Abstract: Disclosed are a polyethylene glycol conjugate drug, and a preparation method therefor and the use thereof. Specifically, the present invention relates to a polyethylene glycol conjugate drug represented by formula A or a pharmaceutically acceptable salt thereof, a method for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, an intermediate for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, and the use of the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof in the preparation of a drug.

Abstract: An underwater and aerial vehicle includes a fixing frame, a core navigation system and an energy supply system. The fixing frame has a circular ring configuration in a middle part thereof, and the waterproof sealing cabin is fixed in the circular ring configuration, and multiple cantilever arms extend around the circular ring configuration. An underwater navigation control module and a relay are provided on an auxiliary fixing platform. A second brushless motor is provided on each of the cantilever arms. Each second brushless motor is provided with a marine propeller. A flight control module, a remote control receiver and a power management module are provided on a fixing platform. A first brushless motor is provided on each of the cantilever arms. Each first brushless motor is provided with a rotor via a coupling. The energy supply system is arranged in a lower part of the waterproof sealing cabin.

Abstract: Navigation video generation and acquisition methods and apparatuses, a server, a device, and a medium are provided, which relate to the field of navigation technologies. The method includes: receiving, from a terminal, a navigation video obtaining request, the navigation video obtaining request including a route origin and a route destination within an indoor scene; determining, based on the route origin and the route destination, one or more second sub-videos from one or more first sub-videos corresponding to a point of interest (POI) route relationship graph, the POI route relationship graph including a navigation route between at least two POIs in the indoor scene; determining an identifier to a navigation video from the route origin to the route destination based on the one or more second sub-videos; and returning the identifier to the navigation video to the requesting terminal for displaying the navigation video at the terminal.

Abstract: In some embodiments, a method analyzes content of a video to generate a representation for a video that represents a relationship of a bitrate to a quality measurement for the video. A plurality of candidate points on the representation are selected. Then, the method selects a profile ladder from at least a portion of the plurality of candidate points. Each profile in the profile ladder is associated with a candidate point and the profile includes a corresponding bitrate and a quality measurement for the respective candidate point. The profile ladder is used for the video.

Abstract: In some embodiments, a method generates a representation for a video that represents a relationship of a bitrate to a quality measurement for the video and selects candidate transcoding points on the representation. A plurality of candidate profile ladders are generated based on the candidate transcoding points. Each of the plurality of candidate profile ladders includes a different combination of profiles and a profile is associated with at least one of a bitrate and a quality measurement. The method selects a profile ladder from the plurality of candidate profile ladders based on analyzing the bitrate or the quality of the profile ladder and uses the profile ladder for the video.

Abstract: Embodiments of the present invention provide a video processing method, including: parsing, by a buffer server, a video file, and creating a video index file, where the index file includes a position of a key frame in the video file; receiving information about a target position of video dragging and sent by a client; determining a key frame closest to the target position according to the index file and the target position; and sending video file data that begins with a position of the closest key frame to the client so that the client starts playing from the target position. Correspondingly, the embodiments of the present invention further provide a buffer server, which solves the problem that a video without a file header and a video dragged beyond a storage range of a server cannot be played after being dragged, and improves user experience.

Abstract: The present invention provides a real-time transcoding method and device. The transcoding device obtains the current first transcoding speed, and adjusts the transcoding parameter according to the first transcoding speed and the preset second transcoding speed so as to perform real-time conversion for the media stream by using the adjusted transcoding parameter, which solves the problem that the real-time transcoding flexibility is reduced because the transcoding device uses a fixed transcoding parameter to perform real-time conversion for the media stream in the prior art.

Abstract: Embodiments of the present invention provide a video processing method, including: parsing, by a buffer server, a video file, and creating a video index file, where the index file includes a position of a key frame in the video file; receiving information about a target position of video dragging and sent by a client; determining a key frame closest to the target position according to the index file and the target position; and sending video file data that begins with a position of the closest key frame to the client so that the client starts playing from the target position. Correspondingly, the embodiments of the present invention further provide a buffer server, which solves the problem that a video without a file header and a video dragged beyond a storage range of a server cannot be played after being dragged, and improves user experience.