Patents by Inventor Shoshanna TESSLER

Shoshanna TESSLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE FORM OF ASPACYTARABINE
    Publication number: 20230331762
    Abstract: The present invention relates to a novel crystalline polymorph of (¾)-2-amino-4-(0-42R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyptetrahydrofuran-2-yl)-2-oxo-1,2- dihydropyrimidin-4-yl)amino)-4-oxobutanoic acid (also known as BST-236, Astarabine® or aspacytarabine), processes of preparation thereof, and uses thereof for the treatment of neoplastic diseases.
    Type: Application
    Filed: September 20, 2021
    Publication date: October 19, 2023
    Applicant: Biosight Ltd.
    Inventors: Ramy LIDOR-HADAS, Margarita SHUMILOV, Shoshanna TESSLER
  • ASPACYTARABINE PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
    Publication number: 20230090683
    Abstract: The present invention relates to a composition comprising aspacytarabine (also known as BST-236 and Astarabine®) or a pharmaceutically acceptable salt thereof and an stabilizer and/or solubilizer, wherein the stabilizer and/or solubilizer is selected from at least one water soluble stabilizer and/or solubilizer such as a linear polymer or derivative thereof, an inclusion compound (i.e. cyclodextrin) and combination thereof. The present invention further relates to uses of the composition, particularly for use in the treatment of neoplastic disease.
    Type: Application
    Filed: February 4, 2021
    Publication date: March 23, 2023
    Applicant: Biosight Ltd.
    Inventors: Margarita SHUMILOV, Shoshanna TESSLER