Abstract: The present disclosure is directed to the use of inhibitors of glutamate metabolism to treat cancers that have mutations in ARID1A. Thus, in accordance with the present disclosure, there is provided a method of treating a subject determined to have an ARIDIA-mutated cancer, pre-cancer or benign tumor comprising administering to said subject at least one inhibitor of glutamate metabolism.

Abstract: A power quality compensation system has the functions of controlling the bus voltage and the current peak value. A first instruction current under control of a first peak current processing unit is lower than or equal to a first current threshold value. A second peak current processing unit outputs a second PWM driving signal according to a sampled current and a second current threshold value. A third peak current processing unit outputs a third PWM driving signal according to the sampled current and a third current threshold value. A conversion unit is operated according to the PWM driving signals. Moreover, the first current threshold value is adjusted in real time according to the comparing result of the sample current and the first current threshold value and the comparing result of the real DC bus voltage and the reference DC bus voltage.

Abstract: A power quality compensation system has the functions of controlling the bus voltage and the current peak value. A first instruction current under control of a first peak current processing unit is lower than or equal to a first current threshold value. A second peak current processing unit outputs a second PWM driving signal according to a sampled current and a second current threshold value. A third peak current processing unit outputs a third PWM driving signal according to the sampled current and a third current threshold value. A conversion unit is operated according to the PWM driving signals. Moreover, the first current threshold value is adjusted in real time according to the comparing result of the sample current and the first current threshold value and the comparing result of the real DC bus voltage and the reference DC bus voltage.

Abstract: Described herein are unit cells including a base plate; a top plate; and a lumen extending longitudinally from the base plate to the top plate, the lumen defined by a side wall formed from a plurality of cojoined panels extending between a bottom surface of the top plate and a top surface of the base plate. The unit cell can be magnetically actuatable, such that the unit cell can be reversibly transitioned between a contracted configuration, an extended configuration, or a combination thereof using an applied magnetic field.

Abstract: A power quality compensator device and a control method thereof are provided. The power quality compensator device is electrically connected to a power grid and a nonlinear load, and includes a current controller, a converter, a ripple predictor, a processing unit and a voltage controller. The current controller is configured to receive an instruction current and output a switch control signal. The converter is configured to output an output current and an actual DC bus voltage according to the switch control signal. The ripple predictor is configured to receive an intermediate voltage and a first current and output a predicted ripple voltage. The processing unit is configured to output a processing result according to the actual DC bus voltage, the predicted ripple voltage and a reference DC bus voltage. The voltage controller is configured to receive the processing result and output a voltage control signal to the current controller.

Abstract: Disclosed a method for preparing a matrix protective coating, including a preprocessing step and a like transfer membrane coating preparation step. The like transfer membrane coating preparation step includes the following steps: mixing, drying and cooling YSZ powder and polytetrafluoroethylene powder to obtain a mixture, and then spraying the mixture onto the surface of a preprocessed matrix by an atmospheric plasma spraying method, wherein spraying parameters are set as follows: a moving speed of a spray gun is 440-460 mm/s; the current is 550-600 A, the voltage is 40-50 V, and the power is 24.8-30 kW; the compressed air is 0.6-0.7 MPa; the powder feeding carrier gas Ar is 3-6 L/min; a powder feeding rate is 25-28 g/min; and a spraying distance is 108-112 mm. The wear resistance of the coating of the present invention is significantly improved; the corrosion resistance is excellent; and the superhydrophobic property is excellent.

Abstract: A fast blind plate switching device, comprising a sealing structure, a clamping structure, a support structure and an execution mechanism. The blind plate has an open-state structure and a blind-state structure. The support structure is used for connecting pipelines at two sides and providing support for the whole device. The clamping structure and the sealing structure are located inside the support structure. The clamping structure is driven by the execution mechanism, and under the drive of the execution mechanism, the clamping structure presses on the blind plate (1) to eliminate a gap between two sides of the blind plate, so that a seal is formed by means of the sealing structure. When a gap is formed away from the blind plate (1), the open/blind state of the blind plate (1) is switched.

Abstract: The present invent belongs to the technical field of plating by sputtering coating forming materials, and particularly relates to a contact coating of an electrical connector. In the coating, chromium nitride is doped with precious metal elements.

Abstract: A wear-resistant super-hydrophobic protective coating for a substrate includes a pretreated surface and a composite coating. The composite coating is formed of a mixture of a ZrO2 powder, a PTFE powder and a silicone powder by spraying. A method for preparing the protective coating on a substrate is also provided.

Abstract: A fast blind plate switching device is provided, including a sealing structure, a clamping structure, a support structure and an execution mechanism. The blind plate has an open-state and a blind-state. The support structure is used for connecting pipelines at two sides and providing support for the whole device. The clamping structure and the sealing structure are located inside the support structure. The clamping structure is driven by the execution mechanism, and under the drive of the execution mechanism, the clamping structure presses on the blind plate to eliminate a gap between two sides of the blind plate, so that sealing is formed by means of the sealing structure. When a gap is formed away from the blind plate, the open/state and the blind state of the blind plate is switched.

Abstract: A direct method for manufacturing a large model fractured core and maintaining original oil-water saturation, including the following steps: (1) determining the volume V, porosity ?, permeability K, oil saturation So, water saturation Sw and the like of a fractured core to be manufactured; (2) preparing simulated oil, and determining the used oil mass mo=Vo×?o; (3) under the circumstance of no consideration of oil saturation, acquiring the mass of the used water, cement and quartz sand; (4) while establishing oil saturation, acquiring the mass mw of water for manufacturing the core as mw=a?Vo×?w; (5) mixing oil, water and an emulsifier evenly to prepare an oil-in-water emulsion; (6) adding cement and quartz sand into the emulsion and stirring evenly to obtain cement slurry; (7) when a cement sample is in a semi-solidified state, cutting the cement sample with a steel wire; and (8) solidifying the cement sample to the end.

Abstract: The present invention relates to a Beclin 1-UVRAG complex structure which reveals a tightly packed coiled coil assembly with Beclin 1 and UVRAG residues complementing each other to form a stable dimeric complex. This potent physical interaction is critical for UVRAG-dependent EGFR degradation but less critical for autophagy. Targeting the Beclin 1 coiled coil domain with rationally designed stapled peptides leads to enhanced autophagy activity and EGFR degradation in non-small cell lung cancer (NSCLC) cell lines, suggesting translational value for these compounds.

Abstract: A method assesses the rotational speed of a machine, and more particularly the rotational speed of a rotating equipment prime mover controlled by a governor. Such machines include turbo machinery and relate to a measurement device for measuring speed. The method measures a number of pulses during a measurement interval, determines a portion of a pulse pattern, determines an integration period, and calculates the rotational speed based on the portion of the pulse pattern.

Abstract: The invention discloses a functional electrical stimulation device including a headset, an electrical stimulation patch, an LED display screen, a circuit board, a rechargeable battery and a wireless terminal, and a method for using same. Two headphone bodies are symmetrically disposed on the headset, the circuit board and rechargeable battery are respectively mounted on the headphone bodies, and a music control button and an electrical stimulation mode and time control button are mounted on the two headphone bodies respectively. Two electrical stimulation patches are mounted on a middle portion of the headset, two LED display screens are respectively mounted on the two electrical stimulation patches. An audio decoder chip, a button control module, a power switch, an electrical stimulation generation module, a wireless communications module and a charging port are disposed on the circuit board, and the wireless terminal is independently disposed and in wireless communication with the circuit board.

Abstract: A system may receive a content identifier corresponding to content to be accessed via a toll free data service (toll-free data service). The system may determine, based on the content identifier, whether a content provider device, associated with the content, is configured with a serving component associated with serving the content via the toll-free data service. The system may provide an indication of whether the content provider device is configured with the serving component. The content may be accessible via the toll-free data service when the content provider device is configured with the serving component.

Abstract: A manufacturing method of a big-model low-permeability microcrack core includes: (1) determining the size of a microcrack core to be manufactured; (2) placing stones in a baking oven to bake for 24h under 120° C., placing the stones into a mixer, mixing and spraying oil, enabling the oil to seep into the stone, evenly forming a thin oil film on stone's surface; (3) mixing the oil sprayed stone with quartz sand and cement, adding water to mix evenly to obtain cement paste; (4) spreading butter on core mold's inner surface to form a thin butter film, pouring the cement paste into the core mold to obtain a cement sample; (5) loading confining pressure outside the core according to the requirements of porosity and permeability of the mold to adjust a pore permeability value; (6) obtaining the big-model core with microcrack after the cement sample is dried and formed.

Abstract: The present invention discloses a light-operated adjustable terahertz wave attenuator. The attenuator includes a silicon base-silicon base-vanadium oxide thin film, a laser emitter and a spherical collimating lens, wherein the silicon based-vanadium dioxide thin film is vertical to a terahertz beam direction, the laser emitter is arranged on one side of the silicon based-vanadium dioxide thin film, the laser emitter is connected with the collimator, the laser emitted from the laser emitter is emitted from the collimator and irradiates on a film surface of the silicon based-vanadium oxide thin film, and the spots of the laser irradiating on the film surface of the silicon based-vanadium oxide thin film completely cover the transmitted terahertz wave spots. The present invention further discloses a use method of the light-operated adjustable terahertz wave attenuator.

Abstract: A semiconductor device with die tilt control is disclosed. In one embodiment, a semiconductor device is provided comprising: a substrate; a first semiconductor die stacked on the substrate; and a plurality of additional semiconductor dies stacked on the first semiconductor die, wherein the plurality of additional semiconductor dies are stacked in an offset configuration, such that an edge of each of the plurality of additional semiconductor dies overhangs an edge of the semiconductor die on which it is stacked; wherein a thickness of a top-most semiconductor die of the plurality of additional semiconductor dies is greater than a thickness of any of the other additional semiconductor dies. Other embodiments are provided.

Abstract: A smart load-sensing EHA, comprising a variable displacement hydraulic pump, a symmetrical hydraulic cylinder, a feedback module, a pressure-following valve and an execution mechanism. The symmetrical hydraulic cylinder includes a symmetrical plunger, a first cylinder and a second cylinder separated by the plunger. The variable displacement hydraulic pump includes an oil inlet and an oil outlet. An output of the feedback module is to output a greater one of pressures at the first input and the second input to the execution mechanism. The pressure-following valve is connected between the output of the feedback module and an input end of the execution mechanism to reduce an instantaneous flow input to the input end of the execution mechanism and adjust pressure at the input end thereof. The execution mechanism is to receive an output of the feedback module and generate signal for changing displacement of the variable displacement hydraulic pump.

Abstract: A first device may obtain a session time record that includes information relating to a secure session. The session time record may include a content identifier and a device identifier that is associated with a second device. The content identifier may be associated with content to be provided via a secure session and via the second device. The content may be associated with a sponsored data campaign. The first device may obtain, from the second device, data usage information identifying an amount of data provided via the second device and in association with the secure session. The first device may determine information identifying a party responsible for the amount of data provided in association with the secure session based on the session time record and based on the data usage information. The first device may store or provide the information identifying the party responsible for the amount of data.