Patents by Inventor Shreedharan Sriram
Shreedharan Sriram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11560570Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmTEFs1 gene. Some embodiments relate to a promoter or a 5? UTR from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: GrantFiled: November 30, 2021Date of Patent: January 24, 2023Assignee: CORTEVA AGRISCIENCE LLCInventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler
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Patent number: 11492631Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmPSID2 gene. Some embodiments relate to a promoter or a 5? UTR from a GmPSID2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmPSID2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: GrantFiled: October 31, 2018Date of Patent: November 8, 2022Assignee: CORTEVA AGRISCIENCE LLCInventors: Lyudmila Sidorenko, Cory Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler
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Patent number: 11473095Abstract: This disclosure concerns the use of endogenous plant RNAi machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in seed tissues of a dicot plant.Type: GrantFiled: April 23, 2020Date of Patent: October 18, 2022Assignee: CORTEVA AGRISCIENCE LLCInventors: Sandeep Kumar, Marcelo Ariel German, Po-Hao Wang, Todd P. Glancy, Shreedharan Sriram, Carla N. Yerkes, Andrew J. Bowling, Heather Pence, Andrew E. Robinson
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Publication number: 20220162624Abstract: As disclosed herein, optimal native genomic loci from maize plants have been identified that represent best sites for targeted insertion of exogenous sequences.Type: ApplicationFiled: October 13, 2021Publication date: May 26, 2022Applicant: CORTEVA AGRISCIENCE LLCInventors: Lakshmi SASTRY-DENT, Zehui CAO, Shreedharan SRIRAM, Steven R. WEBB, Debra L. CAMPER
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Publication number: 20220090109Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmTEFs1 gene. Some embodiments relate to a promoter or a 5? UTR from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: ApplicationFiled: November 30, 2021Publication date: March 24, 2022Applicant: Corteva Agriscience LLCInventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler
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Publication number: 20220090111Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmCAB2 gene. Some embodiments relate to a promoter or a 5? UTR from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: ApplicationFiled: November 30, 2021Publication date: March 24, 2022Applicants: CORTEVA AGRISCIENCE LLC, PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler, Lynne E. Sims, Scott H. Diehn, Gilda M. Rauscher, Kevin G. Ripp, Knut Meyer
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Patent number: 11274311Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmTEFs1 gene. Some embodiments relate to a promoter or a 5? UTR from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: GrantFiled: October 31, 2018Date of Patent: March 15, 2022Assignee: Corteva Agriscience LLCInventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler
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Patent number: 11225670Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmCAB2 gene. Some embodiments relate to a promoter or a 5? UTR from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: GrantFiled: October 29, 2018Date of Patent: January 18, 2022Assignees: Corteva Agriscience LLC, Pioneer Hi-Bred International, Inc.Inventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler, Lynne E. Sims, Scott H. Diehn, Gilda M. Rauscher, Kevin G. Ripp, Knut Meyer
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Patent number: 11198882Abstract: As disclosed herein, optimal native genomic loci from maize plants have been identified that represent best sites for targeted insertion of exogenous sequences.Type: GrantFiled: August 24, 2018Date of Patent: December 14, 2021Inventors: Lakshmi Sastry-Dent, Zehui Cao, Shreedharan Sriram, Steven R. Webb, Debra L. Camper
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Patent number: 11149287Abstract: As disclosed herein, optimal native genomic loci have been identified in dicot plants, such as soybean plants, that represent best sites for targeted insertion of exogenous sequences.Type: GrantFiled: January 14, 2019Date of Patent: October 19, 2021Assignee: Corteva Agriscience LLCInventors: Lakshmi Sastry-Dent, Zehui Cao, Shreedharan Sriram, Steven R. Webb, Debra L. Camper
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Patent number: 11098317Abstract: As disclosed herein, optimal native genomic loci have been identified in monocot plants, such as maize plants, that represent best sites for targeted insertion of exogenous sequences.Type: GrantFiled: January 31, 2019Date of Patent: August 24, 2021Assignee: Corteva Agriscience LLCInventors: Lakshmi Sastry-Dent, Zehui Cao, Shreedharan Sriram, Steven R. Webb, Debra L. Camper, Navin Elango
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Patent number: 11098316Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.Type: GrantFiled: September 6, 2018Date of Patent: August 24, 2021Assignee: Corteva Agriscience LLCInventors: Lakshmi Sastry-Dent, Zehui Cao, Shreedharan Sriram, Steven R. Webb, Debra L. Camper, W. Michael Ainley
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Publication number: 20210230617Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.Type: ApplicationFiled: April 7, 2021Publication date: July 29, 2021Inventors: Lakshmi SASTRY-DENT, Zehui CAO, Shreedharan SRIRAM, Steven R. WEBB, Debra L. CAMPER, W. Michael AINLEY
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Publication number: 20200392524Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmPSID2 gene. Some embodiments relate to a promoter or a 5? UTR from a GmPSID2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmPSID2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: ApplicationFiled: October 31, 2018Publication date: December 17, 2020Applicant: Dow AgroSciences LLCInventors: Lyudmila Sidorenko, Cory Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler
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Publication number: 20200347395Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmCAB2 gene. Some embodiments relate to a promoter or a 5? UTR from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: ApplicationFiled: October 29, 2018Publication date: November 5, 2020Applicants: DOW AGROSCIENCES LLC, PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler, Lynne E. Sims, Scott H. Diehn, Gilda M. Rauscher, Kevin G. Ripp, Knut Meyer
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Publication number: 20200318127Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmTEFs1 gene. Some embodiments relate to a promoter or a 5? UTR from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3? UTR or a terminator from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences.Type: ApplicationFiled: October 31, 2018Publication date: October 8, 2020Applicant: Dow AgroSciences LLCInventors: Lyudmila Sidorenko, Cory M. Larsen, Geny Anthony, Shreedharan Sriram, Holly Jean Butler
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Publication number: 20200248197Abstract: This disclosure concerns the use of endogenous plant RNAi machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in seed tissues of a dicot plant.Type: ApplicationFiled: April 23, 2020Publication date: August 6, 2020Applicant: Dow AgroSciences LLCInventors: Sandeep Kumar, Marcelo Ariel German, Pahao Wang, Todd P. Glancy, Shreedharan Sriram, Carla N. Yerkes, Andrew J. Bowling, Heather Pence, Andrew E. Robinson
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Publication number: 20200224269Abstract: The present invention is based on the use of the H3K9me2 methylation levels in plant genomes to predict transgene silencing, transgene stability, and/or transgene expression level. Provided are methods and/or systems for generating whole-genome H3K9me2 maps and its use with an assigned threshold value for predicting gene silencing. The methods and/or systems provided herein can be used in high-throughput setting for screening large number of transformed event in a relatively short period of time as compared to existing technologies.Type: ApplicationFiled: March 16, 2020Publication date: July 16, 2020Applicant: Dow AgroSciences LLCInventors: PoHao Wang, Shreedharan Sriram, Lakshmi Sastry-Dent
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Patent number: 10633703Abstract: The present invention is based on the use of the H3K9me2 methylation levels in plant genomes to predict transgene silencing, transgene stability, and/or transgene expression level. Provided are methods and/or systems for generating whole-genome H3K9me2 maps and its use with an assigned threshold value for predicting gene silencing. The methods and/or systems provided herein can be used in high-throughput setting for screening large number of transformed event in a relatively short period of time as compared to existing technologies.Type: GrantFiled: October 25, 2016Date of Patent: April 28, 2020Assignee: Dow AgroSciences LLCInventors: Pohao Wang, Shreedharan Sriram, Lakshmi Sastry-Dent
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Publication number: 20190194674Abstract: As disclosed herein, optimal native genomic loci have been identified in monocot plants, such as maize plants, that represent best sites for targeted insertion of exogenous sequences.Type: ApplicationFiled: January 31, 2019Publication date: June 27, 2019Inventors: Lakshmi SASTRY-DENT, Zehui CAO, Shreedharan SRIRAM, Steven R. WEBB, Debra L. CAMPER, Navin ELANGO
