Patents by Inventor SHU-HSING YEH

SHU-HSING YEH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10865377
    Abstract: A method of preparing Cordyceps cicadae mycelium active substances for preventing and/or treating xerophthalmia is provided. The method comprises: (a) culturing a Cordyceps cicadae mycelium in a plate media at 15 to 35° C. for 5 to 14 days; (b) inoculating the mycelium of step (a) to a flask containing liquid media and culturing it at 15 to 35° C. with a pH of 2 to 8 for 3 days; (c) inoculating the mycelium of step (b) to a fermenter tank and culturing it at 15 to 35° C. with a pH of 2 to 8 for 3 days, so as to obtain a Cordyceps cicadae mycelium fermentation liquid; (d) freeze-drying and grating the fermentation liquid, so as to obtain a Cordyceps cicadae mycelium powder; (e) extracting the powder with solvent, so as to obtain a Cordyceps cicadae mycelium extract; and (f) drying the extract, so as to obtained the Cordyceps cicadae mycelium active substances.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: December 15, 2020
    Assignee: GRAPE KING BIO LTD.
    Inventors: Pei-Cheng Lin, Han-Hsin Chang, Chin-Chu Chen, Shu-Hsing Yeh, Li-Ya Lee, Jui-Hsia Hsu
  • Patent number: 10835563
    Abstract: The present invention provides a method for preventing, postponing or treating ocular diseases, including changes in the anterior/posterior chamber volume, vitreous humour, and/or retinal detachment. The method comprises administering to a subject an effective amount of Cordyceps cicadae mycelium active substances. A method for preparing Cordyceps cicadae mycelium active substances comprises following steps: (a) culturing a Cordyceps cicadae mycelium on a plate medium between 15-35° C. for 5-14 days; (b) inoculating the Cordyceps cicadae mycelium of step (a) into a flask and culturing the mycelium between 15-35° C. and pH 2-8 for 3-7 days; and (c) inoculating the Cordyceps cicadae mycelium of step (b) into a fermenter tank and culturing the mycelium by stirring between 15-35° C. and pH 2-8 for 3-5 days, so as to obtain a Cordyceps cicadae mycelium fermentation liquid containing the Cordyceps cicadae mycelium active substances.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: November 17, 2020
    Assignee: GRAPE KING BIO LTD.
    Inventors: Chin-Chu Chen, Shu-Hsing Yeh, Li-Ya Lee, Jui-Hsia Hsu
  • Publication number: 20200061134
    Abstract: The present invention provides a method for preventing, postponing or treating ocular diseases, including changes in the anterior/posterior chamber volume, vitreous humour, and/or retinal detachment. The method comprises administering to a subject an effective amount of Cordyceps cicadae mycelium active substances. A method for preparing Cordyceps cicadae mycelium active substances comprises following steps: (a) culturing a Cordyceps cicadae mycelium on a plate medium between 15-35° C. for 5-14 days; (b) inoculating the Cordyceps cicadae mycelium of step (a) into a flask and culturing the mycelium between 15-35° C. and pH 2-8 for 3-7 days; and (c) inoculating the Cordyceps cicadae mycelium of step (b) into a fermenter tank and culturing the mycelium by stirring between 15-35° C. and pH 2-8 for 3-5 days, so as to obtain a Cordyceps cicadae mycelium fermentation liquid containing the Cordyceps cicadae mycelium active substances.
    Type: Application
    Filed: December 20, 2018
    Publication date: February 27, 2020
    Applicant: GRAPE KING BIO LTD.
    Inventors: Chin-Chu CHEN, Shu-Hsing YEH, Li-Ya LEE, Jui-Hsia HSU
  • Patent number: 10342833
    Abstract: The present invention discloses the Cordyceps cicadae mycelia, the active substances of C. cicadae mycelia, its submerged fermentation product and its pharmaceutical composition for preventing, delaying or treating cataracts, and the methods for preparing the products above. The C. cicadae mycelia, the active substances of C. cicadae mycelia, its submerged fermentation product and its pharmaceutical composition further can be prepared as a health food for preventing or delaying cataracts.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: July 9, 2019
    Assignee: GRAPE KING BIO Ltd.
    Inventors: Pei-Cheng Lin, Han-Hsin Chang, Chin-Chu Chen, Yen-Lien Chen, Shu-Hsing Yeh, Li-Ya Lee, Jui-Hsia Hsu, Lee-Sar Sheng
  • Publication number: 20190008911
    Abstract: The present invention discloses the Cordyceps cicadae mycelia, the active substances of C. cicadae mycelia, its submerged fermentation product and its pharmaceutical composition for preventing, delaying or treating cataracts, and the methods for preparing the products above. The C. cicadae mycelia, the active substances of C. cicadae mycelia, its submerged fermentation product and its pharmaceutical composition further can be prepared as a health food for preventing or delaying cataracts.
    Type: Application
    Filed: November 30, 2017
    Publication date: January 10, 2019
    Applicant: GRAPE KING BIO Ltd.
    Inventors: Pei-Cheng Lin, Han-Hsin Chang, Chin-Chu Chen, Yen-Lien Chen, Shu-Hsing Yeh, Li-Ya Lee, Jui-Hsia Hsu, Lee-Sar Sheng
  • Publication number: 20180171282
    Abstract: A method of preparing Cordyceps cicadae mycelium active substances for preventing and/or treating xerophthalmia is provided. The method comprises: (a) culturing a Cordyceps cicadae mycelium in a plate media at 15 to 35° C. for 5 to 14 days; (b) inoculating the mycelium of step (a) to a flask containing liquid media and culturing it at 15 to 35° C. with a pH of 2 to 8 for 3 days; (c) inoculating the mycelium of step (b) to a fermenter tank and culturing it at 15 to 35° C. with a pH of 2 to 8 for 3 days, so as to obtain a Cordyceps cicadae mycelium fermentation liquid; (d) freeze-drying and grating the fermentation liquid, so as to obtain a Cordyceps cicadae mycelium powder; (e) extracting the powder with solvent, so as to obtain a Cordyceps cicadae mycelium extract; and (f) drying the extract, so as to obtained the Cordyceps cicadae mycelium active substances.
    Type: Application
    Filed: February 14, 2018
    Publication date: June 21, 2018
    Applicant: GRAPE KING BIO LTD.
    Inventors: Pei-Cheng LIN, Han-Hsin CHANG, Chin-Chu CHEN, Shu-Hsing YEH, Li-Ya LEE, Jui-Hsia HSU
  • Publication number: 20160312176
    Abstract: A method of preparing Cordyceps cicadae mycelium active substances for preventing and/or treating xerophthalmia is provided. The method comprises: (a)culturing a Cordyceps cicadae mycelium in a plate media at 15 to 35° C. for 5 to 14 days; (b)inoculating the mycelium of step(a) to a flask containing liquid media and culturing it at 15 to 35° C. with a pH of 2 to 8 for 3 days; (c)inoculating the mycelium of step(b) to a fermenter tank and culturing it at 15 to 35° C. with a pH of 2 to 8 for 3 days, so as to obtain a Cordyceps cicadae mycelium fermentation liquid; (d)freeze-drying and grating the fermentation liquid, so as to obtain a Cordyceps cicadae mycelium powder; (e)extracting the powder with solvent, so as to obtain a Cordyceps cicadae mycelium extract; and (f)drying the extract, so as to obtained the Cordyceps cicadae mycelium active substances.
    Type: Application
    Filed: November 12, 2015
    Publication date: October 27, 2016
    Applicant: GRAPE KING BIO LTD.
    Inventors: PEI-CHENG LIN, HAN-HSIN CHANG, CHIN-CHU CHEN, SHU-HSING YEH, LI-YA LEE, JUI-HSIA HSU