Patents by Inventor Shomir Ghosh

Shomir Ghosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY
    Publication number: 20190119203
    Abstract: In one aspect, compounds of Formulae (I) and (II), or pharmaceutically acceptable salts thereof, are featured: Formulae (I) and (II), wherein the variables shown in Formulae (I) and (II) can be as defined anywhere herein.
    Type: Application
    Filed: April 18, 2017
    Publication date: April 25, 2019
    Inventors: Gary Glick, Shomir Ghosh, William R. Roush
  • NLRP3 MODULATORS
    Publication number: 20190055236
    Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that modulate (e.g., agonizes or partially agonizes) NLRP3 that are useful, e.g., for treating a condition, disease or disorder in which an increase in NLRP3 signaling may correct a deficiency in innate immune activity (e.g., a condition, disease or disorder associated with an insufficient immune response) that contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions as well as other methods of using and making the same.
    Type: Application
    Filed: February 16, 2018
    Publication date: February 21, 2019
    Inventors: Gary Glick, Shomir Ghosh, William R. Roush, Edward James Olhava, Daniel O'Malley
  • PESTICIDAL COMPOSITIONS AND USES THEREOF
    Publication number: 20190040078
    Abstract: Provided herein are compounds that exhibit activity as fungicides and are useful, for example, in methods for the control of fungal pathogens in plants and can be applied to said plants in a variety of ways.
    Type: Application
    Filed: July 9, 2018
    Publication date: February 7, 2019
    Inventors: Jennifer Lynn Bennett, Karen C. Fitzsimmons, Shomir Ghosh, Jeremy Robert Greenwood, William P. Haakenson, JR., Geraldine C. Harriman, Silvana Marcel Leit De Moradei, Barry J. Shortt, Urszula J. Slomczynska, Jeffrey Michael Stein
  • CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER
    Publication number: 20190031708
    Abstract: This disclosure features dinucleotide compounds that modulate Stimulator of Interferon Genes (STING) activity, for use for example in the treatment of cancer. This disclosure also features compositions as well as other methods of using and making the same.
    Type: Application
    Filed: January 11, 2017
    Publication date: January 31, 2019
    Inventors: Gary Glick, Shomir Ghosh, Edward James Olhava, William R. Roush, Roger Jones
  • CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER
    Publication number: 20190016750
    Abstract: This disclosure features dinucleotide compounds that modulate Stimulator of Interferon Genes (STING) activity, for use for example in the treatment of cancer. This disclosure also features compositions as well as other methods of using and making the same (Formula (A)). A and B are each independently selected from the group consisting of Formulae (i), (ii), (iii), and (iv).
    Type: Application
    Filed: January 11, 2017
    Publication date: January 17, 2019
    Applicant: Innate Tumoir Immunity, Inc.
    Inventors: Gary Glick, Shomir Ghosh, Edward James Olhava, William R. Roush, Roger Jones
  • ACC inhibitors and uses thereof
    Patent number: 10179793
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: January 15, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Jeremy Robert Greenwood
  • HCV protease inhibitors and uses thereof
    Patent number: 9694086
    Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: July 4, 2017
    Assignee: Celgene CAR LLC
    Inventors: Russell C. Petter, Juswinder Singh, Arthur F. Kluge, Deqiang Niu, Lixin Qiao, Shomir Ghosh
  • Protein Kinase Conjugates and Inhibitors
    Publication number: 20170174691
    Abstract: The invention relates to protein conjugates that contain a protein kinase containing a cysteine residue in the ATP binding site and an inhibitor that is covalently and irreversibly bonded to said cysteine residue, such that the activity of the protein kinase is irreversibly inhibited. The invention also relates to compounds that irreversibly inhibit protein kinases.
    Type: Application
    Filed: July 18, 2016
    Publication date: June 22, 2017
    Inventors: Juswinder Singh, Russell Colyn Petter, Deqiang Niu, Lixin Qiao, Arthur Kluge, Roy Lobb, Shomir Ghosh, Zhendong Zhu
  • TRIAZOLE ACC INHIBITORS AND USES THEREOF
    Publication number: 20170166584
    Abstract: The present invention provides triazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 22, 2016
    Publication date: June 15, 2017
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • PESTICIDAL COMPOSITIONS AND USES THEREOF
    Publication number: 20170166585
    Abstract: Provided herein are compounds that exhibit activity as fungicides and are useful, for example, in methods for the control of fungal pathogens in plants and can be applied to said plants in a variety of ways.
    Type: Application
    Filed: November 22, 2016
    Publication date: June 15, 2017
    Inventors: Jennifer Lynn Bennett, Karen C. Fitzsimmons, Shomir Ghosh, Jeremy Robert Greenwood, William P. Haakenson, JR., Geraldine C. Harriman, Silvana Marcel Leit De Moradei, Barry J. Shortt, Urszula J. Slomczynska, Jeffrey Michael Stein
  • PYRAZOLE ACC INHIBITORS AND USES THEREOF
    Publication number: 20170166582
    Abstract: The present invention provides pyrazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 22, 2016
    Publication date: June 15, 2017
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei
  • ESTER ACC INHIBITORS AND USES THEREOF
    Publication number: 20170166583
    Abstract: The present invention provides ester compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 22, 2016
    Publication date: June 15, 2017
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei
  • Chemokine receptor antagonists and methods of use
    Patent number: 9663537
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: or physiologically acceptable salt thereof.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: May 30, 2017
    Assignees: Millennium Pharmaceuticals, Inc., Kyowa Hakko Kirin Co., Ltd.
    Inventors: Jay R. Luly, Yoshisuke Nakasato, Etsuo Ohshima, Geraldine C. B. Harriman, Kenneth G. Carson, Shomir Ghosh, Amy M. Elder, Karen M. Mattia
  • ACC INHIBITORS AND USES THEREOF
    Publication number: 20170145028
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: October 26, 2016
    Publication date: May 25, 2017
    Applicant: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Geraldine C. Harriman
  • Protein kinase conjugates and inhibitors
    Patent number: 9556426
    Abstract: The invention relates to protein conjugates that contain a protein kinase containing a cysteine residue in the ATP binding site and an inhibitor that is covalently and irreversibly bonded to said cysteine residue, such that the activity of the protein kinase is irreversibly inhibited. The invention also relates to compounds that irreversibly inhibit protein kinases.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: January 31, 2017
    Assignee: Celgene Avilomics Research, Inc.
    Inventors: Juswinder Singh, Russell Colyn Petter, Deqiang Niu, Lixin Qiao, Arthur Kluge, Roy Lobb, Shomir Ghosh, Zhendong Zhu
  • HETEROARYL COMPOUNDS AND USES THEREOF
    Publication number: 20160311780
    Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
    Type: Application
    Filed: July 12, 2016
    Publication date: October 27, 2016
    Inventors: Juswinder Singh, Shomir Ghosh, Arthur F. Kluge, Russell C. Petter, Richland Wayne Tester
  • HETEROARYL COMPOUNDS AND USES THEREOF
    Publication number: 20160279127
    Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
    Type: Application
    Filed: March 7, 2016
    Publication date: September 29, 2016
    Inventors: Juswinder Singh, Shomir Ghosh, Arthur F. Kluge, Russell C. Petter, Richland W. Tester
  • HCV PROTEASE INHIBITORS AND USES THEREOF
    Publication number: 20160243249
    Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
    Type: Application
    Filed: September 15, 2015
    Publication date: August 25, 2016
    Inventors: Russell C. Petter, Juswinder Singh, Arthur F. Kluge, Deqiang Niu, Lixin Qiao, Shomir Ghosh
  • HCV PROTEASE INHIBITORS AND USES THEREOF
    Publication number: 20160235805
    Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
    Type: Application
    Filed: October 19, 2015
    Publication date: August 18, 2016
    Inventors: Russell C. Petter, Juswinder Singh, Arthur F. Kluge, Deqiang Niu, Lixin Qiao, Shomir Ghosh
  • 4,6-disubstituted pyrimidines as kinase inhibitors
    Patent number: 9393246
    Abstract: The present invention provides 4,6-disubstituted pyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods of using the same.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: July 19, 2016
    Assignee: Celgene Avilomics Research, Inc.
    Inventors: Juswinder Singh, Shomir Ghosh, Arthur Kluge, Russell C. Petter, Richland W. Tester