Patents by Inventor Shridhar K. Sathe

Shridhar K. Sathe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8273856
    Abstract: Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: September 25, 2012
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Suzanne S. Teuber
  • Patent number: 8114605
    Abstract: Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: February 14, 2012
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Suzanne S. Teuber
  • Patent number: 8007770
    Abstract: A purified Ig-E binding immunogenic polypeptide the amino acid sequence of which consists of SEQ ID NO:1 is disclosed. The purified amino acid sequence is a major allergen of the walnut Juglans regia. Also described are a diagnostic test kit and use of the purified polypeptide in tests for identifying patients having an allergy to walnuts. Mutations of the disclosed polypeptide, as well as nucleic acid sequences encoding therefor are claimed as part of the invention.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: August 30, 2011
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Jason M. Robotham, Suzanne S. Teuber
  • Publication number: 20100311603
    Abstract: Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
    Type: Application
    Filed: May 15, 2009
    Publication date: December 9, 2010
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Suzanne S. Teuber
  • Patent number: 7763721
    Abstract: A purified Ig-E binding immunogenic polypeptide the amino acid sequence of which consists of SEQ ID NO:1 is disclosed. The purified amino acid sequence is a major allergen of the walnut Juglans regia. Also described are a diagnostic test kit and use of the purified polypeptide in tests for identifying patients having an allergy to walnuts. Mutations of the disclosed polypeptide, as well as nucleic acid sequences encoding therefor are claimed as part of the invention.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: July 27, 2010
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Kenneth Roux, Suzanne Teuber, Shridhar K. Sathe, Jason Robotham
  • Patent number: 7763709
    Abstract: The invention describes an isolated nucleic acid sequence comprising the nucleotide sequence of SEQ ID NO: 1 or a degenerate variant of SEQ ID NO:1. The nucleic acid sequence encodes an Ig-E binding immunogenic polypeptide the amino acid sequence of which comprises at least one sequence selected from SEQ ID NOS:4-25. The invention additionally provides an in vitro diagnostic test for detecting anti-cashew IgE in a patient.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: July 27, 2010
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Kenneth Roux, Suzanne Teuber, Shridhar K. Sathe, Jason Robotham
  • Patent number: 7537914
    Abstract: The invention describes an isolated nucleic acid sequence comprising the nucleotide sequence of SEQ ID NO:1 or a degenerate variant of SEQ ID NO:1. The nucleic acid sequence encodes an Ig-E binding immunogenic polypeptide the amino acid sequence of which comprises at least one sequence selected from SEQ ID NOS:4-25. The invention additionally provides an in vitro diagnostic test for detecting anti-cashew IgE in a patient. The test comprises reacting the patient's serum with a purified polypeptide the amino acid sequence of which comprises at least one sequence selected from SEQ ID NOS:3-25; separating the polypeptide from unreacted patient serum; reacting the polypeptide with a labeled human IgE-reactive agent after separating from unreacted patient serum; separating the polypeptide from unreacted labeled human IgE-reactive agent; and detecting labeled human IgE-reactive agent bound to the polypeptide after separating from unreacted agent to thereby indicate presence in the patient's serum of anti-cashew IgE.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: May 26, 2009
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Kenneth Roux, Shridhar K. Sathe, Jason M. Robotham, Suzanne S. Teuber
  • Patent number: 7538203
    Abstract: Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: May 26, 2009
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Suzanne S. Teuber
  • Publication number: 20090092959
    Abstract: The invention describes an isolated nucleic acid sequence comprising the nucleotide sequence of SEQ ID NO:1 or a degenerate variant of SEQ ID NO: 1. The nucleic acid sequence encodes an Ig-E binding immunogenic polypeptide the amino acid sequence of which comprises at least one sequence selected from SEQ ID NOS:4-25. The invention additionally provides an in vitro diagnostic test for detecting anti-cashew IgE in a patient.
    Type: Application
    Filed: October 4, 2007
    Publication date: April 9, 2009
    Inventors: Kenneth Roux, Shridhar K. Sathe, Jason M. Robotham, Suzanne S. Teuber
  • Patent number: 7381534
    Abstract: Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: June 3, 2008
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Suzanne S. Teuber
  • Patent number: 7250489
    Abstract: A purified Ig-E binding immunogenic polypeptide the amino acid sequence of which consists of SEQ ID NO:1 is disclosed. The purified amino acid sequence is a major allergen of the walnut Juglans regia. Also described are a diagnostic test kit and use of the purified polypeptide in tests for identifying patients having an allergy to walnuts. Mutations of the disclosed polypeptide, as well as nucleic acid sequences encoding therefor are claimed as part of the invention.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: July 31, 2007
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Jason M. Robotham, Suzanne S. Teuber
  • Patent number: 6884877
    Abstract: Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
    Type: Grant
    Filed: October 3, 2002
    Date of Patent: April 26, 2005
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Suzanne S. Teuber
  • Publication number: 20030124060
    Abstract: Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
    Type: Application
    Filed: October 3, 2002
    Publication date: July 3, 2003
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Suzanne S. Teuber
  • Publication number: 20030103903
    Abstract: A purified Ig-E binding immunogenic polypeptide the amino acid sequence of which consists of SEQ ID NO:1 is disclosed. The purified amino acid sequence is a major allergen of the walnut Juglans regia. Also described are a diagnostic test kit and use of the purified polypeptide in tests for identifying patients having an allergy to walnuts. Mutations of the disclosed polypeptide, as well as nucleic acid sequences encoding therefor are claimed as part of the invention.
    Type: Application
    Filed: September 20, 2002
    Publication date: June 5, 2003
    Inventors: Kenneth H. Roux, Shridhar K. Sathe, Jason M. Robotham, Suzanne Teuber