Patents by Inventor Shua-ku Huang

Shua-ku Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene expression vaccine
    Patent number: 7118888
    Abstract: An effective prophylactic mucosal gene expression vaccine (GXV), made up of a cocktail of at least 4 different plasmid DNAs encoding corresponding RSV antigens, coacervated with chitosan to formulate nanospheres. In a murine model of RSV infection, intranasal administration with GXV results in significant induction of RSV-specific antibodies, nasal IgA antibodies, cytotoxic T lymphocytes, and IFN-? production in the lung and splenocytes. A single dose of GXV induces a drastic reduction of viral titers.
    Type: Grant
    Filed: February 12, 2002
    Date of Patent: October 10, 2006
    Assignees: University of South Florida Board of Trustees, Johns Hopkins University
    Inventors: Shyam S. Mohapatra, Mukesh Kumar, Shua-ku Huang, Kam Leong
  • Gene expression vaccine
    Publication number: 20030068333
    Abstract: An effective prophylactic mucosal gene expression vaccine (GXV), made up of a cocktail of at least 4 different plasmid DNAs encoding corresponding RSV antigens, coacervated with chitosan to formulate nanospheres. In a murine model of RSV infection, intranasal administration with GXV results in significant induction of RSV-specific antibodies, nasal IgA antibodies, cytotoxic T lymphocytes, and IFN-&ggr; production in the lung and splenocytes. A single dose of GXV induces a drastic reduction of viral titers.
    Type: Application
    Filed: February 12, 2002
    Publication date: April 10, 2003
    Inventors: Shyam S. Mohapatra, Mukesh Kumar, Shua-ku Huang, Kam Leong