Patents by Inventor Shrikumar Suryanarayan

Shrikumar Suryanarayan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing mycophenolic acid using BICC 7673
    Patent number: 7625727
    Abstract: The present invention discloses the manufacture of MPA by fermentation under optimal fermentation parameters using a new strain of Penicillium arenicola.
    Type: Grant
    Filed: October 5, 2004
    Date of Patent: December 1, 2009
    Assignee: Biocon Limited
    Inventors: Surekha Prabhu, Pinakee Devi Sharma, Sanjay Tiwari, Ramakrishnan Melarkode, Ramavana Gururaja, Shrikumar Suryanarayan
  • Process for the Production of Macrolides Using a Novel Strain, Streptomyces Sp. Bicc 7522
    Publication number: 20080286842
    Abstract: The present invention discloses a new strain of Streptomyces sp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of microlides.
    Type: Application
    Filed: April 12, 2004
    Publication date: November 20, 2008
    Applicant: BIOCON LIMITED
    Inventors: Madhav Kulkarni, Surekha K. Prabhu, M.C. Shivakumar, Prijyajit Sengupta, Sanjay Tiwari, Rakesh Mendhe, Nitin Patil, Laxmi Adhikary, Anand Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja, Shrikumar Suryanarayan
  • Process For Producing Mycophenolic Acid Using Penicillium Arenicola Bicc 7673
    Publication number: 20080227164
    Abstract: The present invention discloses the manufacture of MPA by fermentation under optimal fermentation parameters using a new strain of Penicillium arenicola.
    Type: Application
    Filed: October 5, 2004
    Publication date: September 18, 2008
    Inventors: Surekha Prabhu, Pinakee Devi Sharma, Sanjay Tiwari, Ramakrishnan Melarkode, Ramavana Gururaja, Shrikumar Suryanarayan
  • Preparation of Insulin Conjugates
    Publication number: 20080139784
    Abstract: The present invention discloses a process for making an insulin-oligomer conjugate as a one-pot reaction by conjugation of insulin-ester with an activated oligomer wherein simultaneous deblocking and conjugation is carried out.
    Type: Application
    Filed: July 8, 2005
    Publication date: June 12, 2008
    Applicant: Biocon Limited
    Inventors: Partha Hazra, H.S. Manjunath, Anand Khedkar, Harish Iyer, Nitesh Dave, Gautam Krishnan, Shrikumar Suryanarayan
  • Process for producing pravastatin sodium salt using dsm 14455
    Patent number: 7189558
    Abstract: In one aspect, the present invention provides an improved method for the manufacture of Pravastatin sodium salt by fermentation under optimal fermentation parameters using a new strain of Streptomyces flavidovirens.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: March 13, 2007
    Assignee: Biocon Limited
    Inventors: Ramavana Gururaja, Anuj Goel, Madhavan Sridharan, Ramakrishnan Sadhana Melarkode, Madhav Kulkarni, Acharya Poornaprajna, Deepthy Sathyanathan, Sambasivam Ganesh, Shrikumar Suryanarayan
  • Manufacture and purification of cyclosporin A
    Patent number: 7176001
    Abstract: The present invention provides an improved method for the manufacture of Cyclosporin A is disclosed. Cyclosporin A is produced by solid state fermentation of Fusarium solani in a bioreactor under optimal fermentation parameters. The product is extracted and further purified by treating with alum and subsequent chromatographic procedures to get pharmaceutical acceptable purity.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: February 13, 2007
    Assignee: Biocon Limited
    Inventors: Anand Prakash Khedkar, Pampapathy Subramaniyam, Konayakanahalli Nanjunda Swamy Anand, Melarkode Ramkrishna, Shreehas Pradeep Tambe, Sambasivam Ganesh, Anindya Sircar, Shrikumar Suryanarayan
  • Manufacture and purification of mycophenolic acid
    Patent number: 6927047
    Abstract: The present invention provides an improved method for the manufacture of Mycophenolic acid by solid substrate fermentation of Pencillium brevi-campactum, in a contained bioreactor under optimal fermentation parameters with its subsequent purification steps.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: August 9, 2005
    Assignee: Biocon Limited
    Inventors: Anindya Sircar, Shrikumar Suryanarayan, Anand Prakash Khedkar, Pampapathy Subramaniyam, Shreehas Pradeep Tambe
  • Process for producing pravastatin sodium salt using streptomyces flavidovirens dsm 14455
    Publication number: 20040209335
    Abstract: In one aspect, the present invention provides an improved method for the manufacture of Pravastatin sodium salt by fermentation under optimal fermentation parameters using a new strain of Streptomyces flavidovirens.
    Type: Application
    Filed: February 4, 2004
    Publication date: October 21, 2004
    Inventors: Ramavana Gururaja, Anuj Goel, Madhavan Sridharan, Ramakrishnan Sadhana Melarkode, Madhav Kulkarni, Acharya Poornaprajna, Deepthy Sathyanathan, Sambasivam Ganesh, Shrikumar Suryanarayan
  • Methods of producing esters of mycophenolate
    Patent number: 6709846
    Abstract: Methods for the manufacture of Mycophenolate are disclosed. Mycophenblate mofetil is biochemically synthesized using Mycophenolic Acid and 2-morpholino ethanol with the help of an enzyme. Mycophenolate mofetil is also chemically synthesized non-catalytically by refluxing mycophenolic acid with 2-morpholino ethanol in the absence of a third solvent or a catalyst.
    Type: Grant
    Filed: June 7, 2001
    Date of Patent: March 23, 2004
    Assignee: Biocon India Limited
    Inventors: Anindya Sircar, Anand Khedkar, Madhay Kulkarni, Shrikumar Suryanarayan, Madhavan Sridharan, Poornaprajna Acharya, Ganesh Samvasivam, Ramakrishnan Melarkode
  • Solid state fermentation
    Patent number: 6664095
    Abstract: The present invention provides an improved solid state fermentation device that combines all of the operations of microorganism cultivation (sterilization, inoculation, cultivation, extraction, and post extraction treatment). This solid state fermentation device is modular in nature and operates in a contained manner so that the live microorganisms from the reactor cannot come into contact with the environment and pollute the environment and also so that the environment inside the bioreactor is aseptic. Another aspect of this invention allows fermentation of microorganisms without inhibiting the growth of the microorganism. Specifically, the bioreactor is designed to remove heat that accumulates inside the bioreactor during fermentation by conduction. Additionally, there is a mechanism to add fluid to the interior of the bioreactor that permits equal distribution and precise control of a variety of environmental parameters.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: December 16, 2003
    Assignee: Biocon India Limited
    Inventors: Shrikumar Suryanarayan, Kiran Mazumdar
  • Solid state fermentation
    Patent number: 6197573
    Abstract: The present invention provides an improved solid state fermentation device that combines all of the operations of microorganism cultivation (sterilization, inoculation, cultivation, extraction, and post extraction treatment). This solid state fermentation device is modular in nature and operates in a contained manner so that the live microorganisms from the reactor cannot come into contact with the environment and pollute the environment and also so that the environment inside the bioreactor is aseptic. Another aspect of this invention allows fermentation of microorganisms without inhibiting the growth of the microorganism. Specifically, the bioreactor is designed to remove heat that accumulates inside the bioreactor during fermentation by conduction. Additionally, there is a mechanism to add fluid to the interior of the bioreactor that permits equal distribution and precise control of a variety of environmental parameters.
    Type: Grant
    Filed: November 17, 1998
    Date of Patent: March 6, 2001
    Assignee: Biocon India Limited
    Inventors: Shrikumar Suryanarayan, Kiran Mazumdar