.Type: GrantFiled: September 20, 2000Date of Patent: July 15, 2003Assignee: Hitachi, Ltd.Inventors: Tomoko Takeshita, Jun Otomo, Sayuri Nomura, Shokichi Matsunami, Noboru Moriya, Sakae Saito
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Patent number: 6539244Abstract: An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided. A glass electrode 103 in the air is moved toward a Xenopus Oocyte 601 held in a cell. Changes in the potential states of the glass electrodes are picked up by a control computer to distinguish the relative positions of the glass electrode 102 and the Xenopus Oocyte 601, and the sequence of electrophysiological measurement so as to penetrate the glass electrode 102 into the Xenopus Oocyte 601, hold the membrane potential and automatically administer the medicine.Type: GrantFiled: December 21, 2000Date of Patent: March 25, 2003Assignee: Hitachi, Ltd.Inventors: Hirokazu Kato, Jun Otomo, Sayuri Nomura, Tomoko Takeshita, Sakae Saito, Shokichi Matsunami, Noboru Moriya
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Publication number: 20030028908Abstract: An apparatus for microinjection of samples into amphibian oocytes incorporates a tray for holding a plurality of the amphibian oocytes, an injection needle for injecting a sample into the amphibian oocytes, a driving means for moving a relative position between the tray and the injection needle and a controlling device for controlling the movement by inputting a depth of the injection needle for the tray or the amphibian oocytes in the injection of the sample, and injecting the sample into the amphibian oocytes at the given depth. According to the present invention, the sample can be injected into the amphibian oocyte with constant depth precisely , and quality of the oocytes and the positional site of needle injection can be recorded as information.Type: ApplicationFiled: October 7, 2002Publication date: February 6, 2003Applicant: Hitachi, Ltd.Inventors: Tomoko Takeshita, Jun Otomo, Sayuri Nomura, Shokichi Matsunami, Noboru Moriya, Sakae Saito
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Publication number: 20030008384Abstract: A method or an apparatus for selecting oocytes or eggs based on at least one objective criterion, such as membrane potential, comprises a step or means for selecting a plurality of oocytes or eggs having a certain size with a filter or the like, and a step or means for measuring a membrane potential of each of the oocytes or eggs thereby sorting out those with a membrane potential within a specified range. The selected oocytes or eggs are sold or transferred together with the measurement information or an injected sample of interest.Type: ApplicationFiled: May 15, 2002Publication date: January 9, 2003Applicant: Hitachi, Ltd.Inventors: Tomoko Takeshita, Jun Otomo, Shokichi Matsunami
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Patent number: 6468784Abstract: A method or an apparatus for selecting oocytes or eggs based on at least one objective criterion, such as membrane potential, comprises a step or means for selecting a plurality of oocytes or eggs having a certain size with a filter or the like, and a step or means for measuring a membrane potential of each of the oocytes or eggs thereby sorting out those with a membrane potential within a specified range. The selected oocytes or eggs are sold or transferred together with the measurement information or an injected sample of interest.Type: GrantFiled: December 20, 2001Date of Patent: October 22, 2002Assignee: Hitachi, Ltd.Inventors: Tomoko Takeshita, Jun Otomo, Shokichi Matsunami
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Patent number: 6470201Abstract: An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided. A glass electrode 103 in the air is moved toward a Xenopus Oocyte 601 held in a cell. Changes in the potential states of the glass electrodes are picked up by a control computer to distinguish the relative positions of the glass electrode 102 and the Xenopus Oocyte 601 and the sequence of electrophysiological measurement so as to penetrate the glass electrode 102 into the Xenopus Oocyte 601, hold the membrane potential and automatically administer the medicine.Type: GrantFiled: March 6, 2001Date of Patent: October 22, 2002Assignee: Hitachi, Ltd.Inventors: Hirokazu Kato, Jun Otomo, Sayuri Nomura, Tomoko Takeshita, Sakae Saito, Shokichi Matsunami, Noboru Moriya
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Publication number: 20010011154Abstract: An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided.Type: ApplicationFiled: March 6, 2001Publication date: August 2, 2001Applicant: Hitachi, Ltd.Inventors: Hirokazu Kato, Jun Otomo, Sayuri Nomura, Tomoko Takeshita, Sakae Saito, shokichi Matsunami, Noboru Moriya
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Publication number: 20010005774Abstract: An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided.Type: ApplicationFiled: December 21, 2000Publication date: June 28, 2001Inventors: Hirokazu Kato, Jun Otomo, Sayuri Nomura, Tomoko Takeshita, Sakae Saito, Shokichi Matsunami, Noboru Moriya
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Patent number: 5976338Abstract: Arranging a pair of temperature control units on both sides of gel 1 and arranging light-transmitting slit 134 on one of the elements, irradiation of an excitation beam over the gel 1 and signal detection are practiced through the slit 134. Introducing dry air onto the slit part, mildew occurrence is prevented on the detecting part. Detecting the power level applied to the gel and calculating the temperature of the temperature control units so that the gel temperature might be a predetermined temperature, on the basis of the detected power level, thereafter carrying out the feedback control of the power level, the gel temperature can be controlled appropriately and strictly during electrophoresis in an automatic fluorescent electrophoresis system, so that high-speed analysis can be done highly reproducibly at a higher voltage applied even by SSCP.Type: GrantFiled: April 22, 1997Date of Patent: November 2, 1999Assignees: Hitachi, Ltd., Hitachi Electronics Engineering Co., Ltd.Inventors: Takeshi Fujita, Masaharu Kiyama, Shin-ichiro Umemura, Takamichi Muramatsu, Yuusuke Miyazaki, Masao Kamahori, Noboru Moriya, Shokichi Matsunami