Abstract: Various implementations include a competitive assay platform with a partitioning device disposed in a well. The well has a bottom surface, a central axis, and a side surface. The partitioning device includes a first wall portion, a second wall portion, and a third wall portion. Each wall portion has an upper edge, a lower edge, a first side edge, a second side edge, and first and second divider surfaces. The lower edge of the first wall portion, second wall portion, and third wall portion of the partitioning device disposed on the bottom surface of the well, and the first side edges of the first, second, and third wall portions are disposed against the side surface of the well, defining first, second, and third compartments.

Abstract: The present disclosure relates generally to techniques for capturing cancer cells and, more particularly, to techniques for capturing metastatic cancer cells in vivo.

Abstract: Pharmaceutical compositions and methods of inhibiting tumor cell proliferation of triple-negative (ER?/PR?/HER2?) breast cancer cells and for treating subjects with a form of breast cancer having a triple-negative (ER?/PR?/HER2?) phenotype are provided. The methods include a step of contacting triple-negative breast cancer cells with an effective amount of a composition including Eribulin and CYC065.