Patents by Inventor Shouming ZHAO

Shouming ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of (?)-huperzine A
    Patent number: 9586904
    Abstract: The present invention relates to a method for preparing (?)-huperzine A. The method involves: allowing a mixture of (±)-huperzine A obtained from chemical synthesis and a chiral acid to form (±)-huperzine A chiral acid salt under suitable conditions; recrystallizing the chiral acid salt from an organic solvent and basifying with an alkali to obtain optically pure (?)-huperzine A. The method is convenient to operate and suitable for industrial production. The chemical purity and optical purity of (?)-huperzine A obtained by the method are each greater than 99.5%, satisfying the requirement for raw pharmaceutical purity in the pharmaceutical industry.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: March 7, 2017
    Assignee: ZHEJIANG WANBANG PHARMACEUTICAL PLC.
    Inventors: Shouming Zhao, Ping Chen, Shaoping Peng, Yinqiang Zhuang, Rongzhen Shi, Jinsheng Xie, Weihua Xie
  • PREPARATION OF (-)-HUPERZINE A
    Publication number: 20160159745
    Abstract: The present invention relates to a method for preparing (?)-huperzine A. The method involves: allowing a mixture of (±)-huperzine A obtained from chemical synthesis and a chiral acid to form (±)-huperzine A chiral acid salt under suitable conditions; recrystallizing the chiral acid salt from an organic solvent and basifying with an alkali to obtain optically pure (?)-huperzine A. The method is convenient to operate and suitable for industrial production. The chemical purity and optical purity of (?)-huperzine A obtained by the method are each greater than 99.5%, satisfying the requirement for raw pharmaceutical purity in the pharmaceutical industry.
    Type: Application
    Filed: June 17, 2014
    Publication date: June 9, 2016
    Inventors: Shouming ZHAO, Ping CHEN, Shaoping PENG, Yinqiang ZHUANG, Rongzhen SHI, Jinsheng XIE, Weihua XIE
  • Distribution station
    Patent number: D948075
    Type: Grant
    Filed: August 5, 2020
    Date of Patent: April 5, 2022
    Inventors: Chunyang Sun, Jian Li, Shouming Zhao, Yue Yang