Abstract: A device is disclosed herein. The device includes a bias generator, an ESD driver, and a logic circuit. The bias generator includes a first transistor. The ESD driver includes a second transistor and a third transistor coupled to each other in series. The logic circuit is configured to generate a logic control signal. When the first transistor is turned on by a detection signal, the first transistor is turned off.

Abstract: A complementary current-steering digital-to-analog converter (DAC) including a p-type DAC as well as an n-type DAC is shown. The p-type DAC has p-type current sources, and the n-type DAC has n-type current sources. The p-type and n-type current sources are coupled to a first input terminal or a second input terminal of a transimpedance amplifier (TIA) according to the digital input of the complementary current-steering DAC. In response to the digital input changing from a first value to a second value that is greater than the first value, one or more n-type current sources connected to the second input terminal of the TIA are switched so that they are connected to the first input terminal of the TIA.

Abstract: A circuit with a pseudo class-AB structure is shown. The circuit has an output stage, a first capacitor, and a first impedance component. The output stage has a first PMOS (p-type Metal-Oxide-Semiconductor Field-Effect Transistor) and a first NMOS (n-type MOSFET). The first connection node between the drain terminal of the first PMOS and the drain terminal of the first NMOS is coupled to the first output terminal of the circuit. The first capacitor is coupled between the gate terminal of the first PMOS and the gate terminal of the first NMOS. The first impedance component is coupled in parallel with the first capacitor between the gate terminal of the first PMOS and the gate terminal of the first NMOS.

Abstract: Disclosed is a differential amplifier including an input circuit, a detecting and controlling circuit, and an output circuit. The input circuit outputs input current to two output nodes according to the voltage of a differential input signal and the voltage of a bias node. The detecting and controlling circuit outputs compensative current to the two output nodes according to control bias voltage and the voltage of the bias node, in which the voltage of the bias node and the compensative current relate to the voltage of the differential input signal. The output circuit is coupled to the two output nodes and outputs a differential output signal according to the sum of the input current and the compensative current. Due to the detecting and controlling circuit outputting the compensative current, the differential amplifier prevents itself from entering a deadlock state even though the input current is insufficient or zero.

Abstract: Disclosed is a differential amplifier including an input circuit, a detecting and controlling circuit, and an output circuit. The input circuit outputs input current to two output nodes according to the voltage of a differential input signal and the voltage of a bias node. The detecting and controlling circuit outputs compensative current to the two output nodes according to control bias voltage and the voltage of the bias node, in which the voltage of the bias node and the compensative current relate to the voltage of the differential input signal. The output circuit is coupled to the two output nodes and outputs a differential output signal according to the sum of the input current and the compensative current. Due to the detecting and controlling circuit outputting the compensative current, the differential amplifier prevents itself from entering a deadlock state even though the input current is insufficient or zero.

Abstract: A method of treating a Th1-mediated disorder includes administering to a subject in need of the treatment an effective amount of a compound of the formula I: wherein R1 is H, alkyl, aryl, or cyclyl; R2 is pyranose; R3 is H or alkyl; m is 2, 3, 4, 5, or 6; n is 0, 1, 2, or 3; o is 0, 1, 2, 3, 4; p is 1, 2, 3, or 4; and the Th1-mediated disorder is non-obese diabetes, Crohn's colitis, autoimmune hemolytic anemia, rheumatoid arthritis, autoimmune encephalitis, multiple sclerosis, or autoimmune myocarditis. Also disclosed is a pharmaceutical composition including a compound of formula I above and a pharmaceutically acceptable carrier.

Abstract: Methods useful, for example, in identifying plant compositions that have immunomodulatory activity. Also disclosed is an Asteraceae plant immunomodulatory composition useful for increasing an immune response, e.g., IFN ? or IL-2 transcription.

Abstract: A method of treating a Th1-mediated disorder includes administering to a subject in need of the treatment an effective amount of a compound of the formula I: wherein R1 is H, alkyl, aryl, or cyclyl; R2 is pyranose; R3 is H or alkyl; m is 2, 3, 4, 5, or 6; n is 0, 1, 2, or 3; o is 0, 1, 2, 3, 4; p is 1, 2, 3, or 4; and the Th1-mediated disorder is non-obese diabetes, Crohn's colitis, autoimmune hemolytic anemia, rheumatoid arthritis, autoimmune encephalitis, multiple sclerosis, or autoimmune myocarditis. Also disclosed is a pharmaceutical composition including a compound of formula I above and a pharmaceutically acceptable carrier.

Abstract: A method for treating a bacterial infection in a subject by administration of an effective amount of centaurein alone or in combination with a bacteriocide. Also described is a composition containing an effective combined amount of centaurein and a bacteriocide useful for treating a bacterial infection in a subject.

Abstract: A compound of the formula: wherein R1 is H, alkyl, aryl, or cyclyl; R2 is pyranose; R3 is H or alkyl; m is 2, 3, 4, 5, or 6; n is 0, 1, 2, or 3; o is 0, 1, 2, 3, 4; and p is 1, 2, 3, or 4. Also disclosed is use of the compound to inhibit Th1 differentiation, promote Th2 differentiation, and treat certain disorders.

Abstract: A method for treating a bacterial infection in a subject by administration of an effective amount of centaurein alone or in combination with a bacteriocide. Also described is a composition containing an effective combined amount of centaurein and a bacteriocide useful for treating a bacterial infection in a subject.

Abstract: Methods useful, for example, in identifying plant compositions that have immunomodulatory activity. Also disclosed is an Asteraceae plant immunomodulatory composition useful for increasing an immune response, e.g., IFN ? or IL-2 transcription.