Patents by Inventor Shouichi TATEYAMA

Shouichi TATEYAMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing optically active 5-hydroxy-3-ketoester
    Patent number: 9701642
    Abstract: The object of the present invention is to provide a method for producing in high yield with high stereoselectivity an optically active 5-hydroxy-3-ketoester compound which is useful as an intermediate for a pharmaceutical. A novel method for producing an optically active 5-hydroxy-3-ketoester compound in which an asymmetric aldol reaction by use of 1,3-diene compound is carried out in the presence of an optically active binaphthol-titanium complex together with a substituted nitrogen-containing 5 or 6-membered aromatic heterocyclic compound to obtain an optically active 5-hydroxy-3-ketoester compound in high yield with high stereoselectivity; and a novel production intermediate having a crystalline form.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: July 11, 2017
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Shouichi Tateyama, Shinya Naitou, Yasutaka Takada, Mariko Ishida, Hirohide Kitsuyama
  • METHOD FOR PRODUCING OPTICALLY ACTIVE 5-HYDROXY-3-KETOESTER
    Publication number: 20160185734
    Abstract: The object of the present invention is to provide a method for producing in high yield with high stereoselectivity an optically active 5-hydroxy-3-ketoester compound which is useful as an intermediate for a pharmaceutical. A novel method for producing an optically active 5-hydroxy-3-ketoester compound in which an asymmetric aldol reaction by use of 1,3-diene compound is carried out in the presence of an optically active binaphthol-titanium complex together with a substituted nitrogen-containing 5 or 6-membered aromatic heterocyclic compound to obtain an optically active 5-hydroxy-3-ketoester compound in high yield with high stereoselectivity; and a novel production intermediate having a crystalline form.
    Type: Application
    Filed: August 26, 2014
    Publication date: June 30, 2016
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Shouichi TATEYAMA, Shinya NAITOU, Yasutaka TAKADA, Mariko ISHIDA, Hirohide KITSUYAMA