Patents by Inventor Shu-Fang Chiang
Shu-Fang Chiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11629213Abstract: A graft polymer is provided, which includes a polymer backbone with a plurality of hydroxy groups, protection group modified histidine grafted onto the side of the polymer backbone, and hydrophilic polymer having terminal reactive group grafted onto the side of the polymer backbone. The graft polymer coating can be applied to metal material to form a composite material, which can be implanted into an organism to reduce adhesion problems.Type: GrantFiled: December 24, 2020Date of Patent: April 18, 2023Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ting-Yu Shih, Chia-Chun Wang, Lu-Chih Wang, Yuan-Kun Yu, Shu-Fang Chiang, Yi-Ting Hsieh, Yu-Chun Liu, Jing-Wen Tang
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Publication number: 20210198409Abstract: A graft polymer is provided, which includes a polymer backbone with a plurality of hydroxy groups, protection group modified histidine grafted onto the side of the polymer backbone, and hydrophilic polymer having terminal reactive group grafted onto the side of the polymer backbone. The graft polymer coating can be applied to metal material to form a composite material, which can be implanted into an organism to reduce adhesion problems.Type: ApplicationFiled: December 24, 2020Publication date: July 1, 2021Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ting-Yu SHIH, Chia-Chun WANG, Lu-Chih WANG, Yuan-Kun YU, Shu-Fang CHIANG, Yi-Ting HSIEH, Yu-Chun LIU, Jing-Wen TANG
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Publication number: 20160113905Abstract: A polymer composition including a polymer having a hydroxyl group and a histidine or a histidine derivative grafted to the polymer having a hydroxyl group. A polymer material is also provided, including a polymer composition which includes a polymer having a hydroxyl group, and a histidine or a histidine derivative grafted to the polymer having a hydroxyl group.Type: ApplicationFiled: December 22, 2015Publication date: April 28, 2016Inventors: Ting-Yu Shih, Tse-Min Teng, Chia-Chun Wang, Yu-Hua Chen, Jui-Hsiang Chen, Mei-Ju Yang, Shu-Fang Chiang, Yen-Chun Chen, Chia-Ni Chang
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Publication number: 20140186415Abstract: A polymer composition including a polymer having a hydroxyl group and a histidine or a histidine derivative grafted to the polymer having a hydroxyl group. A polymer material is also provided, including a polymer composition which includes a polymer having a hydroxyl group, and a histidine or a histidine derivative grafted to the polymer having a hydroxyl group.Type: ApplicationFiled: December 18, 2013Publication date: July 3, 2014Applicant: Industrial Technology Research InstituteInventors: Ting-Yu SHIH, Tse-Min TENG, Chia-Chun WANG, Yu-Hua CHEN, Jui-Hsiang CHEN, Mei-Ju YANG, Shu-Fang CHIANG, Yen-Chun CHEN, Chia-Ni CHANG
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Patent number: 7906333Abstract: A surface modification method of polysaccharide, the modified polysaccharide, and a method of culturing and recovery cells using the same are provided. The surface modification method of polysaccharide comprises (a) immersing a polysaccharide material in an acid, (b) immersing the polysaccharide material in an acidic solution containing a protein, and (c) immersing the polysaccharide material in an alkaline solution containing bivalent metal ions.Type: GrantFiled: March 21, 2006Date of Patent: March 15, 2011Assignee: Industrial Technology Research InstituteInventors: Chun-Jen Liao, Yung-chih Wu, Chen-Chi Tsai, Hsiang-Ming Huang, Yuan-Hua Hsu, Shu-Fang Chiang
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Patent number: 7767445Abstract: A porous chamber for tissue culture in vitro. The porous chamber includes a main body made of porous biologically absorbable polymer material, comprising an inner surface surrounding a hollow cavity, the hollow cavity having an aperture opened at an upper surface of the main body, wherein the aperture is communicated with outside of the main body for seeding tissue blocks in the hollow cavity, and an upper cover passing through the upper surface of the main body to seal the aperture to prevent the tissue blocks from outflowing.Type: GrantFiled: June 6, 2007Date of Patent: August 3, 2010Assignee: Industrial Technology Research InstituteInventors: Chun-Jen Liao, Yu-Ju Lin, Chin-Fu Chen, Ken-Yuan Chang, Shu-Fang Chiang
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Patent number: 7700355Abstract: A porous matrix, preparation thereof, and methods of using the same. The porous matrix of calcium alginate is prepared using a plurality of particles containing a multivalent cation, admixing the particles with ionic cross-linked polysaccharides and water to form a mixture, introducing a cross linker to solidify the mixture, dissolving the particles of the mixture in an acid to form a porous structure, and neutralizing and cross-linking the porous structure.Type: GrantFiled: January 7, 2005Date of Patent: April 20, 2010Assignee: Industrial Technology Research InstituteInventors: Chun-Jen Liao, Jui-Hsiang Chen, Chen-Chi Tsai, Yung-Chih Wu, Shu-Fang Chiang, Yi-Jung Hsiang
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Publication number: 20080026455Abstract: A porous chamber for tissue culture in vitro. The porous chamber includes a main body made of porous biologically absorbable polymer material, comprising an inner surface surrounding a hollow cavity, the hollow cavity having an aperture opened at an upper surface of the main body, wherein the aperture is communicated with outside of the main body for seeding tissue blocks in the hollow cavity, and an upper cover passing through the upper surface of the main body to seal the aperture to prevent the tissue blocks from outflowing.Type: ApplicationFiled: June 6, 2007Publication date: January 31, 2008Inventors: Chun-Jen Liao, Yu-Ju Lin, Chin-Fu Chen, Ken-Yuan Chang, Shu-Fang Chiang
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Publication number: 20070148768Abstract: A surface modification method of polysaccharide, the modified polysaccharide, and a method of culturing and recovery cells using the same are provided. The surface modification method of polysaccharide comprises (a) immersing a polysaccharide material in an acid, (b) immersing the polysaccharide material in an acidic solution containing a protein, and (c) immersing the polysaccharide material in an alkaline solution containing bivalent metal ions.Type: ApplicationFiled: March 21, 2006Publication date: June 28, 2007Inventors: Chun-Jen Liao, Yung-chih Wu, Chen-Chi Tsai, Hsiang-Ming Huang, Yuan-Hua Hsu, Shu-Fang Chiang
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Publication number: 20060153814Abstract: A porous matrix, preparation thereof, and methods of using the same. The porous matrix of calcium alginate is prepared using a plurality of particles containing a multivalent cation, admixing the particles with ionic cross-linked polysaccharides and water to form a mixture, introducing a cross linker to solidify the mixture, dissolving the particles of the mixture in an acid to form a porous structure, and neutralizing and cross-linking the porous structure.Type: ApplicationFiled: January 7, 2005Publication date: July 13, 2006Inventors: Chun-Jen Liao, Jui-Hsiang Chen, Chen-Chi Tsai, Yung-Chih Wu, Shu-Fang Chiang, Yi-Jung Hsiang
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Publication number: 20030109034Abstract: The method for tissue culture in vitro of the present invention is to partially digest the tissue blocks via enzyme, and then seed the partially digested tissue blocks into the hollow cavity of the porous chamber, wherein tissue grow three-dimensionally inside-out toward the surrounding pores of the porous chamber, thus new tissue is proliferated directly with the original tissue form, a method that cultures tissue needed in vitro by using the smallest quantity of tissue within the shortest period of time.Type: ApplicationFiled: August 9, 2002Publication date: June 12, 2003Applicant: Industrial Technology Research InstituteInventors: Chun - Jen Liao, Yu - Ju Lin, Chin - Fu Chen, Ken - Yuan Chang, Shu - Fang Chiang
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Patent number: 6436426Abstract: The present invention provides a process for producing porous polymer materials. In the present invention, a polymer material and a soluble material are mixed in their solid states. The surface of the polymer material is partially dissolved and fused by introducing a solvent. The present invention makes use of a pressure difference while introducing a non-solvent into the polymer material to solidify and resolve the solved polymer material. Then, a substantial amount of water is used to wash the inside soluble material out. Therefore, the porous polymer materials with high porosity and interconnecting pores inside the materials are produced massively and rapidly.Type: GrantFiled: May 30, 2001Date of Patent: August 20, 2002Assignee: Industrial Technology Research InstituteInventors: Chun-Jen Liao, Chin-Fu Chen, Jui-Hsiang Chen, Ken-Yuan Chang, Yure-Ru Lin, Shu-Fang Chiang
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Publication number: 20020022673Abstract: The present invention provides a process for producing porous polymer materials. In the present invention, a polymer material and a soluble material are mixed in their solid states. The surface of the polymer material is partially dissolved and fused by introducing a solvent. The present invention makes use of a pressure difference while introducing a non-solvent into the polymer material to solidify and resolve the solved polymer material. Then, a substantial amount of water is used to wash the inside soluble material out. Therefore, the porous polymer materials with high porosity and interconnecting pores inside the materials are produced massively and rapidly.Type: ApplicationFiled: May 30, 2001Publication date: February 21, 2002Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chun-Jen Liao, Chin-Fu Chen, Jui-Hsiang Chen, Ken-Yuan Chang, Yure-Ru Lin, Shu-Fang Chiang
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Patent number: 6323022Abstract: A cell-cultivating device includes a plurality of culture tanks and a driving device. The culture tanks communicate with each other and have culture medium inside. The driving device forces the culture medium to flow between the culture tanks so as to vertically oscillate medium levels in the culture tanks.Type: GrantFiled: July 1, 1999Date of Patent: November 27, 2001Assignee: Industrial Technology Research InstituteInventors: King-Ming Chang, Long-Shuenn Jean, Yu-Tai Liu, Chun-Chieh Chen, Ken-Yuan Chang, Shu-Fang Chiang