Patents by Inventor Shozo Koyama

Shozo Koyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7914793
    Abstract: This invention provides antigen substance inductors which produce highly selective and/or specific vaccine precursor, vaccine, antibody (including idiotype antibody), neutralizing antibody, antitoxin. This invention is to produce and/or manufacture highly selective and/or specific vaccine precursor, vaccine, antibody (including idiotype antibody), neutralizing antibody, antitoxin by quantum thermodynamic and chemical control of molecular functions and morphogenesis, inducing non-functional complex macromolecules which form organism and/or non-organism and which become to be substance with fundamental structure more closed to an induction of the functions, utilizing the fundamental structure of molecule which is indicated in Formula 3-a as a representative molecule. Moreover, by those produced substances, this invention is to produce and/or manufacture antimicrobial agent, antiviral agent, neutralizing antibody, antitoxin, antitumor agent, anti-protozoa agent (malaria, spirochaeta et.
    Type: Grant
    Filed: February 26, 2004
    Date of Patent: March 29, 2011
    Inventors: Shozo Koyama, Satoshi Tanaka
  • Patent number: 7605183
    Abstract: A method for inhibiting or blocking molecular generating and/or inducing functions of molecules using an inhibitory or blocking agent of the formula: wherein R1-6 are as defined herein.
    Type: Grant
    Filed: August 9, 2007
    Date of Patent: October 20, 2009
    Inventors: Shozo Koyama, Yoshihiro Yamaguchi
  • Publication number: 20090216117
    Abstract: A drug in the form of a solid preparation soluble or suspendable in water or an aqueous solution characterized by containing at least one biocompatible, gastric motility suppressing component such as triacetin, which is capable of transmitting ultrasonic wave to a target organ via the solution pooled in the body in a noninvasive examination (for example, an ultrasonic examination of an abdominal organ), identifying the area in which the solution exists, or clarifying the boundary of the solution and an organ in contact therewith, is employed as an auxiliary agent in the examination. In addition, triacetin can be extensively used as a gastric motility suppressor.
    Type: Application
    Filed: April 17, 2006
    Publication date: August 27, 2009
    Applicants: SHINSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY, FUSHIMI PHARMACEUTICAL CO., LTD.
    Inventors: Shozo Koyama, Masaaki Tokuda, Yoshiyuki Hori, Kazumasa Ohsaka
  • Publication number: 20080200558
    Abstract: A method for inhibiting or blocking molecular generating and/or inducing functions of molecules using an inhibitory or blocking agent of the formula: wherein R1-6 are as defined herein.
    Type: Application
    Filed: August 9, 2007
    Publication date: August 21, 2008
    Inventors: Shozo Koyama, Yoshihiro Yamaguchi
  • Publication number: 20070293848
    Abstract: The present invention provides a medical instrument with use of a composite material, which has antithrombotic characteristics and biocompatibility, has a favorable strength per se and is excellent in handling properties. A part or the whole of a section of the medical instrument, which is brought into contact with blood, is made of or coated with the composite material, which has antithrombotic characteristics and in which carbon nanotubes are blended with matrix resin.
    Type: Application
    Filed: December 6, 2005
    Publication date: December 20, 2007
    Inventors: Morinobu Endo, Shozo Koyama, Masao Ichinose
  • Publication number: 20070066654
    Abstract: A method for inhibiting or blocking molecular generating and/or inducing functions of molecules using an inhibitory or blocking agent of the formula: wherein R1-6 are as defined herein.
    Type: Application
    Filed: August 31, 2006
    Publication date: March 22, 2007
    Inventors: Shozo Koyama, Yoshihiro Yamaguchi
  • Publication number: 20040230067
    Abstract: This invention provides antigen substance inductors which produce highly selective and/or specific vaccine precursor, vaccine, antibody (including idiotype antibody), neutralizing antibody, antitoxin.
    Type: Application
    Filed: February 26, 2004
    Publication date: November 18, 2004
    Inventors: Shozo Koyama, Satoshi Tanaka
  • Publication number: 20040224926
    Abstract: A method for inhibiting or blocking molecular generating and/or inducing functions of molecules using an inhibitory or blocking agent of the formula: 1
    Type: Application
    Filed: November 24, 2003
    Publication date: November 11, 2004
    Inventors: Shozo Koyama, Yoshihiro Yamaguchi
  • Patent number: 6710090
    Abstract: A method for inhibiting or blocking molecular generating and/or inducing functions of molecules using an inhibitory or blocking agent of the formula: wherein R1-6 and A are as defined herein.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: March 23, 2004
    Inventors: Shozo Koyama, Yoshihiro Yamaguchi
  • Publication number: 20020165206
    Abstract: The invention is concerned in the compounds, the derivatives or those acid addition salt compounds which has the original molecular structure shown in general formula (1-a) with the following effective ingredients; antibacterial agents, antifungal agents, antiviral agents, bactericidal and/or sterilized agents, anticancer agents, blood coagulation and fibrinolysis inhibitors and/or blocking agents, inhibitory and/or blocking agents of antigen-antibody reaction, organ and/or tissue preservatives, antiseptics and preservatives for foodstuffs, spermatocidal agents and/or contraceptive agents of external use, thrombolytic agents, conformation altering agents of saccharide-chains, agents for preventing arteriosclerosis, metabolism (proteins, lipids, sugar) improving agents, promoting agents for wound healing, epithelialization promoting agents, inhibitors and/or blocking agents which can control generation of function with bioactive substances (for example, enzymes, peptides, gene), depolymerization agents, improv
    Type: Application
    Filed: December 28, 2001
    Publication date: November 7, 2002
    Inventors: Shozo Koyama, Yoshihiro Yamaguchi
  • Publication number: 20020009467
    Abstract: This invention provides antigen substance inductors which produce highly selective and/or specific vaccine precursor, vaccine, antibody (including idiotype antibody), neutralizing antibody, antitoxin.
    Type: Application
    Filed: June 18, 2001
    Publication date: January 24, 2002
    Inventors: Shozo Koyama, Satoshi Tanaka
  • Patent number: 4388318
    Abstract: The method of treating endotoxin shock with 2,2'-[(4,8-bis(diethylamino)-pyrimido[5,4-d]pyrimidine-2,6-diyl)di-(2-meth oxyethyl)imino]diethanol or a non-toxic, pharmacologically acceptable acid addition salt thereof.
    Type: Grant
    Filed: September 29, 1981
    Date of Patent: June 14, 1983
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Shozo Koyama, John W. Manning, Jr., William S. Ammons, Hector L. Santiesteban