Abstract: A detachable atomizing device and a container thereof are provided. The container is detachably assembled to an atomizing assembly. The container includes a cup and a flexible film. The cup has an opening arranged at an end thereof, the flexible film covers the opening of the cup, and the flexible film has a tension region and an outer ring-shaped region that surrounds the tension region. The tension region has a plurality of atomizing holes having an average diameter within a range of 1 ?m to 20 ?m, and the outer ring-shaped region is attached to the cup. When the cup is assembled to the atomizing assembly, a tension value of the tension region of the flexible film is increased from an initial tension value to an atomizing tension value by being pressed from the atomizing assembly, and the atomizing holes of the tension region are configured to allow liquid to pass there-through and to be formed as aerosol mist having an average atomized particle diameter less than a predetermined value.

Abstract: An assembly method of an apparatus suitable for pressurized liquid transfusion is disclosed. In one step, a nozzle is to be inserted into the through hole of an elastomeric ring. Because the dimension of the nozzle is larger than the through hole, the internal wall of the elastomeric ring is tensioned and deformed so as to fit the nozzle. In one step, the elastomeric ring along with the nozzle is inserted into a receptacle. The dimension of the outer contour of the elastomeric ring needs to be decreased so as to be accommodated by the receptacle. Due to the flexibility of the elastomeric ring, it resumes at least partially to its original shape. Therefore, proper seal is created and maintained between the elastomeric ring and the nozzle such that leakage and pressure loss may be prevented. The foregoing is capable of working under high-pressured environment for prolonged use.

Abstract: An apparatus suitable for pressurized liquid transfusion is disclosed. The apparatus includes a nozzle assembly enclosed by the combination of a casing and a check nut. The nozzle assembly includes an elastomeric ring and a nozzle received by the combination of a cap and a receptacle. The elastomeric ring surrounds the nozzle and a proper seal is created therebetween. The dimension of the internal contour of the elastomeric ring is a bit smaller than the nozzle. The elastomeric ring is stretched so as to receive the nozzle. Additional processing may be applied to the elastomeric ring to achieve a different type of proper seal. Pressurized liquid passes through the apparatus so as to be transfused. The aforementioned seal serves to avoid leakage or pressure loss at the apparatus so as to avoid undesired aerosolization effects of an aerosolizer the apparatus is installed in.

Abstract: A microneedle structure and a biodegradable microneedle thereof are provided. The biodegradable microneedle defining a central axis includes a first step portion and a second step portion that is taperedly extending from the first step portion along the central axis. The biodegradable microneedle has a total height along the central axis and a maximum internal diameter along a direction perpendicular to the central axis. The total height is within a range of 380-430 ?m, and an aspect ratio defined by the total height divided by the maximum internal diameter is within a range of 1.2-2.2. In a cross section of the biodegradable microneedle having the central axis, a part of the second step portion arranged away from the first step portion having a corner. The corner has an angle within a range of 65-100 degrees and faces toward the first step portion.

Abstract: An atomization device includes a liquid storing member that stores a liquid therein, a carrier detachably assembled to the liquid storing member, an opener disposed on at least one of the liquid storing member and the carrier, and an atomizing module that is assembled to at least one of the liquid storing member and the carrier. The opener is configured to form an opening on the liquid storing member. The atomization device has a buffering chamber arranged between the atomizing module and the opening of the liquid storing member, and a volume of the buffering chamber is less than a volume of the liquid. The liquid storing member can be pressed to change an inner pressure thereof, such that a part of the liquid is driven to flow from the opening into the buffering chamber for an atomizing process of the atomizing module.

Abstract: An aerosol generating apparatus is disclosed. The apparatus includes a liquid container, an adaptor detachably engaged with the liquid container, and a driving element accommodated by the adaptor. A perforated membrane, through which a liquid can pass through, is disposed at an exit of the liquid container. Moreover, the perforated membrane faces the driving element. The driving element includes a substrate coupled with a piezoelectric element. The substrate includes an aperture that corresponds to the perforated membrane when the liquid container and the adaptor are engaged so as to receive liquid. Moreover, when the liquid container and the adaptor are engaged, the perforated membrane is in contact with the substrate at the proximity of the aperture, which is about the substrate's center. The adaptor is configured to contact the substrate's periphery only. The resulting apparatus generates aerosol at a desired efficiency with less energy needed.

Abstract: An aerosol generating apparatus is disclosed. The apparatus includes a liquid container, an adaptor and a driving element. The liquid container includes a perforated membrane through which a liquid can permeate. The liquid container further includes a first mating element. The adaptor includes a second mating element. The driving element includes a piezoelectric element coupled to a substrate. The driving element is accommodated by the adaptor and the substrate includes an aperture and a projection. The first and second mating elements are adapted to detachably and slidably mate with each other such that the aperture of the substrate aligns proximately to the center of the perforated membrane. The first and second mating elements are further adapted for relative movement along a sliding axis. The projection is adapted to press against the perforated membrane.

Abstract: A method and a circuit system for driving a nebulizer are provided. When the nebulizer receives acoustic waves, a control circuit extracts audio signals from the acoustic waves. Afterwards, the control circuit determines if the audio signals are within a predetermined frequency range, and can determine whether or not to drive a circuit to produce an aerosol based on the audio signals. Further, a volume of the acoustic waves can also be used to determine whether or not to produce the aerosol, and also determine an output rate of the aerosol. The circuit system of the nebulizer includes an audio receiver for receiving the acoustic waves, an aerosol generator for producing the aerosol, and the control circuit used to control a driving circuit of the aerosol generator to drive a vibrational element to produce the aerosol through vibration in response to the audio signals and the volume.

Abstract: A detachable atomizing device and a container thereof are provided. The container is detachably assembled to an atomizing assembly. The container includes a cup and a flexible film. The cup has an opening arranged at an end thereof, the flexible film covers the opening of the cup, and the flexible film has a tension region and an outer ring-shaped region that surrounds the tension region. The tension region has a plurality of atomizing holes having an average diameter within a range of 1 ?m to 20 ?m, and the outer ring-shaped region is attached to the cup. When the cup is assembled to the atomizing assembly, a tension value of the tension region of the flexible film is increased from an initial tension value to an atomizing tension value by being pressed from the atomizing assembly, and the atomizing holes of the tension region are configured to allow liquid to pass there-through and to be formed as aerosol mist having an average atomized particle diameter less than a predetermined value.

Abstract: A microneedle structure and a biodegradable microneedle thereof are provided. The biodegradable microneedle defining a central axis includes a first step portion and a second step portion that is taperedly extending from the first step portion along the central axis. The biodegradable microneedle has a total height along the central axis and a maximum internal diameter along a direction perpendicular to the central axis. The total height is within a range of 380-430 ?m, and an aspect ratio defined by the total height divided by the maximum internal diameter is within a range of 1.2-2.2. In a cross section of the biodegradable microneedle having the central axis, a part of the second step portion arranged away from the first step portion having a corner. The corner has an angle within a range of 65-100 degrees and faces toward the first step portion.

Abstract: An assembly method of an apparatus suitable for pressurized liquid transfusion is disclosed. In one step, a nozzle is to be inserted into the through hole of an elastomeric ring. Because the dimension of the nozzle is larger than the through hole, the internal wall of the elastomeric ring is tensioned and deformed so as to fit the nozzle. In one step, the elastomeric ring along with the nozzle is inserted into a receptacle. The dimension of the outer contour of the elastomeric ring needs to be decreased so as to be accommodated by the receptacle. Due to the flexibility of the elastomeric ring, it resumes at least partially to its original shape. Therefore, proper seal is created and maintained between the elastomeric ring and the nozzle such that leakage and pressure loss may be prevented. The foregoing is capable of working under high-pressured environment for prolonged use.

Abstract: An apparatus suitable for pressurized liquid transfusion is disclosed. The apparatus includes a nozzle assembly enclosed by the combination of a casing and a check nut. The nozzle assembly includes an elastomeric ring and a nozzle received by the combination of a cap and a receptacle. The elastomeric ring surrounds the nozzle and a proper seal is created therebetween. The dimension of the internal contour of the elastomeric ring is a bit smaller than the nozzle. The elastomeric ring is stretched so as to receive the nozzle. Additional processing may be applied to the elastomeric ring to achieve a different type of proper seal. Pressurized liquid passes through the apparatus so as to be transfused. The aforementioned seal serves to avoid leakage or pressure loss at the apparatus so as to avoid undesired aerosolization effects of an aerosolizer the apparatus is installed in.

Abstract: A microstructured passage module for aerosolizer is disclosed. The module includes a plate overlaid by a cover, an entrance, an exit, a plurality of protrusions and a plurality of pillars. The protrusions and pillars project from and are integral parts of the plate. Further, the plate can be divided into a first zone proximate to the entrance and a second zone proximate to the exit. The protrusions are arranged into parallel rows in a direction from the entrance to the exit and form parallel passages therebetween in the first zone for the liquid to flow along. The protrusions in each column are spaced from one another by tunnels. The pillars are interposingly disposed in the second zone and define certain channels therebetween. Moreover, a plurality of pillars further disposed in the passages increase a flow resistance for the liquid flowing through the passages.

Abstract: An aerosol generating apparatus is disclosed. The apparatus includes a liquid container, an adaptor and a driving element. The liquid container includes a perforated membrane through which a liquid can permeate. The liquid container further includes a first mating element. The adaptor includes a second mating element. The driving element includes a piezoelectric element coupled to a substrate. The driving element is accommodated by the adaptor and the substrate includes an aperture and a projection. The first and second mating elements are adapted to detachably and slidably mate with each other such that the aperture of the substrate aligns proximately to the center of the perforated membrane. The first and second mating elements are further adapted for relative movement along a sliding axis. The projection is adapted to press against the perforated membrane.

Abstract: An aerosol generating apparatus is disclosed. The apparatus includes a liquid container, an adaptor detachably engaged with the liquid container, and a driving element accommodated by the adaptor. A perforated membrane, through which a liquid can pass through, is disposed at an exit of the liquid container. Moreover, the perforated membrane faces the driving element. The driving element includes a substrate coupled with a piezoelectric element. The substrate includes an aperture that corresponds to the perforated membrane when the liquid container and the adaptor are engaged so as to receive liquid. Moreover, when the liquid container and the adaptor are engaged, the perforated membrane is in contact with the substrate at the proximity of the aperture, which is about the substrate's center. The adaptor is configured to contact the substrate's periphery only. The resulting apparatus generates aerosol at a desired efficiency with less energy needed.

Abstract: A nebulization structure includes a driving element, a structure plate and a nebulization plate. The structure plate is installed on a side of the driving element, and the structure plate is substantially in a circular disc shape and has a plurality of through holes, and at least one rib is formed between adjacent through holes to define a water guide passage. The nebulization plate is clamped between the driving element and the structure plate and made of a polymer material to overcome the problems of having easy metal fatigue and embrittlement of the nebulization plate made of metal, and being corroded by corrosive liquids.

Abstract: A nebulizer with a negative pressure structure includes a nebulization body, a carrying cavity, a nebulizing element and a negative pressure generating element. The carrying cavity is provided for carrying a nebulized liquid and has a through hole. The nebulizing element is installed at the through hole and includes a piezoelectric driving unit and a nebulizing plate disposed on a side of the piezoelectric driving unit. The negative pressure generating element is formed on the carrying cavity and provided for changing the volume of the carrying cavity or removing air from the carrying cavity to reduce the air pressure in the carrying cavity, so as to nebulize a liquid of low surface tension or high viscosity effectively.

Abstract: Disclosed is a dual air-chamber fully sealed piezoelectric nebulization module including a first casing, a second casing and a piezoelectric nebulization module, and the piezoelectric nebulization module is clamped between the casings by snapping and sealing to partition the internal space in the first casing and the second casing into two independent air chambers. In this design, a peripheral portion of the piezoelectric nebulization module is packaged to reduce the energy and vibration from being absorbed or inhibited during vibration and provides a space with good support and free vibration to enhance the nebulization efficiency. In addition, the design with the two independent air chambers can achieve the double-barrier sealing and isolating effect and reduce the chance of the piezoelectric nebulization module being corroded or damaged.

Abstract: A nebulization structure with a nozzle plate includes a nozzle plate and a driving element. The nozzle plate is composed of a polymer and a support plate, and the support plate includes a plurality of connecting portions and a through hole, and the polymer covers the support plate and has a plurality of penetrating holes corresponding to the through hole. The driving element is coupled to the nozzle plate through the connecting portions for producing a high-frequency vibration wave through a piezoelectric effect after power is supplied and driving the nozzle plate to vibrate and break up the molecular structure of a solution into a mist, so as to achieve the nebulization effect. The nebulization structure can be installed in a nebulization apparatus to achieve a high-efficiency nebulization effect by the nozzle plate and the driving element, so as to facilitate the manufacturing process and save costs.

Abstract: Disclosed is a dual air-chamber fully sealed piezoelectric nebulization module including a first casing, a second casing and a piezoelectric nebulization module, and the piezoelectric nebulization module is clamped between the casings by snapping and sealing to partition the internal space in the first casing and the second casing into two independent air chambers. In this design, a peripheral portion of the piezoelectric nebulization module is packaged to reduce the energy and vibration from being absorbed or inhibited during vibration and provides a space with good support and free vibration to enhance the nebulization efficiency. In addition, the design with the two independent air chambers can achieve the double-barrier sealing and isolating effect and reduce the chance of the piezoelectric nebulization module being corroded or damaged.