Patents by Inventor Shreeram N. Agharkar

Shreeram N. Agharkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10463707
    Abstract: The present invention relates to a process for preparing pharmaceutical compositions and other herbal products derived from herbs of Traditional Chinese Medicine (TCM), including Radix astragali (Milkvetch—Huang Qi), Ligusticum chuanxiong (Chuan Xiong), Radix angelicae sinensis (Chinese Angelica—Dang Gui) and Radix polygalae (Thinleaf milkwort—Yuan Zhi). The process includes a single extraction of the TCM herbs by heating in a hydro-alcoholic solvent, wherein the alcohol may be ethanol. FIG. 2 provides an overview of one embodiment of the process. The invention also relates to products of the process of the invention, and their use in the treatment of stroke and various neurological disorders.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: November 5, 2019
    Assignee: MOLEAC PTE LTD.
    Inventors: Kirti S Laddha, Shreeram N. Agharkar
  • Publication number: 20180264062
    Abstract: The present invention relates to a process for preparing pharmaceutical compositions and other herbal products derived from herbs of Traditional Chinese Medicine (TCM), including Radix astragali (Milkvetch—Huang Qi), Ligusticum chuanxiong (Chuan Xiong), Radix angelicae sinensis (Chinese Angelica—Dang Gui) and Radix polygalae (Thinleaf milkwort—Yuan Zhi). The process includes a single extraction of the TCM herbs by heating in a hydro-alcoholic solvent, wherein the alcohol may be ethanol. FIG. 2 provides an overview of one embodiment of the process. The invention also relates to products of the process of the invention, and their use in the treatment of stroke and various neurological disorders.
    Type: Application
    Filed: September 13, 2016
    Publication date: September 20, 2018
    Inventors: Kirti S LADDHA, Shreeram N. AGHARKAR
  • Patent number: 5703111
    Abstract: This invention relates to a stable, easy to constitute, injectable formulation of anticancer agent BMY-25067. More specifically, the present invention concerns a formulation of BMY-25067 obtained from lyophilizing a solution comprising up to 4 mg of BMY-25067 per mL of 65% t-butanol/water, further comprising about 2% PVP (K-12 or K-17), optionally comprising pharmaceutically acceptable carrier(s).
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: December 30, 1997
    Assignee: Bristol-Myers Squibb Company
    Inventors: Uday S. Gogate, Shreeram N. Agharkar, Lawan Phusanti
  • Patent number: 5504102
    Abstract: A stabilized pharmaceutical composition containing paclitaxel, teniposide, camptothecin or other antineoplastic agent susceptible to degradation during storage is produced using a solvent system containing a low carboxylate anion content. The solvent system is a mixture of ethanol and a polyoxyethylated castor oil. The polyoxyethylated castor oil is treated with an acid or contacted with alumina to reduce the carboxylate anion content of the solvent. The low carboxylate anion content of the solvent provides extended shelf life and lower amounts of degradation by-products.
    Type: Grant
    Filed: January 18, 1995
    Date of Patent: April 2, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Shreeram N. Agharkar, Uday S. Gogate
  • Patent number: 5216011
    Abstract: A stable solution of mitomycin C in propylene glycol or propylene glycol/water is disclosed. The solutions have an acceptable shelf-life of greater than 24 months at 4.degree. C. and can be injected directly or diluted with water or other aqueous parenteral vehicle for parenteral administration.
    Type: Grant
    Filed: September 1, 1989
    Date of Patent: June 1, 1993
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Mehdi Paborji, Joseph B. Bogardus, Shreeram N. Agharkar, William P. Coppola
  • Patent number: 4927638
    Abstract: A solution of etoposide in dimethylisosorbide is disclosed. The solution is useful for filling gelatin capsules and may also be formulated into parenteral dosage forms.
    Type: Grant
    Filed: September 12, 1988
    Date of Patent: May 22, 1990
    Assignee: Bristol-Myers Company
    Inventors: Gururaj Bykadi, Murray A. Kaplan, Richard G. Corrao, Edward J. Bara, Ismat Ullah, Shreeram N. Agharkar
  • Patent number: 4882356
    Abstract: Stable, injectable, aqueous solutions of 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-[(substituted)alkoxy]benzamid e antiemetic agents are prepared by adding, as stabilizing agent, a pharmaceutically acceptable, water-miscible, hydroxylic organic solvent or water-soluble polyhydric alcohol or sugar which decreases the polarity of the solution.
    Type: Grant
    Filed: March 10, 1987
    Date of Patent: November 21, 1989
    Inventors: Munir N. Nassar, Shreeram N. Agharkar, Joseph B. Bogardus