Patents by Inventor Shokichi Matsunami

Shokichi Matsunami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6803207
    Abstract: A method or an apparatus for selecting oocytes or eggs based on at least one objective criterion, such as membrane potential, comprises a step or means for selecting a plurality of oocytes or eggs having a certain size with a filter or the like, and a step or means for measuring a membrane potential of each of the oocytes or eggs thereby sorting out those with a membrane potential within a specified range. The selected oocytes or eggs are sold or transferred together with the measurement information or an injected sample of interest.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: October 12, 2004
    Assignee: Hitachi, Ltd.
    Inventors: Tomoko Takeshita, Jun Otomo, Shokichi Matsunami
  • Publication number: 20040180428
    Abstract: An apparatus for microinjection of samples into amphibian oocytes, comprising a tray for holding a plurality of the amphibian oocytes, an injection needle for injecting a sample into the said amphibian oocytes, a driving means for moving a relative position between the said tray and the said injection needle and a controlling means for controlling the said movement by imputing a depth of the said injection needle for the said tray or the said amphibian oocytes in the injection of the sample, and injecting the sample into the said amphibian oocytes at the said depth.
    Type: Application
    Filed: March 31, 2004
    Publication date: September 16, 2004
    Applicant: Hitachi, Ltd
    Inventors: Tomoko Takeshita, Jun Otomo, Sayuri Nomura, Shokichi Matsunami, Noboru Moriya, Sakae Saito
  • Patent number: 6593129
    Abstract: An apparatus for microinjection of samples into amphibian oocytes, comprising a tray for holding a plurality of the amphibian oocytes, an injection needle for injecting a sample into the said amphibian oocytes, a driving means for moving a relative position between the said tray and the said injection needle and a controlling means for controlling the said movement by imputing a depth of the said injection needle for the said tray or the said amphibian oocytes in the injection of the sample, and injecting the sample into the said amphibian oocytes at the said depth. According to the present invention, the sample can be injected into the amphibian oocyte with constant depth.precisely and quality of oocyte or a positional site of needle injection can be recorded as the information.
    Type: Grant
    Filed: September 20, 2000
    Date of Patent: July 15, 2003
    Assignee: Hitachi, Ltd.
    Inventors: Tomoko Takeshita, Jun Otomo, Sayuri Nomura, Shokichi Matsunami, Noboru Moriya, Sakae Saito
  • Patent number: 6539244
    Abstract: An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided. A glass electrode 103 in the air is moved toward a Xenopus Oocyte 601 held in a cell. Changes in the potential states of the glass electrodes are picked up by a control computer to distinguish the relative positions of the glass electrode 102 and the Xenopus Oocyte 601, and the sequence of electrophysiological measurement so as to penetrate the glass electrode 102 into the Xenopus Oocyte 601, hold the membrane potential and automatically administer the medicine.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: March 25, 2003
    Assignee: Hitachi, Ltd.
    Inventors: Hirokazu Kato, Jun Otomo, Sayuri Nomura, Tomoko Takeshita, Sakae Saito, Shokichi Matsunami, Noboru Moriya
  • Publication number: 20030028908
    Abstract: An apparatus for microinjection of samples into amphibian oocytes incorporates a tray for holding a plurality of the amphibian oocytes, an injection needle for injecting a sample into the amphibian oocytes, a driving means for moving a relative position between the tray and the injection needle and a controlling device for controlling the movement by inputting a depth of the injection needle for the tray or the amphibian oocytes in the injection of the sample, and injecting the sample into the amphibian oocytes at the given depth. According to the present invention, the sample can be injected into the amphibian oocyte with constant depth precisely , and quality of the oocytes and the positional site of needle injection can be recorded as information.
    Type: Application
    Filed: October 7, 2002
    Publication date: February 6, 2003
    Applicant: Hitachi, Ltd.
    Inventors: Tomoko Takeshita, Jun Otomo, Sayuri Nomura, Shokichi Matsunami, Noboru Moriya, Sakae Saito
  • Publication number: 20030008384
    Abstract: A method or an apparatus for selecting oocytes or eggs based on at least one objective criterion, such as membrane potential, comprises a step or means for selecting a plurality of oocytes or eggs having a certain size with a filter or the like, and a step or means for measuring a membrane potential of each of the oocytes or eggs thereby sorting out those with a membrane potential within a specified range. The selected oocytes or eggs are sold or transferred together with the measurement information or an injected sample of interest.
    Type: Application
    Filed: May 15, 2002
    Publication date: January 9, 2003
    Applicant: Hitachi, Ltd.
    Inventors: Tomoko Takeshita, Jun Otomo, Shokichi Matsunami
  • Patent number: 6468784
    Abstract: A method or an apparatus for selecting oocytes or eggs based on at least one objective criterion, such as membrane potential, comprises a step or means for selecting a plurality of oocytes or eggs having a certain size with a filter or the like, and a step or means for measuring a membrane potential of each of the oocytes or eggs thereby sorting out those with a membrane potential within a specified range. The selected oocytes or eggs are sold or transferred together with the measurement information or an injected sample of interest.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: October 22, 2002
    Assignee: Hitachi, Ltd.
    Inventors: Tomoko Takeshita, Jun Otomo, Shokichi Matsunami
  • Patent number: 6470201
    Abstract: An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided. A glass electrode 103 in the air is moved toward a Xenopus Oocyte 601 held in a cell. Changes in the potential states of the glass electrodes are picked up by a control computer to distinguish the relative positions of the glass electrode 102 and the Xenopus Oocyte 601 and the sequence of electrophysiological measurement so as to penetrate the glass electrode 102 into the Xenopus Oocyte 601, hold the membrane potential and automatically administer the medicine.
    Type: Grant
    Filed: March 6, 2001
    Date of Patent: October 22, 2002
    Assignee: Hitachi, Ltd.
    Inventors: Hirokazu Kato, Jun Otomo, Sayuri Nomura, Tomoko Takeshita, Sakae Saito, Shokichi Matsunami, Noboru Moriya
  • Publication number: 20010011154
    Abstract: An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided.
    Type: Application
    Filed: March 6, 2001
    Publication date: August 2, 2001
    Applicant: Hitachi, Ltd.
    Inventors: Hirokazu Kato, Jun Otomo, Sayuri Nomura, Tomoko Takeshita, Sakae Saito, shokichi Matsunami, Noboru Moriya
  • Publication number: 20010005774
    Abstract: An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided.
    Type: Application
    Filed: December 21, 2000
    Publication date: June 28, 2001
    Inventors: Hirokazu Kato, Jun Otomo, Sayuri Nomura, Tomoko Takeshita, Sakae Saito, Shokichi Matsunami, Noboru Moriya
  • Patent number: 5976338
    Abstract: Arranging a pair of temperature control units on both sides of gel 1 and arranging light-transmitting slit 134 on one of the elements, irradiation of an excitation beam over the gel 1 and signal detection are practiced through the slit 134. Introducing dry air onto the slit part, mildew occurrence is prevented on the detecting part. Detecting the power level applied to the gel and calculating the temperature of the temperature control units so that the gel temperature might be a predetermined temperature, on the basis of the detected power level, thereafter carrying out the feedback control of the power level, the gel temperature can be controlled appropriately and strictly during electrophoresis in an automatic fluorescent electrophoresis system, so that high-speed analysis can be done highly reproducibly at a higher voltage applied even by SSCP.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: November 2, 1999
    Assignees: Hitachi, Ltd., Hitachi Electronics Engineering Co., Ltd.
    Inventors: Takeshi Fujita, Masaharu Kiyama, Shin-ichiro Umemura, Takamichi Muramatsu, Yuusuke Miyazaki, Masao Kamahori, Noboru Moriya, Shokichi Matsunami