Patents by Inventor Shu-Chen Hsieh

Shu-Chen Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10787366
    Abstract: A method for manufacturing a graphitic sheet is used to obtain the graphitic sheet with similar characteristics to graphene. The method includes forming an octadecyltrichlorosilane (OTS) layer on a substrate to obtain a composite. The composite is annealed at 250-400° C. for 30-90 minutes, forming the graphitic sheet on the substrate via self-assembly of octadecyltrichlorosilane (OTS) in the OTS layer. The annealed composite is immersed in water, followed by being sonicated for 2 minutes with a frequency of 40 kHz and a power output of 200 W, to separate the graphitic sheet from the substrate.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: September 29, 2020
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventor: Shu-Chen Hsieh
  • Publication number: 20200063181
    Abstract: A fluorescent probe is obtained via hydrolysis and condensation reaction using 3-glycidoxypropyl trimethoxysilane. The fluorescent probe includes a silicon oxide core and a self-assembled monolayer. The self-assembled monolayer has an epoxide group, and joins the silicone oxide core by a covalent bond. The epoxide group of the fluorescent probe can form a conjugated bond with a molecule with an amino group via an aminolysis reaction, forming a nanoparticle including the molecule and the fluorescent probe.
    Type: Application
    Filed: October 28, 2019
    Publication date: February 27, 2020
    Inventors: SHU-CHEN HSIEH, PEI-YING LIN
  • Publication number: 20200039829
    Abstract: A method for manufacturing a graphitic sheet is used to obtain the graphitic sheet with similar characteristics to graphene. The method includes forming an ocatadecyltrichlorosilane (OTS) layer on a substrate to obtain a composite. The composite is annealed at 250-400° C. for 30-90 minutes, forming the graphitic sheet on the substrate via self-assembly of ocatadecyltrichlorosilane (OTS) in the OTS layer. The annealed composite is immersed in water, followed by being sonicated for 2 minutes with a frequency of 40 kHz and a power output of 200 W, to separate the graphitic sheet from the substrate.
    Type: Application
    Filed: September 4, 2018
    Publication date: February 6, 2020
    Inventor: Shu-Chen Hsieh
  • Publication number: 20180327808
    Abstract: A nanodot for detecting glucose concentration includes a silicon oxide core, a self-assembled monolayer having a 3-glycidoxypropyl trimethoxysilane group, and a glucose oxidase particle. The self-assembled monolayer joins the silicon oxide core by a covalent bond, and the glucose oxidase particle joins the 3-glycidoxypropyl trimethoxysilane group of the self-assembled monolayer by a conjugated bond. Moreover, a method for detecting glucose concentration by the nanodot includes oxidizing a glucose molecule in a glucose solution by the glucose oxidase particle of the nanodot, producing a hydrogen peroxide molecule; fluorescent quenching the nanodot by the hydrogen peroxide molecule, resulting in a change in fluorescent intensity of the nanodot; and detecting the change in fluorescent intensity of the nanodot.
    Type: Application
    Filed: June 14, 2017
    Publication date: November 15, 2018
    Inventors: SHU-CHEN HSIEH, PEI-YING LIN
  • Patent number: 9707522
    Abstract: The invention discloses a biocompatible semi-permeable membrane. The semi-permeable membrane is manufactured by: providing an eggshell membrane; and immersing the eggshell membrane in an aqueous hydrogen peroxide solution with a concentration of 0.35 to 35% for 8 to 144 hours.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: July 18, 2017
    Assignee: National Sun Yat-Sen University
    Inventor: Shu-Chen Hsieh
  • Patent number: 9303049
    Abstract: The present disclosure provides a method for manufacturing a nanodot, including: providing a hydrolysable silane, wherein the hydrolysable silane has one or more hydrolysable groups and one or more substituted or non-substituted hydrocarbon groups; and performing a one-step heat treatment to hydrolyze and condensate the hydrolysable silane to form a nanodot. The nanodot includes: a core, the core is selected from the group consisting of a semiconductor core or a metal core; and a self-assembled monolayer (SAM) including the substituted or non-substituted hydrocarbon groups, wherein the self-assembled monolayer is connected to the core by covalent bonds.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: April 5, 2016
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Shu-Chen Hsieh, Pei-Ying Lin
  • Publication number: 20150073167
    Abstract: The present disclosure provides a method for manufacturing a nanodot, including: providing a hydrolysable silane, wherein the hydrolysable silane has one or more hydrolysable groups and one or more substituted or non-substituted hydrocarbon groups; and performing a one-step heat treatment to hydrolyze and condensate the hydrolysable silane to form a nanodot. The nanodot includes: a core, the core is selected from the group consisting of a semiconductor core or a metal core; and a self-assembled monolayer (SAM) including the substituted or non-substituted hydrocarbon groups, wherein the self-assembled monolayer is connected to the core by covalent bonds.
    Type: Application
    Filed: June 2, 2014
    Publication date: March 12, 2015
    Applicant: National Sun Yat-sen University
    Inventors: Shu-Chen HSIEH, Pei-Ying LIN
  • Publication number: 20140374261
    Abstract: The invention discloses a biocompatible semi-permeable membrane. The semi-permeable membrane is manufactured by: providing an eggshell membrane; and immersing the eggshell membrane in an aqueous hydrogen peroxide solution with a concentration of 0.35 to 35% for 8 to 144 hours.
    Type: Application
    Filed: May 5, 2014
    Publication date: December 25, 2014
    Applicant: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventor: SHU-CHEN HSIEH
  • Patent number: 8808558
    Abstract: The invention provides a system and method for alignment of nanoparticles on a substrate. The system includes: a substrate; a plurality of polypeptide templates formed on the substrate; and a plurality of nanoparticles formed on the polypeptide templates. The method includes: providing a substrate; forming a plurality of polypeptide templates on the substrate; and forming a plurality of nanoparticles on the polypeptide templates.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: August 19, 2014
    Assignee: National Sun Yat-Sen University
    Inventor: Shu-Chen Hsieh
  • Patent number: 8728584
    Abstract: The invention provides a method for patterning a polymer surface. A polymer layer is formed on a substrate. A conductive grid with a mesh pattern is placed on the polymer layer. The mesh pattern is transferred to the polymer layer by a plasma treatment. The conductive grid is then removed.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: May 20, 2014
    Assignee: National Sun Yat-Sen University
    Inventor: Shu-Chen Hsieh
  • Patent number: 8575925
    Abstract: The invention provides a method for detecting and imaging magnetic metalloproteins. A substrate is provided. A plurality of magnetic metalloproteins are formed on the substrate. The magnetic metalloproteins are detected and imaged by magnetic force microscopy (MFM) to obtain topographic images, phase images and MFM images of the magnetic metalloproteins.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: November 5, 2013
    Assignee: National Sun Yat-Sen University
    Inventor: Shu-Chen Hsieh
  • Publication number: 20120128731
    Abstract: The invention provides a biocompatible carrier and method for fabricating the same. The biocompatible carrier includes: a gel, and a plurality of metal nanoparticles, an organic compound or combinations thereof embedded in the gel, wherein the metal nanoparticles, the organic compound or combinations thereof are uniformly distributed in the gel.
    Type: Application
    Filed: March 29, 2011
    Publication date: May 24, 2012
    Applicant: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventor: Shu-Chen Hsieh
  • Publication number: 20110227566
    Abstract: The invention provides a method for detecting and imaging magnetic metalloproteins. A substrate is provided. A plurality of magnetic metalloproteins are formed on the substrate. The magnetic metalloproteins are detected and imaged by magnetic force microscopy (MFM) to obtain topographic images, phase images and MFM images of the magnetic metalloproteins.
    Type: Application
    Filed: October 25, 2010
    Publication date: September 22, 2011
    Applicant: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventor: Shu-Chen Hsieh
  • Publication number: 20110186543
    Abstract: The invention provides a system and method for alignment of nanoparticles on a substrate. The system includes: a substrate; a plurality of polypeptide templates formed on the substrate; and a plurality of nanoparticles formed on the polypeptide templates. The method includes: providing a substrate; forming a plurality of polypeptide templates on the substrate; and forming a plurality of nanoparticles on the polypeptide templates.
    Type: Application
    Filed: January 31, 2011
    Publication date: August 4, 2011
    Inventor: Shu-Chen HSIEH
  • Publication number: 20100227079
    Abstract: The invention provides a method for patterning a polymer surface. A polymer layer is formed on a substrate. A conductive grid with a mesh pattern is placed on the polymer layer. The mesh pattern is transferred to the polymer layer by a plasma treatment. The conductive grid is then removed.
    Type: Application
    Filed: October 9, 2009
    Publication date: September 9, 2010
    Inventor: Shu-Chen Hsieh